Activation Of Macrophages
Mostrando 13-24 de 1249 artigos, teses e dissertações.
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13. Receptor expression and responsiveness of human peripheral blood mononuclear cells to a human cytomegalovirus encoded CC chemokine
Human cytomegalovirus is a ubiquitous pathogen that infects the majority of the world's population. After long period of time co-evolving with human being, this pathogen has developed several strategies to evade host immune surveillance. One of the major trick is encoding homologous to those of the host organism or stealing host cellular genes that have sign
Braz J Infect Dis. Publicado em: 2015-08
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14. BAY 41-2272 activates host defence against local and disseminated Candida albicans infections
In our previous study, we have found that 5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-pyrimidin-4-ylamine (BAY 41-2272), a guanylate cyclase agonist, activates human monocytes and the THP-1 cell line to produce the superoxide anion, increasing in vitro microbicidal activity, suggesting that this drug can be used to modulate immune f
Mem. Inst. Oswaldo Cruz. Publicado em: 23/01/2015
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15. Sympathetic glial cells and macrophages develop different responses to Trypanosoma cruzi infection or lipopolysaccharide stimulation
Nitric oxide (NO) participates in neuronal lesions in the digestive form of Chagas disease and the proximity of parasitised glial cells and neurons in damaged myenteric ganglia is a frequent finding. Glial cells have crucial roles in many neuropathological situations and are potential sources of NO. Here, we investigate peripheral glial cell response to Tryp
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-07
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16. Expression of costimulatory molecules in antigen-activated peritoneal macrophages treated with either ovalbumin or palmitoyl-ova conjugates
One of the mechanisms by which adjuvants are believed to promote T-cell activation and prevent induction of oral tolerance is by up-regulating the expression of co-stimulatory molecules on antigen presenting cells. Mice treated orally with palmitoyl-ovalbumin conjugates become immunized, while those treated with native ovalbumin (Ova) become tolerant. Cells
Braz. arch. biol. technol.. Publicado em: 25/10/2013
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17. Adenovirus-mediated siRNA targeting TNF-α and overexpression of bone morphogenetic protein-2 promotes early osteoblast differentiation on a cell model of Ti particle-induced inflammatory response in vitro
Wear particles are phagocytosed by macrophages and other inflammatory cells, resulting in cellular activation and release of proinflammatory factors, which cause periprosthetic osteolysis and subsequent aseptic loosening, the most common causes of total joint arthroplasty failure. During this pathological process, tumor necrosis factor-alpha (TNF-α) plays a
Braz J Med Biol Res. Publicado em: 2013-10
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18. Pathophysiology of bacterial infection of the central nervous system and its putative role in the pathogenesis of behavioral changes
Invasion of the central nervous system (CNS) by microorganisms is a severe and frequently fatal event during the course of many infectious diseases. It may lead to deafness, blindness, cerebral palsy, hydrocephalus, cognitive impairment or permanent neurological dysfunction in survivors. Pathogens can cross the blood-brain barrier by transcellular migration,
Rev. Bras. Psiquiatr.. Publicado em: 2013-03
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19. Avaliação do papel desenvolvido pelo gene Slc11a1 na ativação de macrófagos durante a indução de respostas inflamatórias. / Role of Slc11a1 gene in macrophage activation during inflammatory response.
O gene Slc11a1 regula a resistência contra S. entérica, L. donovani e M. tuberculosis. Sublinhagens de camundongos AIRmax e AIRmin homozigotas para os alelos R e S do gene Slc11a1 (AIRmax,RR, AIRmaxSS, AIRminRR e AIRminSS) foram utilizadas para avaliar o efeito destes alelos na ativação de macrófagos peritoneais (MF), induzida pelo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/08/2012
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20. EVALUATION OF LEISHMANICIDAL ACTIVITY OF MACROPHAGES ISOLATED FROM TREATED AND ASYMPTOMATIC VISCERAL LEISHMANIASIS SUBJECTS. / AVALIAÇÃO DA ATIVIDADE LEISHMANICIDA DE MACRÓFAGOS ISOLADOS DE INDIVÍDUOS TRATADOS E ASSINTOMÁTICOS PARA LEISHMANIOSE VISCERAL.
As leishmanioses são um grave problema de saúde pública no mundo, demandando medidas eficazes no seu controle e tratamento. A leishmaniose visceral é a forma mais grave e pode ser letal, caso não seja tratada. A depender da interação entre o parasita e a resposta imune do hospedeiro, podem-se desenvolver diferentes manifestações clínicas: forma ass
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2012
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21. Atividade imunomoduladora da ouabaína no processo inflamatório agudo / OUABAIN IMMUNOMODULATORY ACTIVITY IN THE ACUTE INFLAMMATORY PROCESS.
Ouabain (OUA), a potent inhibitor of the Na+,K+-ATPase pump, was identified as an endogenous substance of human plasma. In recent years, ouabain was shown to affect various immunological processes. Mechanisms that involve cellular differentiation, proliferation, activation and migration, as well as inflammatory mediators release, are activated during inflamm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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22. Renal macrophage infiltration is associated with a poor outcome in IgA nephropathy
OBJECTIVES: The objectives of our study were as follows: 1) to analyze the prognostic value of macrophage infiltration in primary IgA nephropathy (IgAN) and 2) to study the relationship between macrophages and other factors associated with the development of renal fibrosis, including mast cells, TGF-β1, α-SMA and NF-kB. METHODS: We analyzed 62 patients who
Clinics. Publicado em: 2012-07
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23. In vitro study of the effect of a probiotic bacterium Lactobacillus rhamnosus against herpes simplex virus type 1
BACKGROUND: Due to the emergence of drug resistance in herpes simplex virus type 1 (HSV-1), researchers are trying to find other methods for treating herpes simplex virus type 1 infections. Probiotic bacteria are effective in macrophage activation and may have antiviral activities. OBJECTIVE: This study aimed at verifying the direct effect of Lactobacillus r
Brazilian Journal of Infectious Diseases. Publicado em: 2012-04
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24. Efeito da ração hiperlipídica e do extrato aquoso de erva-mate (Ilex paraguariensis) sobre a composição corporal e sobre a resposta inflamatória de macrófagos peritoniais de ratos Wistar / Effect of high-fat diet and yerba mate aqueous extract (Ilex paraguariensis) on body composition and on inflammatory response of peritonial macrophages in Wistar rats
Introduction Inflammation is involved in the pathogenesis of metabolic syndrome and non communicable chronic diseases (NCCD). In macrophages, the nuclear transcription factor kappa B (NF-B) controls the gene expression of many inflammatory mediators and its activity can be regulated by several food bioactive compounds. Yerba mate (Ilex paraguariensis) contai
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/09/2011