An easy synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and arylamidoximes mediated by ethyl chloroformate

AUTOR(ES)

Neves Filho, Ricardo A. W., Bezerra, Natércia M. M., Guedes, José M., Srivastava, Rajendra M.

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2009

RESUMO

Uma síntese limpa, fácil e eficiente de vários 1,2,4-oxadiazóis 3,5-dissubstituídos partindo de um anidrido misto (gerado a partir de um ácido carboxílico e cloroformiato de etila) e amidoxima é descrita.

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