Arterial Remodeling
Mostrando 1-12 de 77 artigos, teses e dissertações.
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1. Diuretics are Similar to Losartan on Echocardiographic Target-Organ Damage in Stage I Hypertension. PREVER-Treatment Study
Resumo A terapia de redução da pressão arterial (PA) melhora os parâmetros do ventrículo esquerdo (VE) na lesão a órgãos-alvo causada pela condição hipertensiva na hipertensão de estágio II; no entanto, se existem ou não diferenças relacionadas à classe de medicamentos nos parâmetros ecocardiográficos de pacientes com hipertensão estágio I
Arq. Bras. Cardiol.. Publicado em: 2019-01
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2. Time-course of health-related adaptations in response to combined training in hypertensive elderly: immune and autonomic modulation interactions
Abstract Aims: This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized
Motriz: rev. educ. fis.. Publicado em: 23/11/2018
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3. Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH), characterized by localized increased arterial blood pressure in the lungs, is a slow developing long-term disease that can be fatal. PAH is characterized by inflammation, vascular tone imbalance, pathological pulmonary vascular remodeling, and right-sided heart failure. Current treatments for PAH are palliative and deve
Braz J Med Biol Res. Publicado em: 18/10/2018
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4. Roles of the ERK1/2 and PI3K/PKB signaling pathways in regulating the expression of extracellular matrix genes in rat pulmonary artery smooth muscle cells
Abstract Purpose: To investigate the mechanisms by which PD98059 and LY294002 interfere with the abnormal deposition of extracellular matrix regulated by connective tissue growth factor (CTGF) of rat pulmonary artery smooth muscle cells (PASMCs). Methods: Rat PASMCs were cultured and separated into a control group. Real-time fluorescence quantitative PCR w
Acta Cir. Bras.. Publicado em: 2017-05
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5. Inactivated Pseudomonas aeruginosa inhibits hypoxia-induced pulmonary hypertension by preventing TGF-β1/Smad signaling
Pseudomonas aeruginosa is one of the common colonizing bacteria of the human body and is an opportunistic pathogen frequently associated with respiratory infections. Inactivated P. aeruginosa (IPA) have a variety of biological effects against inflammation and allergy. Transforming growth factor-β (TGF-β) signaling plays a critical role in the regulation of
Braz J Med Biol Res. Publicado em: 25/08/2016
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6. Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells
To understand the pathophysiological mechanisms of pulmonary arterial smooth muscle cell (PASMC) proliferation and extracellular-matrix accumulation in the development of pulmonary hypertension and remodeling, this study determined the effects of different doses of adrenomedullin (ADM) and adrenotensin (ADT) on PASMC proliferation and collagen synthesis. The
Braz J Med Biol Res. Publicado em: 10/12/2013
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7. Estudo morfoquantitativo da parede da parte ascendente da aorta de ratos wistar idosos treinados em natação na intensidade do limiar de lactato
O envelhecimento está associado à elevação da pressão arterial sistólica, ao aumento da parede do ventrículo esquerdo e também, a uma maior rigidez na túnica íntima e média das artérias devido a diferentes fatores, como a destruição das fibras elásticas. Como forma de prevenir doenças cárdio - vasculares, promover mudanças na estrutura das
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/12/2011
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8. Influência da integridade dos barorreceptores nos ajustes morfofuncionais cardíacos à hipertensão espontânea em ratos / Influence of baroreceptor integrity on cardiac morpho-functional adjustments to spontaneous hypertension in rats
It has been demonstrated that reduced baroreflex sensitivity is an independent marker of mortality risk. The arterial baroreflex plays an important role in the maintenance of the moment-to-moment stability of blood pressure (BP). Although the contribution of blood pressure variability (BPV) to cardiovascular morbidity and mortality is well established, the m
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/07/2011
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9. Cardiac and renal effects induced by different exercise workloads in renovascular hypertensive rats
We examined the effect of exercise training (Ex) without (Ex 0%) or with a 3% workload (Ex 3%) on different cardiac and renal parameters in renovascular hypertensive (2K1C) male Fisher rats weighing 150-200 g. Ex was performed for 5 weeks, 1 h/day, 5 days/week. Ex 0% or Ex 3% induced similar attenuation of baseline mean arterial pressure (MAP, 119 ± 5 mmHg
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-06
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10. Impacto do uso rápido dos betabloqueadores sobre a mortalidade e remodelamento ventricular na insuficiência cardíaca avançada / Impact of rapid beta-blockers therapy on mortality and ventricular remodeling in advanced heart failure
Fundamento: A terapia com betabloqueadores é fundamental para o tratamento da insuficiência cardíaca congestiva. Entretanto, apesar dos dados que documentam os benefícios dos betabloqueadores, a otimização da dose desses medicamentos durante a hospitalização ainda não foi testada. Objetivos: Avaliar a segurança da efetividade do betabloqueio rápid
Publicado em: 2011
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11. Adaptação oxidativa e funcional progressiva do sistema cardiopulmonar secundária à hipertensão arterial pulmonar em ratos
Pulmonary Arterial Hypertension (PAH) is a disease that affects the pulmonary vessels, essentially pre-capillaries, leading to remodeling of the vascular wall. It is characterized hemodynamic syndrome, which is the increase in pulmonary vascular resistance and right ventricular afterload. A growing body of evidence shows the involvement of oxidative stress i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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12. Alterações cardiovasculares de fêmeas de ratos espontaneamente hipertensos (SHR) relacionadas com a idade / Cardiovascular changes in female spontaneously hypertensive rats (SHR) age-related
Hypertension is a major cause of cardiovascular disorders, and the natural progression of this disease may trigger further changes in the circulatory system. Experimental models are widely used in studies on the changes that occur in the cardiovascular system induced by hypertension. The SHR is the model that most closely matches the human hypertension, as i
Publicado em: 2011