Antineoplastic
Mostrando 13-24 de 242 artigos, teses e dissertações.
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13. Hospital and oncological dental care: a series of cases
RESUMO O atendimento odontológico hospitalar é uma estratégia educativa e assistencial que tem como objetivo intervir, de forma multidisciplinar, no processo saúde-doença de indivíduos vulneráveis, uma vez que a saúde bucal insatisfatória é um fator de risco para infecções locais e sistêmicas. Pacientes em tratamento oncológico geralmente apres
RGO, Rev. Gaúch. Odontol.. Publicado em: 12/09/2019
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14. Reações adversas a medicamentos no sistema de farmacovigilância do Brasil, 2008 a 2013: estudo descritivo
Resumo: Analisam-se as suspeitas de reações adversas a medicamentos notificadas no sistema de farmacovigilância do Brasil (Notivisa-medicamento) entre 2008 e 2013. Trata-se de estudo descritivo cujas unidades de análises da base de dados foram as notificações e os pares medicamento-reação adversa. Foi identificado um total de 26.554 notificações, o
Cad. Saúde Pública. Publicado em: 22/08/2019
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15. Antineoplastic Effect of Procyanidin-rich Extract of Lafoensia Pacari in Lung Carcinoma Cells
Abstract Lafoensia pacari A. St. Hill has been used in traditional medicine as an anti-ulcerogenic and anti-inflammatory. Although there is an ethnopharmacological indication for cancer treatment, only a few studies have demonstrated its possible anticancer activity. Thus, the aims of this study were: (1) to evaluate the antineoplastic effect of L. pacari et
Braz. arch. biol. technol.. Publicado em: 01/08/2019
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16. Protective effect of gallic acid against cisplatin-induced ototoxicity in rats
Resumo Introdução: A cisplatina é um agente antineoplásico amplamente usado no tratamento de vários tipos de câncer. A ototoxicidade é um dos principais efeitos colaterais que restringem o uso da cisplatina. Objetivo: O objetivo deste estudo foi investigar a eficácia protetora do ácido gálico, em termos bioquímicos, funcionais e histopatológico
Braz. j. otorhinolaryngol.. Publicado em: 10/07/2019
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17. Diseases, conditions, and drugs associated with cicatricial ectropion
RESUMO O ectrópio cicatricial pode ser uma consequência de certas doenças sistêmicas, bem como o resultado do uso de drogas. Nosso objetivo aqui foi pesquisar as diferentes causas desta condição, conforme relatado na literatura, incluindo mais recentemente suspeitas de etiologias. Uma pesquisa bibliográfica detalhada do PubMed indicou que muitas etiol
Arq. Bras. Oftalmol.. Publicado em: 20/05/2019
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18. Antineoplastic therapy administration: Nursing intervention in the relief of suffering
RESUMO Objetivo: Identificar intervenções de enfermagem com o potencial de atuar sobre o sofrimento e avaliar os resultados da intervenção de enfermagem criada. Método: Uma abordagem de estudo multimétodo foi utilizada. Após identificar as evidências científicas e encontrar a teoria de apoio, o processo de intervenção para aliviar o sofrimento d
Rev. Bras. Enferm.. Publicado em: 2019-02
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19. Antineoplastic potential of the aqueous crude extract of Eugenia uniflora L. in human cervical cancer
Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described. In this study, we investigated the biologicals effects
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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20. Hepatic protective effect of grape seed proanthocyanidin extract against Gleevec-induced apoptosis, liver Injury and Ki67 alterations in rats
ABSTRACT Gleevec (imatinib) is an antineoplastic chemotherapeutic agent used in the treatment of many types of cancer. The current study was conducted to examine the possible modifying effects of grape seeds proanthocyandins extract (GSPE) against apoptosis, liver injury and Ki67 alterations induced by Gleevec in male rats. 40 male albino rats were equally d
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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21. Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location
Abstract: The aim of this study was to evaluate the health-related quality of life (QOL) of patients with squamous cell carcinoma (SCC) according to tumor location. The sample consisted of 27 patients with primary SCC in the oral cavity (n = 15), pharynx (n = 7), and larynx (n = 5) who were undergoing cancer treatment at the Cancer Hospital of Londrina, rega
Braz. oral res.. Publicado em: 18/12/2017
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22. Arginine enzymatic deprivation and diet restriction for cancer treatment
ABSTRACT Recent findings in amino acid metabolism and the differences between normal, healthy cells and neoplastic cells have revealed that targeting single amino acid metabolic enzymes in cancer therapy is a promising strategy for the development of novel therapeutic agents. Arginine is derived from dietary protein intake, body protein breakdown, or endogen
Braz. J. Pharm. Sci.. Publicado em: 26/10/2017
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23. Suzuki-Miyaura Coupling between 3-Iodolawsone and Arylboronic Acids. Synthesis of Lapachol Analogues with Antineoplastic and Antileishmanial Activities
A series of 2-hydroxy-3-arylnaphthalene-1,4-diones (3-aryllawsones) were synthesized by Suzuki-Miyaura cross coupling reaction of 3-iodolawsone with arylboronic acids/esters. The hydroxylated resulting products were transformed into their corresponding N,N-diethyl carbamates. The antineoplastic and antileishmanial activities of the compounds were evaluated a
J. Braz. Chem. Soc.. Publicado em: 2017-08
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24. Interleukin-27 augments the inhibitory effects of sorafenib on bladder cancer cells
Both sorafenib and interleukin-27 (IL-27) are antineoplastic drugs. This study aimed to investigate the synergistic effect of these two drugs on bladder cancer cells. HTB-9 and T24 cells were stimulated with IL-27 (50 ng/mL), sorafenib (2 μM) or the synergistic action of these two drugs. The cells without treatment acted as control. Cell proliferation, apop
Braz J Med Biol Res. Publicado em: 20/07/2017