Antivenom
Mostrando 1-12 de 131 artigos, teses e dissertações.
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1. Como operacionalizar o atendimento de pacientes indígenas vítimas de acidentes ofídicos nas comunidades indígenas remotas da Amazônia Brasileira?
Os antivenenos são o único tratamento eficaz contra os efeitos de picadas de cobras venenosas e sua aplicação imediata é crucial para evitar complicações, sequelas e morte
. Desse modo, enquanto não ocorre a descentralização do tratamento antiveneno para unidades básicas de saúde indígena mais próximos das populacionais indígenas, os
Núcleo de Telessaúde Amazonas. Publicado em: 12/06/2023
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2. Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of their ability to inhibit some in vitro (coagulant, proteolytic and hemolytic) and in vivo (hemorrhagic, edematogenic and lethality) toxic activities of Bothrops jararaca and Bothrops jararacussu venoms. Compounds have been synthesized from the coupling of intermedi
Journal of the Brazilian Chemical Society. Publicado em: 2022
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3. The WHO strategy for prevention and control of snakebite envenoming: a sub-Saharan Africa plan
Abstract Snakebite is a critical public health issue in tropical countries, particularly in Africa, where 20% of snakebites globally occur. In 2017, the WHO added snakebite envenoming to the category A of neglected tropical diseases. In 2019, thanks to broad institutional and international NGO support, including strong mobilization of African experts and gov
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/12/2019
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4. Epidemiological and clinical aspects of snakebites in the upper Juruá River region, western Brazilian Amazonia
RESUMO Este estudo aborda os aspectos clínicos e epidemiológicos dos envenenamentos ofídicos tratados em um hospital em Cruzeiro do Sul, Acre, resultantes de acidentes que ocorreram na região do Alto Juruá, no oeste da Amazônia brasileira. A identidade específica das serpentes que causaram os envenenamentos foi inferida (a) pelos sinais e sintomas apr
Acta Amaz.. Publicado em: 25/11/2019
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5. Hemorrhagic stroke following viper bites and delayed antivenom administration: three case reports from the Western Brazilian Amazon
Abstract Snakebites were included by the World Health Organization in their list of neglected diseases. In Latin America, most snakebites are caused by species of the Viperidae family, notably by the genus Bothrops. Bothrops atrox accounts for 90% of the cases of envenoming in the Brazilian Amazon. In this report, we present a series of three cases of snakeb
Rev. Soc. Bras. Med. Trop.. Publicado em: 18/07/2019
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6. Envenomation by an opisthoglyphous snake, Erythrolamprus aesculapii (Dipsadidae), in southeastern Brazil
Abstract Snakebites by aglyphous or opisthoglyphous snakes are common in Brazil. We report a case of snakebite by the opisthoglyphous Erythrolamprus aesculapii. The victim presented with pain, edema, and bleeding at the bite site, along with erythema, similar to a Bothrops envenomation. In this type of snakebite, if the snake is not brought to the hospital,
Rev. Soc. Bras. Med. Trop.. Publicado em: 30/05/2019
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7. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities
Abstract Background: Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of Morocco and Saudi Arabia. The envenomation is characterized by local and systemic reactions including pain, blistering, edema and tissue damage, besides hemostatic and cardiovascular disturbances, which can cause death or permanent disabilities in its victims
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/01/2019
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8. Clinical and laboratory features distinguishing between Deinagkistrodon acutus and Daboia siamensis envenomation
Abstract Background: There are 6 species of venomous snakes in Taiwan. Two of them, Deinagkistrodon acutus (D. acutus) and Daboia siamensis (D. siamensis), can cause significant coagulopathy. However, a significant proportion of patients with snakebites cannot identify the correct snake species after envenomation, which hampers the application of antivenom.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/01/2019
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9. Antivenomic approach of different Crotalus durissus collilineatus venoms
Abstract Background: Our group has previously performed a proteomic study verifying that individual variations can occur among Crotalus durissus collilineatus venoms. These variations may lead to differences in venom toxicity and may result in lack of neutralization of some components by antivenom. In this way, this study aimed to evaluate the Brazilian ant
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
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10. Sequence analysis of the cDNA encoding for SpCTx: a lethal factor from scorpionfish venom ( Scorpaena plumieri )
Abstract Background: Lethal factors are multifunctional oligomeric proteins found in the venomous apparatus of Scorpaeniformes fish. These toxins elicit not only an array of biological responses in vitro but also cardiovascular disorders and strong hemolytic, nociceptive and edematogenic activities in vivo. This work describes the cloning and molecular iden
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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11. Delayed double reading of whole blood clotting test (WBCT) results at 20 and 30 minutes enhances diagnosis and treatment of viper evenomation
Abstract Background The whole blood clotting test (WBCT) is a simple test of coagulation that is often used in the assessment, diagnosis, and therapeutic monitoring of snakebite patients in sub-Saharan Africa. WBCT requires only a clean glass tube and several milliliters of venous blood and is ideal for use in poorly equipped health centers throughout the r
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/06/2018
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12. True or false coral snake: is it worth the risk? A Micrurus corallinus case report
Abstract Background Bites provoked by the genus Micrurus represent less than 1% of snakebite cases notified in Brazil, a tiny fraction compared with other genus such as Bothrops and Crotalus, which together represent almost 80% of accidents. In addition to their less aggressive behavior, habits and morphology of coral snakes are determinant factors for such
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/05/2018