Voltage Surge
Mostrando 13-17 de 17 artigos, teses e dissertações.
-
13. Large conductance Ca(2+)-activated K+ channels are involved in both spike shaping and firing regulation in Helix neurones.
1. The role of BK-type calcium-dependent K+ channels (K+Ca) in cell firing regulation was evaluated by performing whole-cell voltage clamp and patch clamp experiments on the U cell neurones in the snail Helix pomatia. These cells were selected because most of the repolarizing K+ current flowed through K+Ca channels. 2. U cells generated overshooting Ca(2+)-d
-
14. Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling
Oxidant-liberated intracellular Zn2+ regulates neuronal apoptosis via an exocytotic membrane insertion of Kv2.1-encoded ion channels, resulting in an enhancement of voltage-gated K+ currents and a loss of intracellular K+ that is necessary for caspase-mediated proteolysis. In the present study we show that an N-terminal tyrosine of Kv2.1 (Y124), which is a k
Blackwell Science Inc.
-
15. Intracellular injection of Ca2+ chelators blocks induction of long-term depression in rat visual cortex.
In a variety of brain structures repetitive activation of synaptic connections can lead to long-term potentiation (LTP) or long-term depression (LTD) of synaptic transmission, and these modifications are held responsible for memory formation. Here we examine the role of postsynaptic Ca2+ concentration in the induction of LTD in the neocortex. In layer III ce
-
16. Sodium and potassium conductances in somatic membranes of rat Purkinje cells from organotypic cerebellar cultures.
1. The somatic voltage-gated conductances of Purkinje cells in organotypic cultures (Gähwiler, 1981) were studied using the outside-out patch recording configuration of the patch-clamp technique (Hamill, Marty, Neher, Sakmann & Sigworth, 1981). 2. When activated by step depolarizations, the tetrodotoxin-sensitive voltage-dependent Na+ current presented two
-
17. The calcium current of mouse egg measured in physiological calcium and temperature conditions.
1. Voltage-clamp experiments have been performed on ovulated mouse eggs using the whole-cell recording technique. 2. Whole-cell recording offers improved signal-to-noise ratio and excellent stability over time. This allowed the study of the Ca2+ current of these eggs under physiological conditions (i.e. 1.7 mM-external Ca2+ and 37 degrees C). 3. In these con