Vanilloid
Mostrando 13-24 de 54 artigos, teses e dissertações.
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13. Differentiation of autonomic reflex control begins with cellular mechanisms at the first synapse within the nucleus tractus solitarius
Visceral afferents send information via cranial nerves to the nucleus tractus solitarius (NTS). The NTS is the initial step of information processing that culminates in homeostatic reflex responses. Recent evidence suggests that strong afferent synaptic responses in the NTS are most often modulated by depression and this forms a basic principle of central in
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-04
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14. Participação de fibras sensoriais na resposta edematogenica induzida pela enterotoxina estafilococica do tipo B em camundongos
In this study, we investigated the participation of sensory fibers in the mouse paw oedema induced by staphylococcãI enterotoxin type B (SEB; 25 Ilg/paw). The NK1 receptor antagonist SR140333 (120 nmolJkg, s.c. + 120 nmolJkg, i.v.) significantly inhibited the plasma protein extravasation and oedema formation induced by SEB (37 and 35%, respectively). The oe
Publicado em: 1999
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15. Interaction between vanilloid receptors and purinergic metabotropic receptors: Pain perception and beyond
The National Academy of Sciences.
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16. Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells
The National Academy of Sciences.
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17. Deletion of vanilloid receptor 1_expressing primary afferent neurons for pain control
Control of cancer, neuropathic, and postoperative pain is frequently inadequate or compromised by debilitating side effects. Inhibition or removal of certain nociceptive neurons, while retaining all other sensory modalities and motor function, would represent a new therapeutic approach to control severe pain. The enriched expression of transient receptor pot
American Society for Clinical Investigation.
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18. On the value of nuclear and mitochondrial gene sequences for reconstructing the phylogeny of vanilloid orchids (Vanilloideae, Orchidaceae)
Oxford University Press.
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19. Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain
BioMed Central.
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20. Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
The cloned vanilloid receptor VR1 has attracted recent attention as a molecular integrator of painful stimuli on primary sensory neurons. The existence of vanilloid-sensitive neurons in the brain is, however, controversial. In this study, we have used an antibody and a complementary RNA probe to explore the distribution of neurons that express VR1 in rat and
The National Academy of Sciences.
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21. An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
The vanilloid receptor VR1 is a nonselective cation channel that is most abundant in peripheral sensory fibers but also is found in several brain nuclei. VR1 is gated by protons, heat, and the pungent ingredient of “hot” chili peppers, capsaicin. To date, no endogenous compound with potency at this receptor comparable to that of capsaicin has been identi
The National Academy of Sciences.
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22. Immunological role of neuronal receptor vanilloid receptor 1 expressed on dendritic cells
Capsaicin (CP), the pungent component of chili pepper, acts on sensory neurons to convey the sensation of pain. The CP receptor, vanilloid receptor 1 (VR1), has been shown to be highly expressed by nociceptive neurons in dorsal root and trigeminal ganglia. We demonstrate here that the dendritic cell (DC), a key cell type of the vertebrate immune system, expr
National Academy of Sciences.
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23. The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat
The recently cloned rat vanilloid receptor, VR1, can be activated by capsaicin, acid, and heat. To determine the molecular mechanisms facilitating channel opening in response to these stimuli, VR1 and six channels containing charge neutralization point mutations surrounding the putative channel pore domain were expressed and characterized in Xenopus lae
The National Academy of Sciences.
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24. Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors
The arterial baroreceptor is critically involved in the autonomic regulation of homoeostasis. The transient receptor potential vanilloid 1 (TRPV1) receptor is expressed on both somatic and visceral sensory neurons. Here, we examined the TRPV1 innervation of baroreceptive pathways and its functional significance in the baroreflex. Resiniferatoxin (RTX), an ul
The American Society for Pharmacology and Experimental Therapeutics.