Acute Toxicity
Mostrando 49-60 de 514 artigos, teses e dissertações.
-
49. Toxicity and antitumor efficacy of Croton polyandrus oil against Ehrlich ascites carcinoma cells
ABSTRACT The essential oil from Croton polyandrus Spreng., Euphorbiaceae, leaves was tested for the toxicity and antitumor activity. The concentration producing 50% hemolysis was 141 µg/ml on mice erythrocytes. In the acute toxicological study, the estimated LD50 was 447.18 mg/kg. The essential oil did not induce increase in number of micronucleated erythro
Rev. bras. farmacogn.. Publicado em: 2016-12
-
50. Acute Toxicity and Cytotoxicity Effect of Ethanolic Extract of Spondias tuberosa Arruda Bark: Hematological, Biochemical and Histopathological Evaluation
RESUMO Spondias tuberosa Arruda, popularmente conhecida como umbu, é uma espécie nativa da Caatinga amplamente utilizada na medicina popular, cujo perfil toxicológico ainda não é conhecido. Deste modo, este estudo avaliou o perfil fitoquímico, a toxicidade aguda e a citotoxicidade do extrato etanólico da casca da Spondias tuberosa Arruda (EEStb) nos p
An. Acad. Bras. Ciênc.. Publicado em: 10/10/2016
-
51. EVALUATION OF AEROBIC AND ANAEROBIC BIODEGRADABILITY AND TOXICITY ASSESSMENT OF REAL PHARMACEUTICAL WASTEWATER FROM INDUSTRIAL PRODUCTION OF ANTIBIOTICS
Abstract This study evaluates aerobic and anaerobic biodegradability and toxicity of a real pharmaceutical wastewater, which focuses on antibiotics production. Zahn-Wellens and Organization for Economic Cooperation and Development (OECD) methodologies were applied in order to verify the wastewater's biodegradability and Microtox® analysis was performed for
Braz. J. Chem. Eng.. Publicado em: 2016-09
-
52. Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice
RESUMO Os manguezais representam zonas de elevada produtividade biológica sendo uma das regiões mais ricas em substâncias bioativas utilizadas na produção de medicamentos. Conocarpus erectus (Combretaceae) conhecida como mangue botão é uma das espécies encontrada nos manguezais e é utilizada na medicina popular no tratamento de anemia, catarro, conj
An. Acad. Bras. Ciênc.. Publicado em: 04/08/2016
-
53. A subchronic toxicity study of ethanol root extract of baked Aconitum flavum in rats
ABSTRACT The genus Aconitum has strong toxicity, but the acute toxicity of baked Aconitum flavum Hand.-Mazz., Ranunculaceae, was reduced significantly on the premise of keeping anti-inflammatory and anti-nociceptive activities. However, the risk associated with long-term use is unknown. In a sub-chronic toxicity study, rats were orally administered A. flavum
Rev. bras. farmacogn.. Publicado em: 2016-08
-
54. Anti-inflammatory activity and acute toxicity studies of hydroalcoholic extract of Herissantia tiubae
ABSTRACT Hydroalcoholic extract of aerial parts of Herissantia tiubae (K. Schum.) Brizicky, Malvaceae, was evaluated in experimental models of inflammation and toxicity. For toxicity assays, male and female Swiss mice were orally treated with hydroalcoholic extract of H. tiubae (2000 mg/kg) and analyzed by consumption of water and food, body weight, mortalit
Rev. bras. farmacogn.. Publicado em: 2016-04
-
55. REDUCTION OF EXCESS SLUDGE PRODUCTION IN AN ACTIVATED SLUDGE SYSTEM BASED ON LYSIS-CRYPTIC GROWTH, UNCOUPLING METABOLISM AND FOLIC ACID ADDITION
Abstract The following sludge reduction alternatives were tested in wastewater biological reactors: oxic-settling-anaerobic (OSA-process); ultrasonic disintegration (UD); chlorination (CH); 3,3',4',5-tetrachlorosalicylanilide (TCS); and folic acid (FA). Compared to the control system, UD reduced 55% of the sludge production, and greater substrate and nutrien
Braz. J. Chem. Eng.. Publicado em: 2016-03
-
56. Biodistribution, pharmacokinetics and toxicity of a Vasconcellea cundinamarcensis proteinase fraction with pharmacological activity
Abstract Prior studies demonstrate that a proteinase fraction from Vasconcellea cundinamarcensis V.M. Badillo, Caricaceae, exhibits wound healing activity in gastric and cutaneous models and antitumoral/antimetastatic effects. Here, we present the toxicity, pharmacokinetics and biodistribution data for this proteinase fraction following a single dose into Sw
Rev. bras. farmacogn.. Publicado em: 2016-02
-
57. Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest
Abstract The “bacuri” (Platonia insignis Mart., Clusiaceae) is a native tropical fruit from the Brazilian Amazon and Northeast Regions. Its seeds are used to treat inflammatory diseases, diarrhea and skin problems in traditional medical practices. Regarding its widespread medicinal uses, it is important to evaluate the biological and toxicological potent
Rev. bras. farmacogn.. Publicado em: 2016-02
-
58. Dosimetric Coverage of the Prostate, Normal Tissue Sparing, and Acute Toxicity with High-Dose-Rate Brachytherapy for Large Prostate Volumes
ABSTRACT Purpose To evaluate dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with HDR brachytherapy for large prostate volumes.
Materials and Methods One hundred and two prostate cancer patients with prostate volumes >50 mL (range: 5-29 mL) were treated with hig
Int. braz j urol.. Publicado em: 2015-06
-
59. Combined acute interstitial pneumonitis and pancytopenia induced by low-dose methotrexate in a hemodialysis patient treated for bullous pemphigoid
AbstractMethotrexate has been widely used for many years in the treatment of a variety of diseases. Acute pneumonitis and bone marrow suppression are very serious side effects in methotrexate treatment. A 48-year-old man with end-stage renal disease undergoing chronic hemodialysis developed combined acute pneumonitis and pancytopenia after a cumulative dose
An. Bras. Dermatol.. Publicado em: 2015-06
-
60. Anti-inflammatory action of Justicia acuminatissima leaves
AbstractIn Amazonas State (Brazil), Justicia acuminatissima (Miq.) Bremek., Acanthaceae, leaf teas are used in folk medicine to treat several inflammatory illnesses. In order to validate this medicinal application, we analyzed the acute toxicity and antioxidant, antiedematogenic and antinociceptive potentials of an aqueous extract of this species, using cult
Rev. bras. farmacogn.. Publicado em: 2015-06