Voluntary Wheel Running
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Voluntary wheel running: patterns and physiological effects in mice
Exercise can prevent and improve the pathophysiology of diseases and promote healthy aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise may lead to the development of new strategies to enhance quality of life and to counteract chronic diseases. Voluntary wheel running is an interesting model to study the effects of exe
Braz J Med Biol Res. Publicado em: 10/12/2018
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2. Voluntary exercise prior to traumatic brain injury alters miRNA expression in the injured mouse cerebral cortex
MicroRNAs (miRNAs) may be important mediators of the profound molecular and cellular changes that occur after traumatic brain injury (TBI). However, the changes and possible roles of miRNAs induced by voluntary exercise prior to TBI are still not known. In this report, the microarray method was used to demonstrate alterations in miRNA expression levels in th
Braz J Med Biol Res. Publicado em: 06/03/2015
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3. Expressão do Coativador-1 do Peroxisome Proliferator-Activated Receptor- (PGC-1) em fígado e músculos esqueléticos soleus e plantaris de ratos machos Wistar submetidos ao exercício físico voluntário crônico / Peroxisome Proliferator-Activated Receptor- - Coactivator-1 ( PGC-1 ) expression in the liver and skeletal muscles soleus and plantaris of male Wistar rats subjected to chronic voluntary exercise
INTRODUCTION: The Peroxisome Proliferator-Activated Receptor- - Coactivator 1 ( PGC-1 e ) is a protein responsible for the connection between environmental stimuli and cell metabolic response. Its presence is important in fat tissue, hepatic and skeletal muscle and in animals on brown fat tissue. Interact with nuclear receptors modulating the mitochondrial b
Publicado em: 2009
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4. Physical activity and neuroprotection in adult mice after pilocarpine induced status epilepticus / Atividade fisica e neuroproteção em camundongos adultos após indução de status epilepticus por pilocarpina
Pilocarpine-induced epilepsy in mice is an experimental model of the Temporal Lobe Epilepsy (TLE). Status epilepticus determined by pilocarpine adminstration leads to behavioral and electroencephalographic changes and neuronal damage similar to those observed in TLE. Recently, it has been shown that physical activity exerts neuroprotective effects, such as i
Publicado em: 2005
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5. Differential effects of treadmill running and wheel running on spatial or aversive learning and memory: roles of amygdalar brain-derived neurotrophic factor and synaptotagmin I
Chronic exercise has been reported to improve cognitive function. However, whether and how different types of exercise affect various learning and memory tasks remain uncertain. To address this issue, male BALB/c mice were trained for 4 weeks under two different exercise protocols: moderate treadmill running or voluntary wheel running. After exercise trainin
Blackwell Science Inc.
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6. Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase
Habitual aerobic exercise is associated with enhanced endothelium-dependent dilatation (EDD) in older humans, possibly by increasing nitric oxide bioavailability and reducing oxidative stress. However, the mechanisms involved are incompletely understood. EDD was measured in young (6–8 months) and old (29–32 months) cage control and voluntary wheel runnin
Blackwell Science Inc.
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7. Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats
Using the hyperphagic, obese, Otsuka Long–Evans Tokushima Fatty (OLETF) rat, we sought to determine if progression to type 2 diabetes alters visceral white adipose tissue (WAT) mitochondrial content and if these changes are modified through prevention of type 2 diabetes with daily exercise. At 4 weeks of age, OLETF rats began voluntary wheel running (OLETF
Blackwell Science Inc.
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8. Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis
We used recombinant adeno-associated virus (rAAV)-mediated gene delivery to overexpress a mutant of rat leptin yielding a protein that acts as a neutral leptin receptor antagonist. The long-term consequences of this overexpression on body weight homeostasis and physical activity, as assessed by voluntary wheel running (WR), were determined in F344 × Brown N
American Physiological Society.
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9. Muscle injury, cross-sectional area and fibre type distribution in mouse soleus after intermittent wheel-running.
1. It was previously noticed that mouse soleus, but not extensor digitorum longus (EDL) muscles, suffer fibre damage at the onset of voluntary wheel-running without further injuries thereafter. 2. In CBA/J mice trained continuously for 5 months and rested for periods of 1, 2, 3, 4 and 5 weeks acute muscle damage was found in soleus 7 days after the resumptio
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10. Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats
Regular physical activity improves glucose tolerance and decreases adiposity. Our aim was to investigate the effects of exercise training on subcutaneous (inguinal) and visceral (parametrial) adipose tissue in rats that were fed a chow diet (13% fat) or made insulin resistant by a high-fat diet (60% fat). Sprague-Dawley rats performed 4 wk of voluntary wheel
American Physiological Society.