Acetogenins
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Antileishmanial Acetylene Fatty Acid and Acetogenins from Seeds of Porcelia macrocarpa
In the present work five acetylene derivatives (1-5), including three unknowns (1, 3 and 4), were isolated from seeds of Porcelia macrocarpa (Annonaceae). The structures of isolated compounds were determined as docos-13-yn-21-enoic acid (1), 3-hydroxy-4-methylene-2-(eicos-11’-yn-19’-enyl)but-2-enolide (2), 3-hydroxy-4-methylene-2-(octadec-9’-yn-17’-e
J. Braz. Chem. Soc.. Publicado em: 2021-02
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2. NMR-Based Metabolomic Screening for Metabolites Associated with Resistance to Meloidogyne javanica in Annona muricata Roots
The resistance of Annona muricata roots to the nematode Meloidogyne javanica was investigated by nuclear magnetic resonance (NMR)-based metabolomics in combination with principal component analysis (PCA). Metabolic changes in roots exposed and not exposed to the nematode were evaluated and compared. In addition, the presence of nematicidal compounds in the r
J. Braz. Chem. Soc.. Publicado em: 23/05/2019
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3. Influence of Seasonality and Sunlight Effects on Rollinia mucosa Leaves Fingerprint
Rollinia mucosa fruit has generated great interest due to the presence of bioactive compounds, which exhibit promising biological activities. Fingerprinting analytical techniques, chromatographic-diode array detection (DAD), infrared, mass spectrometric, 1H and 13C nuclear magnetic resonance (NMR) spectra, associated with chemometric analysis and mixture des
J. Braz. Chem. Soc.. Publicado em: 08/04/2019
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4. UPLC–QTOF–MS and NMR analyses of graviola (Annona muricata) leaves
ABSTRACT Graviola leaves (Annona muricata L., Annonaceae) are used by some people to try to treat or even cure cancer, even though over-consumption of the fruit, which contains the neurotoxins annonacin and squamocin has caused an atypical form of Parkinson's disease. In previous analyses, the fruits were extracted with methanol under ambient conditions befo
Rev. bras. farmacogn.. Publicado em: 2016-04
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5. C15 acetogenins from the Laurencia complex: 50 years of research – an overview
Abstract Acetogenins are secondary metabolites derived from the polyketide pathway and their potential role as chemotaxonomical markers for red algae belonging to the Laurencia complex has been long pointed out. C15 acetogenins from algae are quite different from plant acetogenins: they are usually halogenated, and have an enyne or a bromoallene terminal gro
Rev. bras. farmacogn.. Publicado em: 2015-12
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6. Discrimination of Annona muricata and Rollinia mucosa Extracts by Using Multivariate Curve Resolution and Partial Least-Squares Regression of Liquid Chromatography-Diode Array Data
Species of the Annonaceae family are used in traditional medicine, and several antitumor acetogenins have been isolated from the leaves of Annona muricata and Rollinia mucosa. Leaves samples (self-shaded and sun-exposed) of these species were collected during winter and summer seasons. Extraction media were prepared from mixtures of five solvents according t
J. Braz. Chem. Soc.. Publicado em: 2015-11
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7. Antimicrobial activity of
Anonna mucosa (Jacq.) grownin vivo and obtained byin vitro cultureBrazilian flora includes numerous species of medicinal importance that can be used to develop new drugs. Plant tissue culture offers strategies for conservation and use of these species allowing continuous production of plants and bioactive substances.
Annona mucosa has produced substances such as acetogenins and alkaloids that exhibit anBraz. J. Microbiol.. Publicado em: 2015-09
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8. CONSTITUINTES QUÍMICOS E ATIVIDADE FITOTÓXICA DAS FOLHAS DE
Annona nutans The phytochemical investigation and evaluation of the phytotoxic effect of the extract and fractions obtained from the leaves of
Annona nutans (R. E. Fr.) R. E. Fr. were performed. Phytotoxic activity was assessed on radicle and hypocotyl ofAllium cepa andLactuca sativa , where chloroform and ethyl acetatQuím. Nova. Publicado em: 2015-06
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9. In vitro cytotoxic, antifungal, trypanocidal and leishmanicidal activities of acetogenins isolated from Annona cornifolia A. St. -Hil. (Annonaceae)
Annona cornifolia A. St. -Hil. é uma pequena árvore anual perene encontrada no cerrado brasileiro; seu fruto verde é usado popularmente no tratamento de úlceras. As acetogeninas isoladas a partir das sementes de Annona cornifolia anteriormente apresentaram atividade antioxidante. Continuando as nossas investigações sobre as atividades biológicas das a
An. Acad. Bras. Ciênc.. Publicado em: 2014-06
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10. Nuevos fármacos inspirados en Annonáceas
Active secondary metabolites (ASM) play a highly significant role in the drug discovery. Natural complex chemical skeleton such as statins isolated from Aspergillus terreus, or acetogenins specific from Annonaceae family, are not able to be invented in any laboratory. The ASM isolated from Annonaces, especially acetogenins and isoquinoline alkaloids should b
Rev. Bras. Frutic.. Publicado em: 2014
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11. Assessment of toxic potential of Cerrado fruit seeds using Artemia salina bioassay
Artemia salina bioassay was used to assess toxicity of seeds and kernels of Brazilian fruits from cerrado (central high plains region) and other inner regions of the country. Water extracts of the kernels were filtered and added to Artemia cultures containing ten individuals per mL. Dose - response curves were constructed, and LD50 values were calculated. Pu
Food Sci. Technol. Publicado em: 10/05/2013
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12. Comparative analysis of the corps en cerise in several species of Laurencia (Ceramiales, Rhodophyta) from the Atlantic Ocean
Different species of Laurencia have proven to be a rich source of natural products yielding interesting bioactive halogenated secondary metabolites, such as terpenoids and acetogenins. It is shown that such compounds are accumulated in the spherical, reniform to claviform refractive inclusions called corps en cerise (CC), which are intensively osmiophilic an
Revista Brasileira de Farmacognosia. Publicado em: 24/05/2012