Acylation
Mostrando 13-24 de 338 artigos, teses e dissertações.
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13. 1-(2,4-dichlorophenyl-1H-pyrazoles: Synthesis, Structural Analysis and Interactions with Cannabinoid Receptors CB1 / 1-(2,4-Diclorofenil)-1H-pirazóis: Síntese, Análise Estrutural e Interação com os Receptores Canabinóides CB1
A method to obtain fourteen enones [EtO2CC(O)C(R2)=C(R1)OR, where R = H, Me; R1 = Pr, Ph, 4-MeOC6H4, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-NO2C6H4, Fur- 2-yl; R2 = H; R1,R2 = -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)6-, 3,4-dihydronaphthalen-2-yl] from acylation of acetals with ethyl oxalyl chloride is reported. The cyclocondensation reaction of these substrat
Publicado em: 2010
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14. Acilenaminonas: Síntese e Aplicação na Obtenção de Pirazóis, Pirazolo[3,4-d]piridazinonas e Pirazolo[1,5-a]pirimidinas / Acylenaminones: Synthesis and Application in the Obtaining of Pyrazoles, Pyrazolo[3,4-d]pyridazinones and Pyrazolo[1,5-a]pyrimidines
The regioespecific synthesis of a series of 14 N-acylated enaminones (52-88%) from the acylation reaction of secondary -enamino ketones [RC(O)CH=CHNR1R2; R = Ph, 4- FC6H4, 4-NO2C6H4, thien-2-yl, CCl3, CF3; R1 = H; R2 = Bn, Ph, 4-NO2C6H4] with trifluoroacetic anhydride or ethyl oxalyl chloride in pyridine is reported. On the other hand, when tertiary enaminon
Publicado em: 2009
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15. Superabsorbent polymer as nanoreactors for preparation of hematite nanoparticles and application of the prepared nanocatalyst for the Friedel-Crafts acylation
Descrevemos a síntese de nanopartículas (30 nm) puras de α-Fe2O3 empregando um nanopolímero superabsorvente (SANP), por decomposição térmica. O α-Fe2O3 sintetizado foi caracterizado por difração de raios X (DRX), infravermelho com transformada de Furrier (IV-TF), microscopia eletrônica de transmissão (TEM) e termogravimetria (TG). A aplicabilidad
Journal of the Brazilian Chemical Society. Publicado em: 2009
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16. USING OF THE IONIC LIQUIDS IN THE SYNTHESIS OF ENONES AND ENAMINONES / UTILIZAÇÃO DE LÍQUIDOS IÔNICOS NA SÍNTESE DE ENONAS E DE ENAMINONAS
The use of ionic liquids 1-butyl-3-methylimidazolium tetrafluorborate ([BMIM] [BF4]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) as catalytic solvent in the synthesis of 1,1,1-trichloro(fluoro)-3-alken-2-onas [CX3C(O)C(R2)=C(R1)OR] from the reaction of enolethers or acetals with acyl halides is reported. The results obtained in the pres
Publicado em: 2009
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17. OBTENÇÃO QUIMIOSSELETIVA DE TRIALOMETIL-β-DICETONAS VIA REAÇÕES DE ACILAÇÃO DE ACETAIS / QUIMIOSELETIVE OBTENTION OF TRIALOMETHYL-β-DIKETONES FROM ACYLATION REACTIONS OF ACETALS
Este trabalho apresenta um método de acilação de acetais aplicado à obtenção quimioseletiva de trialometil-β-dicetonas, inclusive a partir de acetais derivados de cetonas não simétricas, e com os substituintes funcionalizados. Foram obtidas cinco 1,1,1-trialo-4-metóxi-3-alquen-2-onas inéditas [X3CCOCH=C(OMe)R] as quais foram hidrolisadas até
Publicado em: 2009
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18. Síntese de 1-indanonas através da reação de acilação de Friedel-Crafts intramolecular utilizando NbCl5 como ácido de Lewis
The intramolecular Friedel-Crafts acylation reaction of 3-arylpropanoic acids to give 1-indanones can be effected in good yields under mild conditions (room temperature) by using niobium pentachloride. Our results indicate that NbCl5 acts both as reagent (to transform carboxylic acids into acyl chlorides) and as catalyst in the Friedel-Crafts cyclization.
