1. ANALYSIS OF BENZODIAZEPINES IN PLASMA SAMPLES BY DLLME AND LC-DAD: CRITICAL ASPECTS, FLAWS AND ISSUES ENCOUNTERED - A DISCUSSION

Dispersive liquid-liquid microextraction (DLLME) is a fast and simple technique and applicable procedure for the analysis of xenobiotics in different biological matrices. We have developed a DLLME method for the determination of benzodiazepines in plasma samples using liquid chromatography-diode-array detection (LC-DAD). During method validation, relative st

Química Nova. Publicado em: 2022

2. Nomogram for predicting post-traumatic hydrocephalus after decompressive craniectomy for traumatic brain injury

SUMMARY OBJECTIVE: This study aimed to develop and validate a practical nomogram to predict the occurrence of post-traumatic hydrocephalus in patients who have undergone decompressive craniectomy for traumatic brain injury. METHODS: A total of 516 cases were enrolled and divided into the training (n=364) and validation (n=152) cohorts. Optimal predictors w

Revista da Associação Médica Brasileira. Publicado em: 2022

3. Translation, Cultural Adaptation and Validation to Brazilian Portuguese of the Tinnitus Functional Index Questionnaire

Abstract Introduction Tinnitus affects a large portion of the world’s population. There are several questionnaires being used for the evaluation of the severity of tinnitus and its impact in quality of life; however, they do not measure treatment-related changes. So, a new self-reported questionnaire was developed, the Tinnitus Functional Index (TFI), whi

International Archives of Otorhinolaryngology. Publicado em: 2022

4. Simultaneous Quantification of Amorphous and Crystalline Valsartan in Tablets Using Raman Spectroscopy and Chemometrics Tools

Valsartan is an antihypertensive active pharmaceutical ingredient (API), it is used in the amorphous state in the commercial products. As amorphous materials are metastable, amorphous valsartan can crystallize to valsartan E, promoting changes in the dissolution and bioavailability of the drug. Tablets containing metastable forms of APIs need special conditi

Journal of the Brazilian Chemical Society. Publicado em: 2022

5. Translation and Validation of the Indonesian MD Anderson Dysphagia Inventory (MDADI) in Head and Neck Cancer Patients with Swallowing Disorders

Abstract Introduction Dysphagia is common in head and neck cancer patients; it is associated with significant morbidity, including quality of life. Several instruments can be used to assess the quality of life of dysphagia patients, including the M.D Anderson dysphagia inventory (MDADI) questionnaire, which is sufficiently valid and reliable to improve the

International Archives of Otorhinolaryngology. Publicado em: 2022

6. Letter to the editor: “Validation of the Connecticut olfactory test (CCCRC) adapted to Brazil”

Brazilian Journal of Otorhinolaryngology. Publicado em: 2022

7. Validation and cross-cultural adaptation of the 10-Item Victimization Scale into Brazilian Portuguese for transgenders: preliminary findings

Brazilian Journal of Psychiatry. Publicado em: 2022

8. Pediatric Functional Constipation Questionnaire-Parent Report (PedFCQuest-PR): development and validation

Abstract Objective: Developing and validating a disease-specific instrument in the Brazilian Portuguese language to assess the Health-Related Quality of Life of children with functional constipation, applied to parents/caregivers. Methods: The process of developing the questionnaire was carried out in the following steps: items generation concerning functi

Jornal de Pediatria. Publicado em: 2022

9. Danish Validation of a Retronasal Olfactory Powder Test and Development of a Novel Quick Retronasal Olfactory Test

Abstract Introduction Quality of life is closely linked to retronasal olfactory function. Familiarity with odors vary, so tests need validation. Testing can be time-consuming, so a quick test and a thorough test are needed for clinical and research settings. Objectives The objectives of this study were to validate the original retronasal powder olfactory t

International Archives of Otorhinolaryngology. Publicado em: 2022

10. Cross-Cultural Adaptation, Validation, and Arabic Translation of the Eustachian Tube Dysfunction Questionnaire (ETDQ-7)

Abstract Introduction The Eustachian Tube Dysfunction Patient Questionnaire (ETDQ-7) scale is used to assess the effectiveness of the treatment and to determine the severity of the eustachian tube dysfunction (ETD). There is currently no validated Arabic version of the ETDQ-7. Objectives The aim of the present study is to test the validity and the reliabil

International Archives of Otorhinolaryngology. Publicado em: 2022

11. Cultural adaptation and validation of the quality of life questionnaire for patients with actinic keratosis (AKQoL-BR) to Brazilian Portuguese

Anais Brasileiros de Dermatologia. Publicado em: 2022

12. Translation and validation of the Tinnitus Primary Function Questionnaire into Brazilian Portuguese

Abstract Objective: In this study, the Tinnitus Primary Function Questionnaire was translated, culturally adapted and validated for Brazilian Portuguese. Methods: This study was carried out in two stages. First, a prospective study of translation and cultural adaptation was carried out with a group of 20 patients. The questionnaire was translated, revised

Brazilian Journal of Otorhinolaryngology. Publicado em: 2022