Uterine Cervical Dysplasia
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Aspectos preditivos da progressão da lesão de NIC 1 em biopsias do colo uterino : estudo comparativo entre o metodo da hibridização in situ e a expressão do Ki67, avaliada por metodos morfologicos quantitativos / NIC lesion progression in cervical biopsies : predictive value of in situ hybridization technique versus Ki67 expression, as evaluated by quantitative morphological methods
As Neoplasias Intra-epiteliais Cervicais (NIC) são precursoras do carcinoma do colo uterino e, em sua maioria, causadas pelos vírus do Papiloma Humano (HPV) de alto risco oncogênico. A maior parte das NIC1 regride, mas cerca de 15% pode progredir e a integração viral ao genoma da célula tem papel importante neste evento. A hibridização in situ (HIS)
Publicado em: 2010
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2. Citologia cérvico-vaginal inflamatória associada com atividade da doença no lúpus eritematoso sistêmico juvenil / Inflammatory cervicovaginal cytology is associated with disease activity in juvenile systemic lupus erythematosus
Objective: To evaluate cervicovaginal cytology in adolescents with juvenile systemic lupus erythematosus (JSLE) and to compare them to controls. Material and methods: Fifty-two female adolescents with JSLE (American College of Rheumatology criteria) were compared to 52 age-matched healthy controls. All Pap smears were evaluated by the same cytopathologist bl
Publicado em: 2007
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3. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix.
We have chosen tumors of the uterine cervix as a model system to identify chromosomal aberrations that occur during carcinogenesis. A phenotype/genotype correlation was established in defined regions of archived, formalin-fixed, and hematoxylin/eosin-stained tissue sections that were dissected from normal cervical epithelium (n = 3), from mild (n = 4), moder
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4. Epithelial membrane antigen in cells from the uterine cervix: immunocytochemical staining of cervical smears.
Smears made from cervical scrapes have been stained immunocytochemically for epithelial membrane antigen using a polyclonal antiserum and two monoclonal antibodies. With the polyclonal antiserum malignant cells and those showing dysplasia consistently expressed the antigen. Normal cells were generally negative, with the exception of some metaplastic cells. T
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5. Cloning and characterization of the DNA of a new human papillomavirus from a woman with dysplasia of the uterine cervix.
A previous analysis of 121 female genital tract lesions from the United States and South America had revealed that a large number contained DNA sequences that were weakly homologous to a panel of human papillomavirus (HPV) probes. The DNA sequences of one of these viruses have been molecularly cloned and shown to be a new type of HPV which is called HPV 31.
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6. Tenascin in human papillomavirus associated lesions of the uterine cervix.
The immunohistochemical expression of tenascin was studied in 80 morphologically diagnosed condylomas and cervical intraepithelial neoplasia (CIN) lesions. The results were compared with the human papillomavirus (HPV) DNA subtype, which was determined by HPV dot blot and in situ hybridisation. Tenascin mRNA synthesis was also determined in 10 selected cases