2 Adrenergic Agonists
Mostrando 13-24 de 173 artigos, teses e dissertações.
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13. Efeitos da injeção de moxonidina no controle da ingestão de sódio e regulação cardiovascular.
Deficit of water and sodium in the body is detected by receptors located in different parts of the body. These receptors or hormones signalize to specific areas in the brain that control renal responses and water and sodium intake. Among these areas are: organum vasculosum of the lamina terminalis (OVLT), subfornical organ (SFO), anteroventral third ventricl
Publicado em: 2003
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14. Sensibilidade a agonistas [beta]-adrenergicos em atrio esquerdo isolado de ratos submetidos a estresse
Following foot shock stress white adipocytes and right atria from male and right atria from female rats sacrificed at diestrous, are supersensitive to the chronotropic effect of isoprenaline. Right atria from female rats are also subsensitive to noradrenaline. In the present study, we investigated whether the inotropic response to B-adrenergic agonists was a
Publicado em: 2002
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15. Metabolic markers following beta-adrenoceptor agonist infusion in footshock-stressed rats
Stress hormones can alter metabolic functions in adipose tissue and liver, as well as the sensitivity of rat white adipocytes and rat atrial responses to ß-adrenergic agonists. In this study, we examined the effects of three daily footshock stress sessions on the plasma corticosterone, glucose, glycerol and triacylglycerol levels of fed, conscious male rats
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-09
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16. Time sequence of changes in the responsiveness of glycogen breakdown to adrenergic agonists in perfused liver of rats with insulin-induced hypoglycemia
The time-course changes of the responsiveness of glycogen breakdown to a- and ß-adrenergic agonists during insulin-induced hypoglycemia (IIH) were investigated. Blood glucose levels were decreased prior to the alteration in the hepatic responsiveness to adrenergic agonists. The activation of hepatic glucose production and glycogenolysis by phenylephrine (2
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-07
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17. Concentrações plasmaticas de corticosterona, glicose, glicerol e triacilglicerois em resposta a infusão de agonistas beta-adrenergicos em ratos submetidos a estresse por choque nas patas
Stress hormones can cause alterations in metabolic functions at the adipose tissue and liver. Moreover, repeated footshock stress induce alterations on the sensitivity to beta-adrenergic agonists in the rat white adipocytes lipolytic response. Therefore, our objective was to determine in fed and conscious male rats submitted to three daily footshock stress s
Publicado em: 2000
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18. Caracterização farmacologica do relaxamento de corpo cavernoso de coelho induzido pelo veneno de Tityus serrulatus
Títyus serrufatus ís the most dangerous scorpíon of the subfamily Tityinae in Brazíl because of the high toxicity of its venom and its widespread distribution in populous urban centers of southeastern region of the country. The most important clinical manifestations of the human envenomation by Títyus serrulatus are intense local pain and an immediate l
Publicado em: 1997
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19. Modulation of in vitro erythropoiesis. Studies with euthyroid and hypothyroid dogs.
The interactions of adrenergic agonists and thyroid hormones on the growth of erythroid colony-forming units were studied in cultures of dog marrow before and after the establishment of hypothyroidism. Erythroid colony growth in cultures form euthyroid dogs was enhanced by isoproterenol and other adrenergic agonists having beta 2-receptor specificity. With h
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20. Anticoccidial activities of 7-bromo-N-(2-imidazolidinylidene)-1H-indazol-6-amine and other alpha 2 adrenergic agonists.
Activity against the coccidial pathogen Eimeria tenella in chickens has been discovered among alpha 2 adrenergic agonists. The clonidine analog 7-bromo-N-(2-imidazolidinylidene)-1H-indazol-6-amine was active in feed at 7.5 ppm, a concentration similar to the use levels of potent commercial agents, e.g., maduramicin. Additional alpha 2 agonists were also foun
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21. Sources of calcium used during alpha 1- and alpha 2-adrenergic contractions in canine saphenous veins.
Experiments were performed to determine the role of intra- and extracellular Ca2+ during contractions of canine saphenous veins evoked with 'alpha 1'- and 'alpha 2'-adrenergic agonists. After incubation in Ca2+-free medium for 45 min, noradrenaline, clonidine and phenylephrine caused contractions, reaching a maximal amplitude rapidly and then declining to a
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22. Alpha-adrenergic modulation of the transient outward current in rabbit atrial myocytes.
1. A whole-cell voltage-clamp technique has been used to study the alpha-effects of the adrenergic agonists noradrenaline, methoxamine and phenylephrine on the action potentials and membrane currents of rabbit atrial myocytes. Experiments were carried out at 22-23 degrees C. 2. In the presence of 10(-6) M-propranolol, all three agents prolonged action potent
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23. Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding.
(Minus) [3-H] alprenolol, a potent beta-adrenergic antagonist, was used to identify binding sites in a fraction of canine cyocardium. Beta adrenergic agonists and antagonists compete for these binding sites in a manner which directly parallels their known affinity for the cardiac beta-adrenergic receptor. Thus, binding was highly stereo-specific, with the (m
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24. Alpha 1-adrenergic agonists selectively suppress voltage-dependent K+ current in rat ventricular myocytes.
The effects of alpha 1-adrenergic agonists on the waveforms of action potentials and voltage-gated ionic currents were examined in isolated adult rat ventricular myocytes by the whole-cell patch-clamp recording technique. After "puffer" applications of either of two alpha 1 agonists, phenylephrine and methoxamine, action-potential durations were increased. I