Amylase Inhibition
Mostrando 13-24 de 85 artigos, teses e dissertações.
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13. Ferulic acid lowers body weight and visceral fat accumulation via modulation of enzymatic, hormonal and inflammatory changes in a mouse model of high-fat diet-induced obesity
Previous studies have reported on the glucose and lipid-lowering effects of ferulic acid (FA) but its anti-obesity potential has not yet been firmly established. This study investigated the possible anti-obesitogenic effects of FA in mice fed a high-fat diet (HFD) for 15 weeks. To assess the antiobesity potential of FA, 32 male Swiss mice, weighing 20–25 g
Braz J Med Biol Res. Publicado em: 05/01/2017
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14. Purification and characterization of extracellular α-amylase from a thermophilic Anoxybacillus thermarum A4 strain
ABSTRACT α-Amylase from Anoxybacillus thermarum A4 was purified using ammonium sulphate precipitation and Sephadex G-100 gel filtration chromatography, with 29.8-fold purification and 74.6% yield. A4 amylase showed best performance for soluble potato starch hydrolysis at 70 °C and pH 5.5-10.5. A4 amylase was extremely stable at +4 °C, and the enzyme retai
Braz. arch. biol. technol.. Publicado em: 01/12/2016
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15. Metanolic extract of Malpighia emarginata bagasse: phenolic compounds and inhibitory potential on digestive enzymes
ABSTRACT Adding value to fruit residues is of great interest, since they can be presented as a viable solution in search of new drugs for the treatment of obesity and related diseases, due to bioactive substances, especially phenolic compounds. Thus, the objective of this study was to prepare the methanol extract of acerola bagasse flour, in order to evaluat
Rev. bras. farmacogn.. Publicado em: 2016-04
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16. Diplotaxis simplex suppresses postprandial hyperglycemia in mice by inhibiting key-enzymes linked to type 2 diabetes
Abstract Nutritional properties of Diplotaxis simplex Spreng., Brassicaceae, an edible wild cruciferous largely distributed in North Africa, were investigated. Potassium (3690–3780 mg/100 g) and calcium (900–1170 mg/100 g) were the most concentrated minerals. Linoleinic acid was found to be the main fatty acid (25.4–27.7%), followed by palmitic acid (1
Rev. bras. farmacogn.. Publicado em: 2015-04
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17. Phenolic content, antioxidant activity and antiamylolytic activity of extracts obtained from bioprocessed pineapple and guava wastes
The relationship between phenolic content, antioxidant and antiamylolytic activities was investigated in Rhizopus oligosporus-mediated solid-state bioprocessing of pineapple and guava residues. Two different treatments of fruit residues mixed with soy flour (5g of soy flour and 5g of fruit residue; 1g of soy flour and 9g of fruit residue) were inoculated and
Brazilian Journal of Chemical Engineering. Publicado em: 2012-03
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18. ESTUDO DO POTENCIAL TERAPÊUTICO DOS TRITERPENOS PENTACÍCLICOS ÁCIDO BETULÍNICO, ÁCIDO OLEANÓLICO E ÁCIDO URSÓLICO NO TRATAMENTO DA OBESIDADE EM CAMUNDONGOS / STUDY OF THE THERAPEUTIC POTENTIAL OF pentacyclic triterpenes betulinic acid, oleanolic acid and ursolic acid IN THE TREATMENT OF OBESITY IN MICE
Obesity is a global epidemic with an increasing prevalence in both developed and developing countries. It is associated with considerable burden of ill health and an increased risk for coronary artery disease and metabolic syndrome. The rich potential of nature for obesity treatment has not yet been fully explored, although scientific studies suggested the b
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2011
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19. Estudo das características físico-químicas e funcionalidade de bagaços de frutas tropicais desidratados em leito de jorro / Physical-chemical characterization and functionality of dried tropical fruit wastes obtained by using the spouted bed drier
Fruits are rich sources of bioactive compounds, including phenolic compounds. Tropical fruit cultivation is an important productive segment in Brazilian Northeast. Its industrialization generates solid wastes as co-products, with potential environmental impact. Considering the recognized bioactive content of fruit and its derivatives, this research has the o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2011
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20. Inhibition of pancreatic lipase by extracts of Baccharis trimera (Less.) DC., Asteraceae: evaluation of antinutrients and effect on glycosidases
In order to confirm the traditional use of Baccharis trimera (Less.) DC., Asteraceae, for the reduction of weight, plant extracts were evaluated on the activity of pancreatic lipase (PL), an enzyme responsible for hydrolysis of triacylglycerols in the diet for its subsequent absorption. The aqueous and infused extracts did not show inhibitory activity on the
Revista Brasileira de Farmacognosia. Publicado em: 01/04/2011
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21. Mutants of common bean alpha-amylase inhibitor-2 as an approach to investigate binding specificity to alpha-amylases.
Despite the presence of a family of defense proteins, Phaseolus vulgaris can be attacked by bruchid insects resulting in serious damage to stored grains. The two distinct active forms of a-amylase inhibitors, a-AI1 and a-AI2, in P. vulgaris show different specificity toward a-amylases. Zabrotes subfasciatus a-amylase is inhibited by a-AI2 but not by a-AI1. I
Pesquisa Agropecuária Brasileira. Publicado em: 2011
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22. Mutants of common bean alpha-amylase inhibitor-2 as an approach to investigate binding specificity to alpha-amylases.
Despite the presence of a family of defense proteins, Phaseolus vulgaris can be attacked by bruchid insects resulting in serious damage to stored grains. The two distinct active forms of a-amylase inhibitors, a-AI1 and a-AI2, in P. vulgaris show different specificity toward a-amylases. Zabrotes subfasciatus a-amylase is inhibited by a-AI2 but not by a-AI1. I
Pesquisa Agropecuária Brasileira. Publicado em: 2011
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23. Estresse salino e mobilizaÃÃo de reservas cotiledonares durante a germinaÃÃo e estabelecimento da plÃntula de cajueiro anÃo-precoce / Salt stress and reserve mobilization in cotyledons during germination and seedling establishment of precocious-dwarf cashew
This study aimed to obtain basic information on seed germination and seedling establishment of dwarf-precocious cashew (Anacardium occidentale L.) under saline conditions and the relationship between salinity and reserve mobilization during these processes. BRS 189 seeds (cashew nuts) were sown in plastic trays containing vermiculite moistened with distilled
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2009
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24. As Enzimas presentes no trato digestivo dos insetos : um alvo susceptível de inibição
Seeds of scarlet runner bean (Phaseolus coccineus L.) were analyzed for -amylase inhibitor (-AI) activity. By using polyclonal antibodies raised against pure a−AI-1 from common bean (Phaseolus vulgaris L.) it was possible to detect the typical -AI polypeptides (Mr 14 -18 kDa) as well as a large polypeptide of Mr 32,000 Da. Differential inhibition curve
Publicado em: 2009