Química Nova. Publicado em: 2008
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19. USE OF MICROWAVE IRRADIATION IN THE SYNTHESIS OF ENONES AND 4,5-DIHYDRO-1H-PYRAZOLES TRIHALOMETHYL-SUBSTITUTED / USO DE ENERGIA MICROONDAS NA SÍNTESE DE ENONAS E DE 4,5-DIIDROPIRAZÓIS TRIALOMETIL-SUBSTITUÍDOS
The solvent-free microwave-assisted regiospecific synthesis of a series of 5-trihalomethyl-4,5-dihydro-1H-pyrazole (7 - 10) from the cyclocondensation of 1,1,1- trihalo-4-alkoxy-3-alken-2-ones (5 - 6),[ CX3COC(R)2=C(R)1OR, where X = Cl, F; R = Me, Et; R2 = H, Me and R1 = H, Me, Et, Pr, iso-Pr, Bu, iso-Bu, tert-Bu, iso - Pen, Ph, 4-Me-Ph, 4-MeO-Ph, 4-NO2-Ph,
Publicado em: 2008
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20. Estudos metodológicos visando a síntese da biotina a partir da hidantoína
Biotin (1), a member of the vitamin B complex group, has been an attractive synthetic target due to its biological activity and its applications in different fields such as immunology, radiotherapy and bioanalytical chemistry. In this thesis we report some experimental results for an alternative biotin synthesis, using hydantoin (146) as starting material. T
Publicado em: 2008
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21. Aplicações dos heteropoliácidos do tipo Keggin à acilação Friedel-Crafts e à síntese de chalconas. / Applications of the Keggin type heteropolyacids Friedel-Crafts acylation and synthesis of chalcones.
Os heteropoliácidos são polioxometalatos, compostos de um cluster óxido, com prótons associados, apresentando alta acidez de Brönsted, que tem atraído interesse acadêmico e industrial, devido a capacidade de promover catálise verde, atuando como catalisador homogênea e heterogênea. Diversas reações orgânicas já foram conduzidas neste sistema ca
Publicado em: 2008
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22. SÃntese assimÃtrica de 3-carboxamidas enantiomericamente puras e de hidrazidas e arilhidrazonas, derivadas do novo heterociclo 7-(benzoil)- 2-isoxazolina[5,4-b] pirrolidina. AvaliaÃÃo das atividades biolÃgicas
In our previous studies, aza-bicyclic 2-isoxazolines were obtained, such as, 2- isoxazoline[5,4-b] piperidine and 2-isoxazoline[5,4-b] pyrrolidine. N-(benzoyl)-amides and, derived from these heterocycles, showed promising biological activity, (anti-inflammatory and toxicity). Compounds containing hydrazide and hydrazone functionalities are described in the l
Publicado em: 2008
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23. Síntese e estudo das interações de 3-(fosfato)- e 3-(fosfonamida)-4,4,4-trifluor-but-1-il-carbamatos de etila com a enzima acetilcolinesterase e síntese de 3-carboxietil- e 3-pirimidin-2-il-2-oxo-6-trifluormetil-[1,2,3]oxatiazinanas / Synthesis and interactions studies of 3-phosphate- and 3-phosphonamide-4,4,4-trifluoro-but-1-yl-carbamic acid ethyl esters with acetylcholinesterase enzyme and synthesis of 3-carboxyethyl- and 3-pyrimidin-2-yl-2-oxo-6-trifluoromethyl-[1,2,3]oxathiazinanes
A series of [3-(phosphate)-4,4,4-trifluoro-but-1-yl]-carbamic acid ethyl ester and [3-(phosphonamide)-4,4,4-trifluoro-but-1-yl]-carbamic acid ethyl ester obtained from the reaction of g-amino alcohols (4,4,4-trifluoro-3-hydroxy-butan-1-yl)-carbamic acid ethyl ester with phosphorus oxychloride in the presence of base and subsequent reaction with alcohols or a
Publicado em: 2007
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24. Graphite Functionalized in Conditions of Friedel-Crafts Reaction mediated by Radiation of Microwave: New Material for Construction of Electrodes of Carbon Paste / Grafite funcionalizada em condições de Friedel-Crafts mediada por radiação de microondas: novo material para construção de eletrodos de pasta de carbono
Modification and/or functionalization of eletrodic materials have been investigated in order to improve the application of chemically modified electrode (CME) regards on their sensitivity, selectivity and reactivity comparing with unmodified substrate. However, the stability and reproducibility of these CME are one of the most important goals to achieve main
Publicado em: 2007