Análise morfométrica das fibras colágenas e reticulínicas na extrofia vesical / Morphometric analysis of collagen and reticulin fibers in classical bladder exstrophy

AUTOR(ES)
DATA DE PUBLICAÇÃO

2004

RESUMO

A prospective study was done to evaluate the detrusor muscles extracellular matrix in classical bladder exstrophy in comparison to a control group, by use of light microscopy and polarization method with morphometry, to quantify collagen and reticular fibers. Seventeen patients from both sexes were analysed and samples were obtained from the bladder and stained with Haematoxylin-eosin, Picrosirius red and the silver impregnation method. There were significant differences when comparing the quantity of collagen and reticular fibers. The collagen fibers were more abundant in the exstrophy bladders compared to controls, while the reticular fibers were present in smaller amounts.

ASSUNTO(S)

collagen/analysis prospective studies colágeno/análise reticulina/análise staining/methods coloração/métodos bladder diseases/pathology doenças da bexiga/patologia reticulin/analysis data interpretation statistical interpretação estatística de dados case-control studies estudos de casos e controles doenças da bexiga/cirurgia bladder diseases/surgery estudos prospectivos

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