Anti Thyroid Drugs
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Consensus on the diagnostic and therapeutic management of chronic spontaneous urticaria in adults - Brazilian Society of Dermatology
Abstract: Background: Urticarias are frequent diseases, with 15% to 20% of the population presenting at least one acute episode in their lifetime. Urticaria are classified in acute ( ≤ 6 weeks) or chronic (> 6 weeks). They may be induced or spontaneous. Objectives: To verify the diagnostic and therapeutic recommendations in chronic spontaneous urticaria
An. Bras. Dermatol.. Publicado em: 03/06/2019
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2. TSH reference values in the first trimester of gestation and correlation between maternal TSH and obstetric and neonatal outcomes: a prospective Brazilian study
ABSTRACT Objective To define the normal range of TSH in the first trimester of gestation and to evaluate the correlation between maternal TSH and obstetric and neonatal outcomes. Subjects and methods Prospective study. Women without known or clinically suspected thyroid disease and without risk factors for thyroid dysfunction, who became pregnant spontan
Arch. Endocrinol. Metab.. Publicado em: 16/02/2016
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3. Characterization of the clinical and pathological changes in dogs with methimazole-induced hypotyroidism / Caracterização de alterações clínico-patológicas de cães com hipotireoidismo induzido por metimazol
Os distúrbios da tireóide em cães têm se apresentado cada vez mais freqüentes na rotina clínica veterinária, principalmente no que se refere ao hipotireoidismo. Considerando a necessidade de estudar particularidades referentes às alterações clínicas do hipotireoidismo induzido iatrogenicamente em cães, novos e mais aprofundados estudos sobre este
Publicado em: 2006
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4. AvaliaÃÃo da radioiodoterapia com doses de 10 e 15 mCi em pacientes com doenÃas de graves
The hyperthyroidism of Gravesâ disease, the most common form of hyperthyroidism, is caused by autoantibodies that activate the TSH receptor. It is associated with an increase in cardiovascular mortality and hip fractures in elderly females. The treatment options currently available are the antithyroid drugs, surgery and radioiodine, none of which is conside
Publicado em: 2006
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5. Comparative study of Hepatitis C virus genotypes 1 and 3 in Salvador, Bahia
Hepatitis C virus displays a high degree of genetic mutation, with considerable heterogeneity, motivating clinical and biomolecular investigations. It is necessary to understand the effects of genotypes on the course of the disease, as well as their peculiarities at the regional level. OBJECTIVE: The study objective was to compare epidemiological, biochemica
Brazilian Journal of Infectious Diseases. Publicado em: 2003-12
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6. Effect of iodide on Fas, Fas-ligand and Bcl-w mRNA expression in thyroid of NOD mice pretreated with methimazole
Nonobese diabetic (NOD) mice and a derived strain, NOD.H.2h4, have been used as a model for experimental spontaneous thyroiditis and thyroiditis induced by iodide excess after a goiter-inducing period. Some authors have proposed that iodide, given after methimazole or propylthiouracil, is capable of inducing apoptosis in thyroid cells and that anti-thyroid d
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-03
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7. O uso previo de drogas anti-tiroidianas interfere na eficacia da radioiodoterapia na doença de graves?
Pretreatment with thionamides has been implicated in a reduced therapeutic effectiveness of radioiodine in thyrotoxicosis. In order to assess a difference between propylthiouracil(PTU) and methimazol e(MTZ) over patient s outcome, we examined 100 Graves disease patients 3, 6, 9 and 12 months after a 10 mCi standard single dose of 131I . They were assigned to
Publicado em: 2001
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8. Thymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus.
Thymic size and density were studied in 23 untreated patients with Graves' disease and 38 control subjects using computed tomography. Both thymic size and density were higher in untreated patients with Graves' disease than in control subjects in the age-matched group. After treatment with antithyroid drugs, both thymic size and density were significantly red
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9. A class of plant glycosyltransferases involved in cellular homeostasis
Many small lipophilic compounds in living cells can be modified by glycosylation. These processes can regulate the bioactivity of the compounds, their intracellular location and their metabolism. The glycosyltransferases involved in biotransformations of small molecules have been grouped into Family 1 of the 69 families that are classified on the basis of su
Nature Publishing Group.
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10. Hashimoto's thyroiditis and polyarthritis: a possible subset of seronegative polyarthritis.
Fifteen patients presenting with inflammatory polyarthritis who had Hashimoto's thyroiditis were investigated. Only 2/15 had frank myxoedema, 8/15 had incipient hypothyroidism (raised levels of thyrotropin or early symptoms of mild hypothyroidism), and 5/15 were euthyroid (thyrotropin levels normal). The presence or absence of rheumatoid factor (RF) distingu
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11. The Drug of Abuse γ-Hydroxybutyrate Is a Substrate for Sodium-Coupled Monocarboxylate Transporter (SMCT) 1 (SLC5A8): Characterization of SMCT-Mediated Uptake and Inhibition
γ-Hydroxybutyric acid (GHB), a drug of abuse, is a substrate of monocarboxylate transporters (MCTs). Sodium-coupled monocarboxylate transporter 1 (SMCT1; SLC5A8) is expressed in kidney, thyroid gland, neurons, and intestinal tract and exhibits substrate specificity similar to that of the proton-dependent MCT (SLC16A) family. The role of SMCT1 in GHB dis
American Society for Pharmacology and Experimental Therapeutics.
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12. Influence of methimazole on murine thyroiditis. Evidence for immunosuppression in vivo.
Thionamide drugs are immunosuppressives in vitro. To examine this action in vivo, A/J mice were immunized with human thyroglobulin (hTg) (0.5 mg intraperitoneal injections for 5 d) beginning on days 6, 24, and 43 with or without methimazole (M) (0.05%) and l-thyroxine (T4) (0.1 micrograms/ml to prevent thyroid hypertrophy) in their water supply. Groups (n =