Amelogenin
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Amelogenin gene influence on enamel defects of cleft lip and palate patients
The aim of this study was to investigate the occurrence of mutations in the amelogenin gene (AMELX) in patients with cleft lip and palate (CLP) and enamel defects (ED). A total of 165 patients were divided into four groups: with CLP and ED (n=46), with CLP and without ED (n = 34), without CLP and with ED (n = 34), and without CLP or ED (n = 51). Genomic DNA
Braz. oral res.. Publicado em: 21/08/2014
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2. Extração de DNA para a análise da amelogenina em amostras fixadas em formalina, incluídas em parafina e arquivadas por 1 e 5 anos no Departamento de Patologia da Universidade Federal de São Paulo. / DNA extraction for amelogenin analysis in formalin fixed, paraffin embedded samples stored for 1 and 5 years from Department of Pathology of Federal University of São Paulo.
Tecidos fixados em formalina e incluídos em parafina permitem investigações retrospectivas valiosas para estudos moleculares, especialmente em estudos genéticos, nos casos em que o DNA não se encontra disponível em amostras congeladas e/ou frescas. Entretanto, de acordo com alguns autores, é difícil obter um DNA de boa qualidade, uma vez que o proces
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2012
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3. Análise da amelogenina pulpar para determinação do gênero biológico / Analysis of pulpar amelogenin for biological gender determination
O processo de identificação humana envolve diferentes etapas, contexto no qual se faz necessário o aprimoramento das técnicas tradicionais e o desenvolvimento de novas metodologias aplicáveis na rotina da prática pericial. É através da investigação do gênero biológico, precedida da determinação da espécie, que se dá o passo inicial no delinea
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/01/2012
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4. Análise molecular de amostras fecais de uma população de veado-mateiro (Mazama americana) para a obtenção de informações genéticas e ecológicas / Molecular analysis of faecal samples of a red brocket deer (Mazama americana) population for obtaining genetic and ecological information
Mazama genus is composed by five species in Brazil. All of them are difficult to observe due to their evasive behaviors, what makes the captures and behavioral studies almost impossible. Thus, the use of non invasive methodologies is necessary to study the ecology and genetics of these species. The fecal DNA analysis is one of the most promising techniques f
Publicado em: 2010
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5. InvestigaÃÃo cromossÃmica e molecular em pacientes com sÃndrome de Turner
A sÃndrome de Turner (ST) que resulta de uma alteraÃÃo cromossÃmica caracterizada pela perda parcial ou total do segundo cromossomo sexual. Essa sÃndrome afeta exclusivamente o sexo feminino, possuindo como principais alteraÃÃes clÃnicas a baixa estatura, disgenesia gonadal, atraso no desenvolvimento das caracterÃsticas sexuais secundÃrias feminina
Publicado em: 2008
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6. Effects of genetic and environmental alterations on the birefringence of dental enamel organic matrix / Efeitos de alterações geneticas e ambientais sobre a birrefringencia da matriz organica do esmalte dentario
O esmalte envolve a porção coronária dos dentes e constitui a estrutura mais mineralizada do corpo vertebrado. Seu desenvolvimento tem início com secreção, processamento proteolítico e auto-agregação de uma complexa mistura de proteínas. O estabelecimento de uma matriz orgânica ordenada parece ser fundamental para a formação adequada da fase min
Publicado em: 2008
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7. Ultrastructural and immunohistochemical study of the influence of fluoride excess on the development of rat incisor tooth buds
Little information is available on the pathogenesis of fluorosis during the fetal and initial postnatal period. In the present study, female rats received 0 (control), 7 or 100 ppm of sodium fluoride in drinking water, one week before breeding and throughout gestation and nursing periods. The hemimandibles of the offspring were collected at 0, 7 and 14 days
Journal of Applied Oral Science. Publicado em: 2007-08
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8. Estudo morfológico ultraestrutural e imuno-histoquímico da influência do excesso de flúor no desenvolvimento do germe dental de incisivo de rato / Morphological ultrastructural and immunohistochemical study of the fluorine excess influence on rat incisor tooth germ development
The dental fluorosis is a result of fluorine toxicity during odontogenesis. Several experimental models have been used in attempt to explain the fluorine pathogenesis in enamel, but during the fetal or the initial postnatal period, there is not much information about its action. For this reason, in this research, the female rats received 0, 7 or 100 ppm of s
Publicado em: 2006
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9. Identification and characterization of amelogenin genes in monotremes, reptiles, and amphibians
Two features make the tooth an excellent model in the study of evolutionary innovations: the relative simplicity of its structure and the fact that the major tooth-forming genes have been identified in eutherian mammals. To understand the nature of the innovation at the molecular level, it is necessary to identify the homologs of tooth-forming genes in other
The National Academy of Sciences.
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10. Construction and identification of mouse amelogenin cDNA clones.
The determination of the biochemical phenotype of tooth epithelium requires specification by the dental mesenchyme. This is a general feature of epithelial-mesenchymal interaction in a number of different epidermal organ systems (e.g., salivary gland, mammary gland, feather, skin, and hair morphogenesis). To investigate these developmental processes, we have
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11. Role of 20-kDa Amelogenin (P148) Phosphorylation in Calcium Phosphate Formation in Vitro*
The potential role of amelogenin phosphorylation in enamel formation is elucidated through in vitro mineralization studies. Studies focused on the native 20-kDa porcine amelogenin proteolytic cleavage product P148 that is prominent in developing enamel. Experimental conditions supported spontaneous calcium phosphate precipitation with the initial formation o
American Society for Biochemistry and Molecular Biology.
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12. A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo.
Ribozymes are small RNA structures capable of cleaving RNA target molecules in a catalytic fashion. Designed ribozymes can be targeted to specific mRNAs, blocking their expression without affecting normal functions of other genes. Because of their specific and catalytic mode of action ribozymes are ideal agents for therapeutic interventions against malfuncti