Vertebrate Host
Mostrando 1-12 de 164 artigos, teses e dissertações.
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1. Effect of phospholipase A2 inhibitors during infection caused by Leishmania (Leishmania) amazonensis
Abstract Background: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive inside immune cells. Despite the role of the enzyme Phospholipase A2 (PLA2) in prostaglandins production, few studies have inve
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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2. Characterisation of the vascular pathology in Sigmodon hispidus (Rodentia: Cricetidae) following experimental infection with Angiostrongylus costaricensis (Nematoda: Metastrongylidae)
BACKGROUND Angiostrongylus costaricensis is a nematode that causes human abdominal angiostrongyliasis, a disease found mainly in Latin American countries and particularly in Brazil and Costa Rica. Its life cycle involves exploitation of both invertebrate and vertebrate hosts. Its natural reservoir is a vertebrate host, the cotton rat Sigmodon hispidus. The
Mem. Inst. Oswaldo Cruz. Publicado em: 06/04/2017
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3. A Microtus fortisprotein, serum albumin, is a novel inhibitor of Schistosoma japonicumschistosomula
Schistosomiasis is an endemic parasite disease and praziquantel is the only drug currently in use to control this disease. Experimental and epidemiological evidence strongly suggests that Microtus fortis( Mf) is a naturally resistant vertebrate host of Schistosoma japonicum. In the present study, we found that Mfserum albumin ( Mf-albumin) and the conditione
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-11
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4. Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal
The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s. In the present study, phlebotomine and canine surveys were conducted to identify sandfly blood meal sources and to update the occurrence of Leishmania infec
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-06
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5. Temporal differences in blood meal detection from the midguts of Triatoma infestans
We used genus/species specific PCRs to determine the temporal persistence of host DNA in Triatoma infestans experimentally fed on blood from six common vertebrate species: humans, domestic dogs, guinea pigs, chickens, mice, and pigs. Twenty third or fourth instar nymphs per animal group were allowed to feed to engorgement, followed by fasting-maintenance in
Revista do Instituto de Medicina Tropical de São Paulo. Publicado em: 2012-04
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6. Análise de uma heme oxigenase funcional em Trypanosoma cruzi / Heme oxygenase analysis in Trypanosoma cruzi
Trypanosoma cruzi, the ethiologic agent of Chagas disease, is transmitted through triatomine vectors during their blood-meal on vertebrate host. These hematophagous insects ingest blood about 6 to 12 times its original weight, reaching in a single meal about 10 mM heme bound to hemoglobin. Heme (iron protoporphyrin IX) is an important molecule in metabolism
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2011
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7. Susceptibility and morbidity between male and female Swiss mice infected with Angiostrongylus costaricensis = Susceptibilidade e morbidade entre camundongos Swiss machos e fêmeas infectados com Angiostrongylus costaricensis / Susceptibilidade e morbidade entre camundongos Swiss machos e fêmeas infectados com Angiostrongylus costaricensis
The gender of vertebrate hosts may affect the outcome of parasitic infections. An experimental murine infection with Angiostrongylus costaricensis was followed with determinations of body weight, fecal larval elimination, number and length of adult worms, number of macroscopic intestinal lesions, and mortality. Groups of male and female Swiss mice were infec
Publicado em: 2011
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8. Caracterização fisiológica e genética do transporte de arginina em Leishmania (Leishmania) amazonensis / Physiologic and genetic characterization of arginine transport in Leishmania (Leishmania) amazonensis
Protozoan of genus Leishmania are digenetic parasites that present a stage in the life in insect gut (promastigotes) and an intracellular phase (amastigotes) inside vertebrate host macrophages. The study of L-arginine influx consists in an interesting matter, since the amino acid is used on NO production pathway (the main macrophage microbial pathway) but ar
Publicado em: 2011
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9. Avaliação do efeito tripanocida do eupomatenóide-5 por meio de abordagens de biologia celular e bioquímica : um possível mecanismo de ação
Chagas disease is considered a neglected disease that affects millions of people, but does not have an appropriate and effective treatment. The etiologic agent is the protozoan Trypanosoma cruzi that presents a complex life cycle alternating between a vertebrate host and an invertebrate. In the search for more effective and less toxic drugs, the research for
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2010
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10. Transmission blocking vaccines to control insect-borne diseases: a review
Insect-borne diseases are responsible for severe mortality and morbidity worldwide. As control of insect vector populations relies primarily on the use of insecticides, the emergence of insecticide resistance as well to unintended consequences of insecticide use pose significant challenges to their continued application. Novel approaches to reduce pathogen t
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-02
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11. Reprodução e cultivo de bivalves límnicos ameaçados de extinção: uma estratégia para a conservação do gênero Diplodon (Spix, 1827) (Mollusca, Hyriidae) / Reproduction and cultivation of threatened freshwater mussels: a strategy for the conservation of the genus (Spix, 1827) (Mollusca, Hyriidae)
The freshwater mussels, or naides of the order Unionoida, representing the largest radiation of the bivalves in freshwater, with six families, 181 genera and 800 species, are found on all continents, and currently represent the group of freshwater animals in higher risk of extinction. The most dramatic decline and extinction of freshwater mussels are the mod
Publicado em: 2010
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12. ATIVIDADE LEISHMANICIDA DE DERIVADOS AMINOQUINOLINICOS E EFEITO IMUNOMODULATÓRIO EM MACRÓFAGOS PERITONEAIS INFECTADOS COM LEISHMANIA AMAZONENSIS E L. MAJOR
The leishmaniasis are parasitic-infection diseases that affect 12 million people in 88 countries, it remains a serious public health problem worldwide, including in Brazil. This disease is caused by different Leishmania species, which invade and multiply within macrophages in vertebrate host. No vaccine exists yet and chemotherapy has been based mainly in pe
Publicado em: 2010