Adenosine Deaminase
Mostrando 1-12 de 364 artigos, teses e dissertações.
-
1. Pleural tuberculosis: experiences from two centers in Brazil
Abstract Objective: This study aimed to describe the clinical and laboratory findings of patients diagnosed with pleural tuberculosis at two hospitals in southern Brazil. Methods: Patients aged < 18 years were evaluated retrospectively. The patients’ medical and epidemiological history, tuberculin skin test results, radiological and pathological findings
Jornal de Pediatria. Publicado em: 2022
-
2. A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge
Abstract The prognosis of tuberculous meningitis, a rare form of extrapulmonary tuberculosis, depends on the stage of treatment initiation. We report a fatal case of tuberculous meningitis. The patient had received successive tumor necrosis factor (TNF) antagonists and abatacept to treat juvenile idiopathic arthritis, with negative results for polymerase cha
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-09
-
3. The Review of Certain In Vivo Antioxidant Effects on Essential Oils of Origanum Minutiflorum O Schwarz-Ph Davis, Juniperus Excelsa Bieb.subsp. Excelsa and Histopathologic Changes
ABSTRACT Essential oil of plants called Juniperus excelsa Bieb. (JE), Origanum minutiflorum O. Schwarz and P.H. Davis (OM) were used in this study. In order to determine experimental doses, LD50 values of essential oils were determined on mice. Taking into consideration the LD30 range, the experimental toxic doses were calculated for each rat (rat/kg). The t
Rev. Bras. Cienc. Avic.. Publicado em: 2017-06
-
4. Growth inhibition of human breast cancer cells and down-regulation of ODC1 and ADA genes by Nepeta binaloudensis
ABSTRACT Nepeta binaloudensis Jamzad, Lamiaceae, is a rare medicinal plant endemic to Iran. In spite of many studies about the chemical constituents and antibacterial effects of this species, no report has been provided about its cytotoxic and anticancer activities. In this study we have evaluated the effects of EtOH 70%, hexane and aqueous extracts of N. bi
Rev. bras. farmacogn.. Publicado em: 2017-02
-
5. Effects of purine nucleotide administration on purine nucleotide metabolism in brains of heroin-dependent rats
ABSTRACT Heroin is known to enhance catabolism and inhibit anabolism of purine nucleotides, leading to purine nucleotide deficiencies in rat brains. Here, we determined the effect of exogenous purine nucleotide administration on purine nucleotide metabolism in the brains of heroin-dependent rats. Heroin was administrated in increasing doses for 9 consecutive
Braz. J. Pharm. Sci.. Publicado em: 2016-12
-
6. Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space
OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram-positive bacterial infections of the pleural space prior to selecting antibiotics. METHODS: A total of 76 pati
Clinics. Publicado em: 2016-05
-
7. Modulatory effect of iron chelators on adenosine deaminase activity and gene expression in Trichomonas vaginalis
Trichomonas vaginalis is a flagellate protozoan that parasitises the urogenital human tract and causes trichomoniasis. During the infection, the acquisition of nutrients, such as iron and purine and pyrimidine nucleosides, is essential for the survival of the parasite. The enzymes for purinergic signalling, including adenosine deaminase (ADA), which degrades
Mem. Inst. Oswaldo Cruz. Publicado em: 23/10/2015
-
8. ATIVIDADE DE ECTOENZIMAS E DE COLINESTERASES E BIOMARCADORES DE ESTRESSE OXIDATIVO EM PACIENTES COM CÂNCER DE PULMÃO / ACTIVITY OF ECTOENZIMAS AND CHOLINESTERASES AND OXIDATIVE STRESS BIOMARKERS IN PATIENTS WITH LUNG CANCER
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world population, which is clearly seen in statistics, is closely related to smoking, and smoking is considered one of the main risk factors that le
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
-
9. Serum adenosine deaminase, catalase and carbonic anhydrase activities in patients with bladder cancer
OBJECTIVES: The relationship between adenosine deaminase and various cancers has been investigated in several studies. However, serum adenosine deaminase activity and carbonic anhydrase and catalase activities in patients with bladder cancer have not previously been reported. Therefore, the aim of this study was to measure serum adenosine deaminase, carbonic
Clinics. Publicado em: 2012-12
-
10. Pleural tuberculosis: is radiological evidence of pulmonary-associated disease related to the exacerbation of the inflammatory response?
OBJECTIVE: Pleural tuberculosis is the most frequently occurring form of extra pulmonary disease in adults. In up to 40% of cases, the lung parenchyma is concomitantly involved, which can have an epidemiological impact. This study aims to evaluate the pleural and systemic inflammatory response of patients with pleural or pleuropulmonary tuberculosis. METHODS
Clinics. Publicado em: 2012-11
-
11. ATIVIDADE DA ADENOSINA DESAMINASE, CONCENTRAÇÃO DE NUCLEOTIDEOS E NUCLEOSIDEO DE ADENINA EM RATOS INFECTADOS COM Trypanosoma evansi / ACTIVITY OF ADENOSINE DEAMINASE, CONCENTRATION OF ADENINE NUCLEOTIDES AND NUCLEOSIDE IN RATS INFECTED WITH Trypanosoma evansi
O sistema purinérgico é conhecido por ser uma via de sinalização importante em diversos tecidos. Entre os componentes desse sistema destacamos a adenosina, um modulador do sistema nervoso central, circulatório e imunológico. A concentração de adenosina no hospedeiro é controlada pela enzima adenosina deaminase (ADA), presentes em tecidos, células e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/12/2011
-
12. Polimorfismo G22A do gene ADA e gene HLA-B*27: ausência de interações epistáticas na espondilite anquilosante.
Espondilite anquilosante, uma doença auto-imune que se caracteriza principalmente por dor axial ou sinovite assimétrica, acomete preferencialmente caucasianos do sexo masculino portadores de pelo menos um alelo do gene HLA-B*27. Genes e polimorfismos localizados fora da região HLA também são apontados como potenciais candidatos à suscetibilidade a doen
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/06/2011