Acute Toxicity
Mostrando 37-48 de 514 artigos, teses e dissertações.
-
37. Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root extract on the local effects induced by Bothrops jararacussu venom
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararacussu venom (BjuV), antiphospholipasic, antiproteolytic,
Braz J Med Biol Res. Publicado em: 03/12/2018
-
38. Appraisal of acute oral toxicity of glucuronoxylan hydrogel from Mimosa pudica seeds
Glucuronoxylan hydrogel (GXH) isolated from M. pudica seeds was assessed for acute toxicology in albino mice that were alienated into four groups. Three groups, i.e., II, III and IV received GXH at a dose of 1, 2 and 5 g/kg, respectively while group I was retained untreated and provided routine diet. After administering GXH, mice were examined for vomiting,
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
-
39. Essential oil of Pterodon polygalaeflorus Benth attenuates nociception in mice
Essential oils (EO) are volatile liquids responsible for the aroma of plants. Pterodon polygalaeflorus seeds have received widespread use in folk medicine for the treatment of inflammatory diseases. For this reason and because Pterodon polygalaeflorus seeds have great EO content, which is frequently pharmacologically active, the present study aimed to evalua
Braz J Med Biol Res. Publicado em: 04/10/2018
-
40. Assesment of the Genotoxic Effect of the Diazinon on Root Cells of Allium cepa (L.)
ABSTRACT Organophosphorous pesticides (OPs) posses a great potential of acute toxicity for exposed animals and men. To evaluate the toxic potential of the organophosphate diazinon on root meristematic cells of Allium cepa L., was created two groups: In group 1 (control group), was not given any chemical. In group 2 (diazinon-treatment group), different doses
Braz. arch. biol. technol.. Publicado em: 06/08/2018
-
41. Acute toxicity study of a polysaccharide based hydrogel from linseed for potential use in drug delivery system
ABSTRACT Linseed hydrogel (LSH) was evaluated by acute toxicity for its potential application in oral drug delivery design. White albino mice and rabbits were divided in four groups (I-IV) and different doses of LSH (1, 2 and 5 g/kg body weight) were given except to the control group (I) that was left untreated. Rabbits were monitored for eye irritation, acu
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
-
42. Pharmaceutical development of tablets containing a spray-dried optimized extract from Lippia origanoides H. B. K.: influence of excipients and toxicological assessment
ABSTRACT Lippia origanoides is a honey shrub which has showed hypotensive potential assessed by in vivo studies. The aim of this work is the development of a pharmaceutical formulation composed by an optimized extract obtained from aerial parts of L. origanoides. The quantification of the naringenin marker in the dry extract and tablets developed was perform
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
-
43. Comparação dos efeitos das folhas de Cestrum axillare Vell. com as saponinas isoladas em caprinos
ABSTRACT: Cestrum axillare Vell. (formerly Cestrum laevigatum Schltd.), family Solanaceae, is the most important hepatotoxic plant in Brazil that causes acute poisoning. It occurs in the Southeast and Center-West regions and in coastal areas of the Northeast Brazil. Spontaneous poisoning was described in cattle, goats and sheep, with clinical signs evidenced
Pesq. Vet. Bras.. Publicado em: 2018-05
-
44. Antiedematogenic activity of the indole derivative N-salicyloyltryptamine in animal models
ABSTRACT The N-salicyloyltryptamine (NST) is an indole derivative compound analogue to the alkaloid N-benzoyltryptamine. In the present study, the antiedematogenic activity of NST was investigated in animal models. Firstly, the acute toxicity for NST was assessed according to the OECD Guideline no. 423. The potential NST-induced antiedematogenic activity was
An. Acad. Bras. Ciênc.. Publicado em: 2018-03
-
45. In vitro antifungal activity of Myracrodruon urundeuva Allemão against human vaginal Candida species
ABSTRACT Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human vaginal Candida species and evaluate the possible toxicological activities of M. urundeuva. Initially, ethanol extracts, ethyl acetat
An. Acad. Bras. Ciênc.. Publicado em: 24/07/2017
-
46. Acute kidney injury complicating bee stings – a review
ABSTRACT Bee stings can cause severe reactions and have caused many victims in the last years. Allergic reactions can be triggered by a single sting and the greater the number of stings, the worse the prognosis. The poisoning effects can be systemic and can eventually cause death. The poison components are melitin, apamin, peptide 401, phospholipase A2, hyal
Rev. Inst. Med. trop. S. Paulo. Publicado em: 01/06/2017
-
47. Acute amiodarone toxicity causing respiratory failure
Summary A 66-year-old male patient was referred to our clinic with severe pneumonia. Bronchoscopy was performed due to clinical worsening despite antibiotics and diuretic therapy, respiratory failure and radiographic progression. Because bacterial cultures of the bronchoalveolar lavage fluid were negative and after using amiodarone for almost one month, we e
Rev. Assoc. Med. Bras.. Publicado em: 2017-03
-
48. Tilapia (Oreochromis niloticus) as a Biondicator of Copper and Cadmium Toxicity. A Bioavailability Approach
The acute toxicity of copper and cadmium in Oreochromis niloticus was evaluated through a 96 h static assay. Precipitation of Cu and co-precipitation of Cd in the presence of Cu were noted, being indicative of differences in nominal and actual concentrations of metals. Under these conditions, LC50-96h was determined as 3.53 mg L-1Cu, 20.1 mg L-1 Cd and 1.36
J. Braz. Chem. Soc.. Publicado em: 2017-01