Urethane Anesthesia
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Effects of silibinin and ethanol on skeletal muscle ischemia-reperfusion injury
PURPOSE: To investigate the potential beneficial effect of silibinin in ischemia-reperfusion injury (IRI) of skeletal muscle. METHODS: Under urethane anesthesia, four experimental groups were established in Balb/c mice: I) Sham-control, II) IRI (Tourniquet-induced) (2+1 h), III) IRI+ethanol (10%), and IV) IRI+silibinin (50 mg/kg/IP). The viability of muscle
Acta Cir. Bras.. Publicado em: 2013-03
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2. Plasticidade sináptica no córtex pré-frontal induzida por estimulação do tálamo mediodorsal de ratos in vivo: efeitos da modulação colinérgica muscarínica e nicotínica / Prefrontal cortical synaptic plasticity induced by stimulation of the rat mediodorsal thalamus in vivo: effects of cholinergic muscarinic and nicotinic modulation
O núcleo talâmico mediodorsal (Tmd) e o córtex pré-frontal (CPF) comunicam-se mutuamente, formando um circuito envolvido em funções executivas e transtornos psiquiátricos. As funções executivas estão sujeitas aos níveis de alerta gerados pela atividade oscilatória talamocortical, que por sua vez é controlada pela transmissão colinérgica. Possi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/08/2012
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3. Acute tryptophan administration impairs cortical spreading depression propagation in REM sleep deprived and non-deprived adult rats
The enhanced availability of tryptophan in the brain, as a consequence of exogenous tryptophan administration, can increase neuronal serotonin synthesis and this can interfere with brain function. REM sleep deprivation (D) constitutes another external factor that can change brain excitability, facilitating, in some cases, the manifestation of neurological di
Psychology & Neuroscience. Publicado em: 2009-12
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4. Efeitos neuromusculares do atracurio e do rocuronio em ratos pre-tratados com carbamazepina e fenobarbital : estudo in vitro e in vivo / Neuromuscular effects of atracurium and rocuronium in pre treated rats with carbamazepine and phenobarbital : study in vitro e in vivo
Atracurium (ATC) and rocuronium (ROC) are neuromuscular blockers of intermediate action. In this study, the neuromuscular effects had been investigated in vitro and in vivo in treated rats, by gavage (7d), with the anticonvulsantes (AC) carbamazepine (CBZ, 40 mg/kg) and phenobarbital (FB, 20 mg/kg) and sacrificed on the eight day, under anesthesia with ureth
Publicado em: 2007
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5. Cardiovascular responses to microinjections of GABA or anesthetics into the rostral ventrolateral medulla of conscious and anesthetized rats
The rostral ventrolateral medulla (RVLM) contains neurons involved in tonic and reflex control of arterial pressure. We describe the effects of gamma-aminobutyric acid (GABA) and anesthetics injected into the RVLM of conscious and urethane (1.2 g/kg, iv) anesthetized Wistar rats (300-350 g). In conscious rats, bilateral microinjection of GABA (50 nmol/200 nl
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-09
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6. Cardiovascular and respiratory responses to microinjection of L-glutamate into the caudal pressor area in conscious and anesthetized rats
The role of the caudal pressor area (CPA) in the maintenance of vasomotor tonus in anesthetized and decerebrate animals has been clearly established. In conscious animals, however, the participation of CPA in the cardiovascular control remains to be fully elucidated. In the present study, unilateral L-glutamate (L-Glu) (10 and/or 20 nmol/70 nl) microinjectio
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-12
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7. Induction of Fos protein immunoreactivity by spinal cord contusion
The objective of the present study was to identify neurons in the central nervous system that respond to spinal contusion injury in the rat by monitoring the expression of the nuclear protein encoded by the c-fos gene, an activity-dependent gene, in spinal cord and brainstem regions. Rats were anesthetized with urethane and the injury was produced by droppin
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-05
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8. The Neurogenic Vasoconstrictor Effect of Digitalis on Coronary Vascular Resistance
The coronary vasoconstrictor properties of digitals were evaluated in 61 anesthetized, openchest dogs after coronary sinus cannulation and under conditions of a constant heart rate (atrioventricular pacing) and near-constant blood pressure. The contribution of alpha adrenergic receptor stimulation to the digitalis-induced increase in coronary vascular resist
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9. Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking α1G-subunit of T-type calcium channels
T-type calcium channels have been implicated as a pacemaker for brain rhythms during sleep but their contribution to behavioral states of sleep has been relatively uncertain. Here, we found that mice lacking α1G T-type Ca2+ channels showed a loss of the thalamic delta (1–4 Hz) waves and a reduction of sleep spindles (7–14 Hz), whereas slow (<1 Hz) rhyth
National Academy of Sciences.
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10. Effects of 17β-Estradiol on Responses of Viscerosomatic Convergent Thalamic Neurons in the Ovariectomized Female Rat
Ovarian hormones have been shown to exert multiple effects on CNS function and viscerosomatic convergent activity. Ovariectomized (OVX) female rats were used in the present study to examine the long-term effects of proestrus levels of 17β-estradiol (EB) delivered by a 60-day time-released subcutaneous pellet on the response properties of viscerosomatic conv
American Physiological Society.
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11. Segmental Neuropathic Pain Does Not Develop in Male Rats with Complete Spinal Transections
In a previous study using male rats, a correlation was found between the development of “at-level” allodynia in T6-7 dermatomes following severe T8 spinal contusion injury and the sparing of some myelinated axons within the core of the lesion epicenter. To further test our hypothesis that this sparing is important for the expression of allodynia and the
Mary Ann Liebert.