A single base pair change in proline biosynthesis genes causes osmotic stress tolerance.
AUTOR(ES)
Dandekar, A M
RESUMO
A single base pair change has been found in a site corresponding to a regulatory region of the first enzyme in the proline biosynthetic pathway. This change alters feedback inhibition and is responsible for the synthesis of high levels of proline that enable Escherichia coli to withstand osmotic stress.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=211710Documentos Relacionados
- Recombinant plasmid conferring proline overproduction and osmotic tolerance.
- Characterization of a gamma-glutamyl kinase from Escherichia coli that confers proline overproduction and osmotic tolerance.
- A single base-pair change creates a Chi recombinational hotspot in bacteriophage lambda.
- Stress induction of clpC in Bacillus subtilis and its involvement in stress tolerance.
- Osmoprotective compounds in the Plumbaginaceae: a natural experiment in metabolic engineering of stress tolerance.