Water Maze
Mostrando 13-24 de 140 artigos, teses e dissertações.
-
13. Behavioral alterations induced by repeated saxitoxin exposure in drinking water
Abstract Background Blooms of the saxitoxin-producing cyanobacterium Cylindrospermopsis raciborskii have been contaminating drinking water reservoirs in Brazil for many years. Although acute effects of saxitoxin intoxication are well known, chronic deleterious outcomes caused by repeated saxitoxin exposure still require further investigation. The aim of th
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 14/06/2016
-
14. Antioxidant Activity of Oral Administration of Rosmarinus Officinalis Leaves Extract on Rat's Hippocampus which Exposed to 6-Hydroxydopamine
Carnosic acid, a diterpene of Rosemarinus officinalis leaves extract (RE), has potent antioxidant activity in vitro. The dopaminergic connection of substantia nigra pars compacta to the hippocampus might be affected by oxidative stress which caused cognitive impairment observed in the early phase of Parkinson's disease (PD). Adult male Wistar rats were lesio
Braz. arch. biol. technol.. Publicado em: 29/04/2016
-
15. Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning
We evaluated the effect of puerarin on spatial learning and memory ability of mice with chronic alcohol poisoning. A total of 30 male C57BL/6 mice were randomly divided into model, puerarin, and control groups (n=10 each). The model group received 60% (v/v) ethanol by intragastric administration followed by intraperitoneal injection of normal saline 30 mi
Braz J Med Biol Res. Publicado em: 27/03/2015
-
16. Possible roles of COX-1 in learning and memory impairment induced by traumatic brain injury in mice
People who suffer from traumatic brain injury (TBI) often experience cognitive deficits in spatial reference and working memory. The possible roles of cyclooxygenase-1 (COX-1) in learning and memory impairment in mice with TBI are far from well known. Adult mice subjected to TBI were treated with the COX-1 selective inhibitor SC560. Performance in the open f
Braz J Med Biol Res. Publicado em: 16/09/2014
-
17. Phytoestrogen -zearalanol ameliorates memory impairment and neuronal DNA oxidation in ovariectomized mice
OBJECTIVE: The aim of this study was to evaluate the effect of a novel phytoestrogen, α-Zearalanol, on Alzheimer's disease-related memory impairment and neuronal oxidation in ovariectomized mice. METHODS: Female C57/BL6 mice were ovariectomized or received sham operations and treatment with equivalent doses of 17β-estradiol or α-Zearalanol for 8 weeks.
Clinics. Publicado em: 2013-09
-
18. Learning and survival memory undergoing a permanent bilateral carotid ligation in rats
PURPOSE: To evaluate the effect of cerebral hypoxia-ischemia on memory and learning survival of rats submitted to permanent bilateral carotid ligation (PBCL). METHODS: Twenty-four survivors of PBCL were evaluated after 30 days with regard to memory and learning using a water survival maze. Twenty-three healthy rats were used as control group. The results wer
Acta Cir. Bras.. Publicado em: 2013-02
-
19. Análise neurofarmacológica e neuroquímica da expressão de memórias espaciais
Memories are not stored in its final form immediately after the acquisition. They undergo a long stabilization process known as consolidation. Consolidated memories can become labile again after the retrieval and susceptible to the action of amnesic agents. Thus, to persist must go through the re-stabilization process called reconsolidation. Several evidence
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/05/2012
-
20. Maternal separation during breastfeeding induces changes in the number of cells immunolabeled to GFAP
The mother-child relationship is fundamental to the establishment and maintenance of synaptic networks and physiological and emotional development. Animal models including maternal separation have been used to study changes at behavioral and neurobiochemical levels. Due to the relevance of glial cells during development, our aim was to determine if short per
Psychol. Neurosci.. Publicado em: 2012-12
-
21. Efeitos da administração de ácido fólico sobre parâmetros comportamentais, bioquímicos e morfológicos em ratos submetidos à hipóxia-isquemia encefálica neonatal
Perinatal hypoxic-ischemic (HI) is a significant cause of mortality and morbidity in infants and young children. Folic acid is a water soluble vitamin that can be obtained through diet and has been related to the antioxidant effect, protecting ischemic events and Alzheimer s disease. The aim of this study was to investigate the role of the folic acid treatme
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
-
22. Impairment of spatial performance by continuous intensive noise: a behavioral view
A wide range of animal and human investigations have tested the neurobiological and immunological aspects of noise. Few studies, however, have explored the behavioral characteristics of noise on neuromotor movements. To examine this correlation, we tested the effects of continuous intensive noise on retention and contextual transfer in a spatial memory task
Psychology & Neuroscience. Publicado em: 2011-12
-
23. Anxiolytic-like and sedative effects of Hydrocotyle umbellata L., Araliaceae, extract in mice
The plant Hydrocotyle umbellata L., Araliaceae (water pennywort), is widely used in Brazilian folk medicine to reduce anxiety. This work investigates the anxiolytic-like effects of the ethanol extract from H. umbellata subterraneous parts as well as the extract's other putative central nervous system effects that could justify its common use. Oral dosing of
Revista Brasileira de Farmacognosia. Publicado em: 25/02/2011
-
24. The modified 2VO ischemia protocol causes cognitive impairment similar to that induced by the standard method, but with a better survival rate
Permanent bilateral occlusion of the common carotid arteries (2VO) in the rat has been established as a valid experimental model to investigate the effects of chronic cerebral hypoperfusion on cognitive function and neurodegenerative processes. Our aim was to compare the cognitive and morphological outcomes following the standard 2VO procedure, in which ther
Publicado em: 2011