Acylation
Mostrando 1-12 de 338 artigos, teses e dissertações.
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1. INSIGHT INTO THE CONFORMATIONAL SPACE OF N-BENZYL-N-(FURAN-2-YLMETHYL)ACETAMIDE BY NMR SPECTROSCOPY AND DFT CALCULATIONS
In this study, the conformational behavior of N-benzyl-N-(furan-2-ylmethyl) acetamide in chloroform was addressed by using a combined experimental/theoretical strategy using NMR spectroscopy and quantum chemical calculations. The 1H and 13C one-dimensional NMR spectra, as well as the two-dimensional HSQC-DEPT and HMBC-DEPT NMR spectra, evinced the presence o
Quím. Nova. Publicado em: 2021-01
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2. AN ELECTROCHEMILUMINESCENCE SANDWICH BIOSENSOR FOR THE DETECTION OF LIPOPOLYSACCHARIDE
A novel electrochemiluminescence (ECL) biosensor for the determination of lipopolysaccharide (LPS), a biomarker of endotoxemia, was designed. The nanoprobe (Ru1@SiO2-peptide) with a specific peptide (CIGKLHSAGK) labeled with a carboxyl functionalized Ru@SiO2 (Ru1@SiO2) was prepared by the acylation reaction. The ECL peptide biosensor was obtained by the stro
Quím. Nova. Publicado em: 2020-06
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3. An Acetal Acylation Methodology for Producing Diversity of Trihalomethyl-1,3-dielectrophiles and 1,2-Azole Derivatives
A series of functionalized 1,1,1-trihalo-4-methoxy-3-alken-2-ones [CX3C(O)CR1=CROMe, where X = F or Cl; R = n-heptyl, n-octyl, n-nonyl, n-decyl, n-undecyl, n-tridecyl, (CH2)2CH=C(Me)2, (CH2)2Ph, (CH2)2-(4-HOC6H4), (CH2)2-(4-MeOC6H4), (CH2)2CO2Me, (CH2)3CO2Me, CH(SMe)CH3, CH2(2-MeOC6H4), and R1 = H, and R = H and R1 = n-decyl] were synthesized from respective
J. Braz. Chem. Soc.. Publicado em: 2020-02
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4. Easy and Simple SiO2 Immobilization of Lipozyme CaLB-L: Its Use as a Catalyst in Acylation Reactions and Comparison with Other Lipases
In this study, lipase from Candida antarctica B (Lipozyme CaLB-L) was successfully immobilized on SiO2 through adsorption and used to obtain (R)-(+)-esters derived from (R,S)-1-phenylethanol. The new immobilized enzyme was compared with commercially immobilized lipases (Novozyme 435, Lipozyme 435 and Pseudomonas cepacia (PSC-II and PSD-I)). Lipozyme CaLB-L a
J. Braz. Chem. Soc.. Publicado em: 2017-07
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5. Homocysteine induces glyceraldehyde-3-phosphate dehydrogenase acetylation and apoptosis in the neuroblastoma cell line Neuro2a
High plasma levels of homocysteine (Hcy) promote the progression of neurodegenerative diseases. However, the mechanism by which Hcy mediates neurotoxicity has not been elucidated. We observed that upon incubation with Hcy, the viability of a neuroblastoma cell line Neuro2a declined in a dose-dependent manner, and apoptosis was induced within 48 h. The median
Braz J Med Biol Res. Publicado em: 19/01/2016
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6. SYNTHESIS AND ANTIFUNGAL ACTIVITY OF PALMITIC ACID-BASED NEOGLYCOLIPIDS RELATED TO PAPULACANDIN D
A series of six new palmitic acid-based neoglycolipids related to Papulacandin D were synthesized in five steps, resulting in good yields, and they were evaluated against Candida spp. All twelve synthetic intermediates were also evaluated. The synthesis involved the initial glycosylation of two phenols (4-hydroxy-3-methoxybenzaldehyde and 3-hydroxybenzaldehy
Quím. Nova. Publicado em: 2015-12
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7. ENZYMATIC RESOLUTION OF ANTIDEPRESSANT DRUG PRECURSORS IN AN UNDERGRADUATE LABORATORY
The use of biocatalysts in synthetic chemistry is a conventional methodology for preparing enantiomerically enriched compounds. Despite this fact, the number of experiments in chemical teaching laboratories that demonstrate the potential of enzymes in synthetic organic chemistry is limited. We describe a laboratory experiment in which students synthesized a
Quím. Nova. Publicado em: 2015-02
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8. Degradación in-vitro de mezclas de poliuretano termoplástico y almidón modificado
The chemical structure of the cassava starch was modified by acylation. Cassava starch modified was mixed with urethane prepolymer based on castor oil modified by transesterification (MCO) and isophorone diisocyanate (IPDI) in order to prepare starch-blended thermoplastic polyurethanes. Polyurethanes were exposed to in-vitro degradation then monitored for ch
Polímeros. Publicado em: 07/06/2013
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9. Solventes verdes para biopolímeros: síntese e aplicação de líquidos iônicos na derivatização de celulose / Green solvents for biopolymers: synthesis of ionic liquids and their use in derivatization of cellulose
The work reported has the target of studying the acylation of cellulose under homogeneous reaction conditions. Imidazolium-based ionic Liquids (ILs) were employed as solvents, and the reaction was assisted by a microwave. These following processes have been studied: Optimization of the synthesis of ILs; ii) Effects of the structure of ILs on the dissolution
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/10/2011
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10. Avaliação da capacidade emulsificante de gelatina acilada / Emulsifying capacity evaluation of acylated gelatin
A gelatina é uma proteína de alto interesse e valor comercial, no entanto seu uso como agente emulsificante ainda é bastante restrito devido à limitações tecnológicas. O objetivo geral deste trabalho foi investigar as alterações nas propriedades físicas, químicas e funcionais da gelatina de origem bovina quando submetida à modificação química
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/06/2011
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11. Acilação de Friedel-Crafts do 2-metoxinaftaleno usando o ácido dodecafosfotúngstico suportado em sílica (HPW/SiO2) como catalisador e acetonitrila como solvente
The synthesis of fine chemicals intermediates using Friedel-Crafts acylation is one of the most important methods in chemical technology. In this work, the acylation of 2-methoxynaphthalene with acetic anhydride using a silica-supported dodecatungstophosphoric acid catalyst (HPW/SiO2) and acetonitrila as solvent was studied, showing that this reaction is a f
Química Nova. Publicado em: 2010
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12. Poliuretanos elastoméricos obtenidos a partir de aceite de ricino y almidón de yuca original y modificado con anhídrido propiónico: síntesis, propiedades fisicoquímicas y fisicomecánicas
Chemical modification of cassava starch was conducted through an acylation reaction by using pyridine and propionic anhydride to replace the functional groups of starch. Polyurethane elastomers were prepared using suspensions of the mixture obtained from castor oil and yucca starch that was modified by a propionic anhydride reaction. The suspensions were cha
Química Nova. Publicado em: 2010