Adrenergic Antagonists
Mostrando 1-12 de 168 artigos, teses e dissertações.
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1. Antidiarrheal effect of extract from the bark of Combretum leprosum in mice
Abstract This study investigated the effects of the ethanolic extract from the bark of Combretum leprosum (ECL) on intestinal transit and castor-oil induced diarrhea in mice. The oral administration of ECL (750 and 1000 mg/kg) slowed intestinal transit (ID50 of 455 mg/kg). The ECL (250-1000 mg/kg) reduced castor-oil induced diarrhea, in a time- and dose-depe
An. Acad. Bras. Ciênc.. Publicado em: 17/12/2018
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2. Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II
It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (∝1- and β-) receptors (AR) belong to the G-proteins superfamily, which signaling promote glycogen breakdown a
Braz J Med Biol Res. Publicado em: 14/11/2018
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3. Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
This relatively short review demonstrates the very important role of the structures of the natural products adrenaline and relatives, in the design and subsequent approval of β-agonists and antagonists, and of modified nucleosides as anticancer, and in particular, antiviral agents against herpes (HSV), human immunodeficiency virus (HIV) and hepatitis C viru
J. Braz. Chem. Soc.. Publicado em: 2016-08
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4. Antinociceptive effect of semi-purified petroleum ether partition of Muntingia calabura leaves
ABSTRACT Muntingia calabura L., Muntingiaceae, is a medicinal plant for various pain-related diseases. The aims of the present study were to determine the antinociceptive profile and to elucidate the possible mechanisms of antinociception of petroleum ether partition obtained from crude methanol extract of M. calabura leaves using various animal models. The
Rev. bras. farmacogn.. Publicado em: 2016-08
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5. Role of adenylyl cyclase in reduced β-adrenoceptor-mediated vasorelaxation during maturation
Beta-adrenergic receptor (βAR)-dependent blood vessel relaxation is impaired in older animals and G protein activation has been suggested as the causative mechanism. Here, we investigated the role of βAR subtypes (β1AR, β2AR, and β3AR) and cAMP in maturation-dependent vasorelaxation impairment. Aortic rings from 15 Sprague-Dawley male rats (3 or 9 weeks
Braz J Med Biol Res. Publicado em: 04/07/2016
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6. Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats
There is evidence for participation of peripheral β-adrenoceptors in delayed liquid gastric emptying (GE) induced in rats by dipyrone (Dp), 4-aminoantipyrine (AA), and antipyrine (At). The present study aimed to determine whether β-adrenoceptors are involved in delayed GE induced by phenylpyrazole derivatives and the role of the prevertebral sympathetic ne
Braz J Med Biol Res. Publicado em: 02/02/2016
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7. Effect of alpha1-blockers on stentless ureteroscopic lithotripsy
ABSTRACT Objective To evaluate the clinical efficiency of alpha1-adrenergic antagonists on stentless ureteroscopic lithotripsy treating uncomplicated lower ureteral stones. Materials and Methods From January 2007 to January 2013, 84 patients who have uncomplicated lower ureteral stones treated by ureteroscopic intracorporeal lithotripsy with the holmium
Int. braz j urol.. Publicado em: 2016-02
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8. The use of alpha-1 adrenergic blockers in children with distal ureterolithiasis: a systematic review and meta-analysis
Introduction: Urinary lithiasis is the main urologic cause of emergency treatment in adult patient. In the past years, the incidence in children population has increased. However, literature about the use of alpha-1 adrenergic blockers in pediatric population with distal ureterolithiasis is still scarce. The drug acts by decreasing ureter contractions, espe
Int. braz j urol.. Publicado em: 2015-12
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9. Role of α2-adrenoceptors in the lateral parabrachial nucleus in the control of body fluid homeostasis
Central α2-adrenoceptors and the pontine lateral parabrachial nucleus (LPBN) are involved in the control of sodium and water intake. Bilateral injections of moxonidine (α2-adrenergic/imidazoline receptor agonist) or noradrenaline into the LPBN strongly increases 0.3 M NaCl intake induced by a combined treatment of furosemide plus captopril. Injection of mo
Braz J Med Biol Res. Publicado em: 10/01/2014
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10. Effects of atropine and propranolol on lung inflammation in experimental envenomation: comparison of two buthidae venoms
Background Previous works had shown that scorpion venom induced neurotransmitter elevation and an inflammatory response associated with various anatomo-pathological modifications. The most dangerous scorpions species in Algeria responsible for these effects are Androctonus australis hector (Aah) and Androctonus amoreuxi (Aam). Results Comparison of the phys
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 09/04/2013
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11. Avaliação dos efeitos do betabloqueador nebivolol sobre o peritônio em modelo experimental murino de diálise peritoneal / Assessment of the effects of beta-blocker nebivolol on the peritoneum in an experimental murine model of peritoneal dialysis
A falência de ultrafiltração (UFF) é uma causa importante de interrupção da diálise peritoneal (DP) enquanto terapia renal substitutiva. Além da inflamação crônica e aguda causadas à membrana peritoneal (MP) pelos produtos de degradação da glicose, produtos avançados da glicosilação, pH ácido das soluções e infecções, -bloqueadores (BB)
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/10/2011
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12. Efeito da tansulosina e do nifedipino na eliminação de fragmentos após litotripsia extracorpórea por ondas de choque em pacientes com cálculos renais: estudo prospectivo, duplo-cego e randomizado / Effect of tamsulosin and nifedipine on the clearance of fragments after extracorporeal shock waves lithotripsy in patients with kidney stones - a prospective, double-blind and randomized study
Purpose: We evaluated the effects of the adjuvant use of tamsulosin and nifedipine after extracorporeal shock wave lithotripsy (SWL) for 5-20 mm kidney stones. Materials and Methods: We conducted a randomized double-blind trial involving 136 patients with radiopaque kidney stones between 2006 and 2009. Patients were divided into three groups to receive daily
Publicado em: 2011