Viral Genetic Determinants
Mostrando 1-12 de 102 artigos, teses e dissertações.
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1. Genetic and biological characterisation of Zika virus isolates from different Brazilian regions
BACKGROUND Zika virus (ZIKV) infections reported in recent epidemics have been linked to clinical complications that had never been associated with ZIKV before. Adaptive mutations could have contributed to the successful emergence of ZIKV as a global health threat to a nonimmune population. However, the causal relationships between the ZIKV genetic determi
Mem. Inst. Oswaldo Cruz. Publicado em: 19/08/2019
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2. Determinantes virais envolvidos na adaptabilidade diferencial de dois begomovírus em tomateiro e Nicotiana benthamiana / Viral determinants involves in the differential adaptation of two begomovirus in tomato and Nicotiana benthamiana
Begomoviruses (family Geminiviridae) have a genome composed of a one or two components of circular, single-stranded DNA and infect dicotyledoneous plants. Symptoms induced by the begomovirus Tomato yellow spot virus (ToYSV) in tomato and Nicotiana benthamiana are more severe and appear earlier compared to those induced by Tomato rugose mosaic virus (ToRMV).
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/12/2011
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3. HLA-Bw4-B*57 and Cw*18 alleles are associated with plasma viral load modulation in HIV-1 infected individuals in Salvador, Brazil
Host genetic factors play an important role in mediating resistance to HIV-1 infection and may modify the course of infection. HLA-B alleles (Bw4 epitope; B*27 and B*57) as well as killer cell immunoglobulin-like receptors have been associated with slow progression of HIV-1 infection. OBJECTIVE: To evaluate the association between serological epitopes HLA-Bw
Brazilian Journal of Infectious Diseases. Publicado em: 2010-10
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4. Laboratorial atopy markers in children with human immunodeficiency virus
Changes in immune system functions are one of the most important consequences of human immunodeficiency virus (HIV) infection. Studies have reported a higher prevalence of disease mediated by immunological hypersensitivity mechanisms in HIV-positive patients. This study aims to observe how immunological changes in HIV-infected children interfere in atopy det
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-05
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5. Analysis of the viral genetic determinants of symptom induction by a begomovirus in tomato and Nicotiana benthamiana / Análise de determinantes virais envolvidos na indução diferencial de sintomas por begomovírus em tomateiro e Nicotiana benthamiana
Os vírus pertencentes à família Geminiviridae são caracterizados pelo genoma composto por DNA circular de fita simples, encapsidado em uma partícula icosaédrica geminada. As espécies do gênero Begomovirus possuem grande importância econômica. No Brasil, o tomateiro é infectado por um complexo com pelo menos oito espécies de begomovírus. Dentre e
Publicado em: 2006
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6. Multiple viral core proteins are determinants of reovirus-induced acute myocarditis.
Previously, we showed that the M1 gene (encoding a viral core protein, mu 2, whose function is unknown) was associated with the efficiently myocarditic phenotype of a reovirus variant, 8B. Here, we have extended our genetic analysis of 8B and conducted genetic analyses of two other reovirus strains (T1L [serotype 1 strain Lang] and Abney). Our results demons
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7. Primate retroviruses: envelope glycoproteins of endogenous type C and type D viruses possess common interspecies antigenic determinants.
The major 70,000- to 80,000-molecular-weight envelope glycoproteins of the squirrel monkey retrovirus, Mason-Pfizer monkey virus, and M7 baboon virus and the related endogenous feline virus, RD114, were isolated and immunologically characterized. Immunoprecipitation and competition immunoassay analysis revealed these viral envelope glycoproteins to possess s
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8. Tissue Specificity of Geminivirus Infection Is Genetically Determined
The types of cells and tissues infected by a virus define its tissue tropism. Determinants of tissue tropism in animal-infecting viruses have been extensively investigated, but little is known about plant viruses in this regard. Some geminiviruses in the genus Begomovirus exhibit phloem limitation and are restricted to cells of the vascular system, whereas o
American Society of Plant Physiologists.
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9. RNA recombination of coronaviruses: localization of neutralizing epitopes and neuropathogenic determinants on the carboxyl terminus of peplomers.
Murine coronaviruses undergo RNA recombination at a very high frequency. We have obtained a series of recombinant viruses using neutralizing monoclonal antibodies in conjunction with temperature-sensitive markers. All of the recombinants obtained have a crossover within gene C, which encodes the peplomer protein of the virus. The genetic structure of these r
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10. Viral genetic determinants for thrips transmission of Tomato spotted wilt virus
Tomato spotted wilt virus (TSWV) is transmitted exclusively by thrips in nature. A reassortment-based viral genetic system was used to map transmissibility by thrips to the medium (M) RNA of TSWV. To locate determinants of thrips transmission in the M RNA, 30 single-lesion isolates (SLIs) were generated from a single TSWV isolate that was inefficiently trans
National Academy of Sciences.
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11. Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity.
Human immunodeficiency virus 2 (HIV-2) ISY and the newly derived HIV-2KR are infectious molecular clones that yield viruses differing markedly in their abilities to infect and/or induce syncytia in various T- and monocytoid-cell lines. Chimeric viruses were constructed from these two viral genomes to localize the genetic determinants of some of these propert
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12. Vector Infection Determinants of Venezuelan Equine Encephalitis Virus Reside within the E2 Envelope Glycoprotein
Epizootic subtype IAB and IC Venezuelan equine encephalitis viruses (VEEV) readily infect the epizootic mosquito vector Aedes taeniorhynchus. The inability of enzootic subtype IE viruses to infect this mosquito species provides a model system for the identification of natural viral determinants of vector infectivity. To map mosquito infection determinants, r
American Society for Microbiology.