Modelos lineares generalizados mistos para dados longitudinais. / Generalized linear mixed models in longitudinal data.

AUTOR(ES)

Silvano Cesar da Costa

DATA DE PUBLICAÇÃO

2003

RESUMO

Experiments which response variables are proportions or counts are very common in several research areas, specially in the area of agriculture. The theory of generalized linear models, well difused (McCullagh &Nelder, 1989; Demetrio, 2001), is used for analyzing these experiments where the responses are independent. If the estimated variance is greater than the expected variance, the dispersion parameter is estimated including it on the parameter estimation process. When the response variable is observed over time a correlation among observations might occur and it should be taken into account in the parameter estimation. A way of dealing with this correlation is applying the methodology of generalized estimating equations (GEEs) discussed by Liang &Zeger (1986) although, in this case, the interest is on the estimates of the xed efect being the inclusion of a working correlation matrix useful to obtain more accurate estimates. Another alternative is the inclusion of a latent efect in the linear predictor to explain variabilities not considered in the model that might in uence the results. In this work the random efect and the dispersion parameter are combined and included together in the parameter estimation. Such methodology is applied to a data set obtained from an experiment realized with camu-camu to evaluate, through proportion of grafting well successful of seedling, which kind of grafting and understock are suitable to be used. Several models are fitted, since the split plot model (with independence assumption) up to the model where the dispersion parameter and the random efect are considered together. There is evidence that the model including the random efect and the dispersion parameter together, produce better estimates of the parameters. Another longitudinal data set used here comes from an experiment realized with the MON810 transgenic corn where the response variable is the number of caterpillars (Spodoptera frugiperda). In this case, due to the excessive number of zeros obtained, the zero in ated Poisson regression model (ZIP) is used in addition to the standard Poisson model, where observations are considered independent, and the zero in ated Poisson regression model with random efect. The results show that the random efect included in the linear predictor was not significant and, therefore, the adopted model is the zero in ated Poisson regression model. The results were obtained using the procedures NLMIXED, GENMOD and GPLOT available on SAS - Statistical Analysis System, version 8.2.

ASSUNTO(S)

análise de dados longitudinais poisson distribution em algorithm modelos lineares generalizados generalized linear models sas (programa de computador) generalized linear mixed models distribuição binomial distribuição de poisson binomial distribution

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