Viral Pathogenesis
Mostrando 13-24 de 923 artigos, teses e dissertações.
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13. Porcine circovirus 2 (PCV2) increases the expression of endothelial adhesion/junction molecules
Abstract Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus disease, a complex multisystem syndrome in domestic pigs. Despite the significant economic losses caused by porcine circovirus disease, the mechanisms of pathogenesis underlying the clinical findings remain largely unclear. As various reports have highlighted the p
Braz. J. Microbiol.. Publicado em: 2016-12
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14. Epidemiology of hepatitis B virus in the cities of the northern region of Espírito Santo, Brazil
ABSTRACT The World Health Organization (WHO) estimates that approximately 2 billion people worldwide have already had contact with hepatitis B virus (HBV) and 373 million have become chronic carriers. Hepatitis B is a major cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma, leading to a large number of deaths annually. Both viral factors and
An. Acad. Bras. Ciênc.. Publicado em: 04/08/2016
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15. Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?
Abstract: The Zika virus epidemic that started in Brazil in 2014 has spread to >30 countries and territories in Latin America, leading to a rapid rise in the incidence of microcephalic newborns and adults with neurological complications. At the beginning of the outbreak, little was known about Zika virus morphology, genome structure, modes of transmission, a
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-06
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16. Evaluation and optimization of SYBR Green real-time reverse transcription polymerase chain reaction as a tool for diagnosis of the Flavivirus genus in Brazil
Abstract: INTRODUCTION: The genus Flavivirus includes several pathogenic species that cause severe illness in humans. Therefore, a rapid and accurate molecular method for diagnosis and surveillance of these viruses would be of great importance. Here, we evaluate and optimize a quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) m
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-06
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17. The role of microRNAs in enteroviral infections
ABSTRACTThe genus Enterovirus, a member of thePicornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRN
Braz J Infect Dis. Publicado em: 2015-10
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18. Molecular characterisation of the NSP4 gene of group A human rotavirus G2P[4] strains circulating in São Paulo, Brazil, from 1994 and 2006 to 2010
Group A human rotaviruses (HuRVA) are causative agents of acute gastroenteritis. Six viral structural proteins (VPs) and six nonstructural proteins (NSPs) are produced in RV-infected cells. NSP4 is a diarrhoea-inducing viral enterotoxin and NSP4 gene analysis revealed at least 15 (E1-E15) genotypes. This study analysed the NSP4 genetic diversity of HuRVA G2P
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-09
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19. Japanese encephalitis: a review of the Indian perspective
Japanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age. The JEV has shown a tendency to extend to other geographic regions. Case fatality averages 30% and a high percentage of the survivors are left with perman
Braz J Infect Dis. Publicado em: 2012-12
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20. CARACTERIZAÇÃO MOLECULAR DE LENTIVÍRUS DE PEQUENOS RUMINANTES ISOLADOS NO BRASIL / MOLECULAR CHARACTERIZATION OF Small ruminant lentiviruses ISOLATED IN BRAZIL
CAEV and MVV have been considered genetically distinct but antigenically related as pathogens of goats and sheep, respectively. Moreover, it was demonstrated that these viruses are constantly and easily breaking the barrier between sheep and goats, sheep being infected with CAEV and MVV infecting goats. Like all lentiviruses, the genome of CAEV has a high mu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/12/2011
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21. Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-α and IFN-α profiles
Flaviviruses cause severe acute febrile and haemorrhagic infections, including dengue and yellow fever and the pathogenesis of these infections is caused by an exacerbated immune response. Dendritic cells (DCs) are targets for dengue virus (DENV) and yellow fever virus (YF) replication and are the first cell population to interact with these viruses during a
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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22. Europe: history, current situation and control measures for infectious bronchitis
The emergence and nature of different strains of infectious bronchitis virus (IBV) in Europe are described. Infectious bronchitis (IB) is the most important endemic viral respiratory disease where highly pathogenic Newcastle disease and avian influenza are not present. IB was first described in the UK in 1948 and identified as Massachusetts type. In the 1970
Revista Brasileira de Ciência Avícola. Publicado em: 2010-06
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23. Implications of infectious diseases and the adrenal hypothesis for the etiology of childhood acute lymphoblastic leukemia
Acute leukemia is the most frequent cancer in children. Recently, a new hypothesis was proposed for the pathogenesis of childhood acute lymphoblastic leukemia (ALL). The so-called "adrenal hypothesis" emphasized the role of endogenous cortisol in the etiology of B-cell precursor ALL. The incidence peak of ALL in children between 3 to 5 years of age has been
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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24. INFECÇÃO EXPERIMENTAL DE COELHOS E CAMUNDONGOS COM O VÍRUS DO ECTIMA CONTAGIOSO / EXPERIMENTAL INFECTION OF RABBITS AND MICE WITH CONTAGIOUS ECTHYMA VIRUS
Contagious ecthyma (orf) is a cutaneous disease that affects sheep and goats, and may be occasionally transmitted to humans. The disease is caused by orf virus (ORFV). ORFV infection produces croustous and proliferative lesions, usually on the nostrils and labial commissures of lambs, and also in the udder, teat skin and coronary bands of adults animals. The
Publicado em: 2010