3 Cytogenetics
Mostrando 1-12 de 88 artigos, teses e dissertações.
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1. When karyotype is decisive for myelodysplastic syndromes diagnosis
ABSTRACT Introduction: The myelodysplastic syndromes (MDS) are a group of heterogeneous clonal hematopoietic stem cell disorders that results in peripheral blood (PB) cytopenias and bone marrow (BM) dysplasia. Dysplasia is the hallmark of the disorder, and must exceed the threshold of 10%. Conventional karyotype (KT) has a role in the classification and pro
Hematol., Transfus. Cell Ther.. Publicado em: 25/11/2019
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2. Pre-analytical parameters associated with unsuccessful karyotyping in myeloid neoplasm: a study of 421 samples
Cytogenetics is essential in myeloid neoplasms (MN) and pre-analytical variables are important for karyotyping. We assessed the relationship between pre-analytical variables (time from collection to sample processing, material type, sample cellularity, and diagnosis) and failures of karyotyping. Bone marrow (BM, n=352) and peripheral blood (PB, n=69) samples
Braz J Med Biol Res. Publicado em: 14/02/2019
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3. Comparative cytogenetics in three Melipona species (Hymenoptera: Apidae) with two divergent heterochromatic patterns
Abstract The genus Melipona is subdivided into four subgenera based on morphological characteristics, and two groups based on cytogenetic patterns. The cytogenetic information on this genus is still scarce, therefore, the goal of this study was to characterize Melipona paraensis, Melipona puncticollis, and Melipona seminigra pernigra using the following tech
Genet. Mol. Biol.. Publicado em: 29/11/2018
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4. Secondary myeloid neoplasms: bone marrow cytogenetic and histological features may be relevant to prognosis
Abstract Background: Secondary myeloid neoplasms comprise a group of diseases arising after chemotherapy, radiation, immunosuppressive therapy or from aplastic anemia. Few studies have addressed prognostic factors in these neoplasms. Method: Forty-two patients diagnosed from 1987 to 2008 with secondary myeloid neoplasms were retrospectively evaluated conce
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
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5. Identification of the MYST3-CREBBP fusion gene in infants with acute myeloid leukemia and hemophagocytosis
ABSTRACT Background: Acute myeloid leukemia presenting the MYST3-CREBBP fusion gene is a rare subgroup associated with hemophagocytosis in early infancy and monocytic differentiation. The aim of this study was to define the relevant molecular cytogenetic characteristics of a unique series of early infancy acute myeloid leukemia cases (≤24 months old), bas
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12
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6. Cytogenetics and DNA barcoding of the Round-eared bats, Tonatia (Chiroptera: Phyllostomidae): a new karyotype for Tonatia bidens
ABSTRACT There are two species of Neotropical Round-eared bats, Tonatia bidens Spix, 1823 and Tonatia saurophila Koopman & Williams, 1951, which present highly similar morphological characteristics that can lead to errors of identification. Specimens originally identified as T. bidens have recently been reclassified as T. saurophila, and the only karyotype d
Zoologia (Curitiba). Publicado em: 2015-10
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7. Cytogenetics of the Brazilian Bolitoglossa paraensis (Unterstein, 1930) salamanders (Caudata, Plethodontidae)
Plethodontid salamanders of genus Bolitoglossa constitute the largest and most diverse group of salamanders, including around 20% of living caudate species. Recent studies have indicated the occurrence of five recognized species in the Brazilian Amazon Rainforest. We present here the first cytogenetic data of a Brazilian salamander, which may prove to be a u
Genet. Mol. Biol.. Publicado em: 2014-09
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8. Molecular analysis of holoprosencephaly in South America
Holoprosencephaly (HPE) is a spectrum of brain and facial malformations primarily reflecting genetic factors, such as chromosomal abnormalities and gene mutations. Here, we present a clinical and molecular analysis of 195 probands with HPE or microforms; approximately 72% of the patients were derived from the Latin American Collaborative Study of Congenital
Genet. Mol. Biol.. Publicado em: 2014
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9. Estudos citogenéticos em peixes das famílias Heptapteridae e Pseudopimelodidae (Siluriformes)
As famílias Heptapteridae e Pseudopimelodidae, da ordem Siluriformes, são compostas por peixes de couro endêmicos da região Neotropical. A família Heptapteridae é composta por 24 gêneros e 189 espécies válidas e Pseudopimelodidae por 5 gêneros e 29 espécies descritas. Estudos citogenéticos nessas duas famílias ainda são escassos, principalmente
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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10. AvaliaÃÃo dos genes MLL, RB e TP53 em pacientes com sÃndrome mielodisplÃsica / Evaluation of genes MLL, RB and TP53 in patients with Myelodysplastic Syndromes
Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal disorders affecting the hematopoietic pluripotent cell, characterized by low cell counts in peripheral blood, dysplasia in one or more cell lines, inefficient hematopoiesis and increased risk of progression to acute myeloid leukemia. Although the disease can affect patients of other ag
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/06/2011
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11. Estudo da diversidade cariotípica em Bryconamericus ecai Silva, 2004, utilizando diferentes cromossômicos
No presente estudo foram realizadas análises citogenéticas em exemplares de Bryconamericus ecai, coletados no sistema hidrográfico da Laguna dos Patos, sendo estes os primeiros estudos para esta espécie. Todos os indivíduos analisados apresentaram 2n=52 entretanto, com diferentes fórmulas cariotípicas, resultando em 4 citótipos, sendo observada a pre
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/02/2011
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12. Estudo citogenético em duas espécies da família Callichthyidae (Callichthyinae, Siluriformes) da bacia do Rio de Contas/Bahia
The family Callichthyidae is included in the order Siluriformes, is widely distributed by the Neotropical region and comprises 194 species and eight genera, distributed in two subfamilies, Corydoradinae and Callichthyinae. Aiming to expand the cytogenetics information of the ichthyofauna of the eastern Atlantic basins, this work was done in Callichthys calli
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/02/2011