Vincristine
Mostrando 13-24 de 138 artigos, teses e dissertações.
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13. Case for diagnosis
We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present
An. Bras. Dermatol.. Publicado em: 2014-07
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14. Outcomes of autologous transplantation for multiple myeloma according to different induction regimens
Background: Induction therapy followed by high-dose chemotherapy and autologous transplantation is the standard treatment for suitable patients with multiple myeloma. Objective: The aim of this study was to assess whether induction therapy with thalidomidecontaining regimens was associated with improved results compared to vincristine, doxorubicin, and
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-01
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15. Identification of microRNAs and mRNAs associated with multidrug resistance of human laryngeal cancer Hep-2 cells
Multidrug resistance (MDR) poses a serious impediment to the success of chemotherapy for laryngeal cancer. To identify microRNAs and mRNAs associated with MDR of human laryngeal cancer Hep-2 cells, we developed a multidrug-resistant human laryngeal cancer subline, designated Hep-2/v, by exposing Hep-2 cells to stepwise increasing concentrations of vincristin
Braz J Med Biol Res. Publicado em: 12/06/2013
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16. Effect of curcumin on human colon cancer multidrug resistance in vitro and in vivo
OBJECTIVE: To determine whether curcumin reverses the multidrug resistance of human colon cancer cells in vitro and in vivo. METHODS: In a vincristine-resistant cell line of human colon cancer, the cell viability of curcumin-treated cells was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Rhodamine123 efflux was e
Clinics. Publicado em: 2013-05
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17. Remodelamento do tumor venéreo transmissível / Remodeling of the canine transmissible venereal tumor during treatment with vincristine sulfate
O tumor venéreo transmissível canino (TVTC) é transmitido por meio da transplantação de células neoplásicas. O sulfato de vincristina é o agente quimioterápico mais utilizado no tratamento do TVTC. O objetivo deste estudo foi comparar as alterações morfológicas antes da quimioterapia e após uma semana da aplicação de uma injeção intravenosa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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18. Linfoma esofágico primário
We describe the case of a 54 year old woman seen with an esophageal mass diagnosed as a primary esophageal lymphoma. The main symptom was dysphagia of seven months duration. The treatment consisted in resection of the tumor, and reconstruction of the defect with a reversed pleural flap, followed by a chemotherapy regimen that consisted of five drugs, cycloph
Revista do Colégio Brasileiro de Cirurgiões. Publicado em: 2012-06
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19. Estudo do metabolismo de microRNAs na resistência de células leucêmicas / Study of microRNA metabolism in leukemik cells resistance
Drug resistance is one of the main obstacles in cancer therapy. Frequently, the treatment of chronic myelogenous leukemia (CML) becomes inefficient due to the emergence of a resistant population of cancer cells. Therefore, comparative studies of resistant and non-resistant CML cell lines is extremely important to the understanding of molecular mechanisms inv
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2011
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20. Intellectual aspects of cognitive performance in children after treatment for medulloblastoma and astrocytoma
The present study investigated the relationship between posterior fossa tumors (astrocytoma and medulloblastoma) and their respective treatments and cognitive performance in Brazilian children by measuring Intelligence Quotient (IQ). Twenty children were enrolled in the study, of whom 13 were diagnosed with astrocytoma (average age at evaluation, 10.2 years;
Psychology & Neuroscience. Publicado em: 2010-12
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21. Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
This review demonstrates the importance of plants as sources of molecules used in anticancer therapies. The approach is performed by relating the active molecules to their origins, details, mechanisms of action, structure-activity relationship and chemical characteristics of chemotherapeutical medicines. It was also described the development of anticancer ag
Química Nova. Publicado em: 2010
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22. Doença de Hodgkin: análise do protocolo DH-II-90 / Hodgkins disease: the protocol DH-II-90
The treatment of Hodgkin´s disease (HD) has been increasingly successful lately. Since today cure rates are about 85%, the challenge of new protocols for treatment of HD is to decrease its aggressiveness and consequent acute and late toxicity, without impairing results. The protocol DH-II-90 was designed to treat children and adolescents with HD. It consist
Publicado em: 2010
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23. Sulfato de vincristina no tratamento do tumor venéreo transmissível frente à caracterização citomorfológica / Vincristine sulfate in the treatment of tumor venereal front of the characterization cytomorphological
O tumor venéreo transmissível (TVT) é uma das neoplasias mais freqüentes em cães no Brasil. Trata-se de uma neoplasia sexualmente transmissível, através de um mecanismo de transplantação de células tumorais viáveis, apresenta alta incidência entre cães de ambos os sexos em idade reprodutiva, tendo grande ocorrência em ambientes de alta concentr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/12/2009
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24. Vincristine delays gastric emptying and gastrointestinal transit of liquid in awake rats
We evaluated the effects of vincristine on the gastrointestinal (GI) motility of awake rats and correlated them with the course of vincristine-induced peripheral neuropathy. Vincristine or saline was injected into the tail vein of male Wistar rats (180-250 g) on alternate days: 50 µg/kg (5 doses, N = 10), 100 µg/kg (2, 3, 4 and 5 doses, N = 49) or 150 µg/
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-06