Y Irradiation
Mostrando 37-48 de 116 artigos, teses e dissertações.
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37. Therapeutic outcome of patients suffering from malignant melanomas of the conjunctiva.
Eighty-one cases of conjunctival melanoma treated between 1960 and 1988 were studied to determine factors that might affect outcome in patients with such lesions. The therapeutic procedures performed were local excision (16), local excision followed by brachytherapy with Sr-90/Y-90 (32), local excision followed by cryotherapy with liquid nitrogen (16), brach
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38. Suppression of unprimed T and B cells in antibody responses by irradiation-resistant and plastic-adherent suppressor cells in Toxoplasma gondii-infected mice.
In the acute phase of Toxoplasma infection, the function of both helper T and B cells was suppressed in primary antibody responses to dinitrophenol (DNP)-conjugated protein antigens. During the course of infection, the suppressive effect on T cells seems to continue longer than that on B cells, since suppression in responses to sheep erythrocytes, a T-depend
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39. Collagen breakdown during acute lung injury.
Injury to the capillary endothelium and to alveolar epithelial cells of the lung may result in damage to the underlying collagen of the extracellular matrix. To examine this possibility, whole body irradiation, bleomycin injections, and exposure to hyperoxia were used to induce various types of lung damage in mice. The morphology of the lung and the cellular
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40. Histological study of effects of colloidal 90 yttrium on knee joint tissues of rabbits.
The administration of 0-2-0-4 mCi 90 yttrium (90Y) into a normal rabbit knee joint fails to induce medical synovectomy and results in the proliferation of the synovialis. The synovial mesothelium shows early radiation damage but subsequently follows a restitution of the whole. Later (within 4 to 16 weeks) an extensive fibrosis of the stratum synovialis devel
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41. Properties of the nonlethal recombinational repair x and y mutants of bacteriophage T4. II. DNA synthesis.
The bacteriophage T4 recombination-deficient mutants x and y exhibited decreased rates of DNA synthesis as compared to wild-type T4. Mutant-induced DNA synthesis was more sensitive to mitomycin C than was wild-type synthesis. However, DNA synthesis in mutant- and wild-type-infected cells exhibited the same sensitivity to UV light and X-irradiation. When high
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42. Multicopy derivative of pock-forming plasmid pSA1 in Streptomyces azureus.
Streptomyces azureus carried one copy or less of plasmid pSA1, which elicited pocks at 0.1 to 1.0%. Strain PK100 was isolated from the wild-type strain after UV irradiation. PK100 carried approximately 20 to 30 copies of pSA1.1, a derivative of pSA1. Plasmid pSA1.1 elicited pocks at 100% and inhibited spore and thiostrepton production.
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43. Inhibition of the development of radiation-induced leukemia in mice by reduction of food intake.
We have reported previously that the incidence of tumors induced in Sprague-Dawley rats by total-body gamma-ray irradiation can be considerably reduced by restriction of food intake [Gross, L. & Dreyfuss, Y. (1984) Proc. Natl. Acad. Sci. USA 81, 7596-7598]. In experiments reported here we investigated the influence of reduced food intake on the development o
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44. Chromosomal Mapping by Means of Mutational Induction in Synchronous Populations of Streptococcus faecalis
Stonehill, E. H. (Sloan-Kettering Institute for Cancer Research, New York, N.Y. and Dorris J. Hutchison. Chromosomal mapping by means of mutational induction in synchronous populations of Streptococcus faecalis. J. Bacteriol. 92:136–143. 1966.—A new method for mapping genetic loci on the bacterial chromosome, based on the linear progression of the deoxyr
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45. Isolation of Deficiencies in the Arabidopsis Genome by γ-Irradiation of Pollen
Chromosomal deficiencies are a useful genetic tool in fine-scale genetic mapping and the integration of physical and visible marker genetic maps. Viable overlapping deficiencies may permit gene cloning by subtractive procedures and provide a means of analyzing the functional importance of different chromosomal regions. A method is described for isolation of
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46. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.
Normal p53 function is required for optimal arrest of cells in the G1 phase of the cell cycle following certain types of DNA damage. Loss of this cell cycle checkpoint may contribute to tumor development by increasing the number of genetic abnormalities in daughter cells following DNA damage. The MDM2 protein is an endogenous gene product that binds to the p
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47. Characterization of dinY, a new Escherichia coli DNA repair gene whose products are damage inducible even in a lexA(Def) background.
Bacteriophage Mu dX(Ap lac) was used to isolate a mutation in an Escherichia coli lexA(Def) strain representing a previously undescribed gene (dinY) which does not seem to be under the direct control of LexA. The insertion created a dinY::lacZ fusion in which beta-galactosidase expression required a DNA-damaging treatment (UV irradiation or mitomycin) and ac
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48. Specificity, Induction, and Absorption of Pesticin1
Irradiation of pesticinogenic (Pst+) cells of Yersinia pestis with ultraviolet light resulted in a five- to eightfold increase in titer of intracellular pesticin. Extracellular activity in irradiated or control cultures never approached that found within the bacteria. Upon chromatography of crude extracts of Pst+ cells on columns of diethylaminoethyl-cellulo