Triple Null Lines
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Lipoxygenase activities during development of root and nodule of soybean.
The objective of this work was to evaluate root and nodule soybean lipoxygenases in Doko cultivar and in a near isogenic line lacking seed lipoxygenases, inoculated and uninoculated with Bradyrhizobium elkanii. The lipoxygenase activities from roots collected at 3, 5, 9, 13, 18 and 28 days post-inoculation and from nodules collected at 13, 18 and 28 days pos
Pesquisa Agropecuária Brasileira. Publicado em: 2011
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2. Insufficient Folding of Type IV Collagen and Formation of Abnormal Basement Membrane-like Structure in Embryoid Bodies Derived from Hsp47-Null Embryonic Stem CellsD⃞
Hsp47 is a molecular chaperone that specifically recognizes procollagen in the endoplasmic reticulum. Hsp47-null mouse embryos produce immature type I collagen and form discontinuous basement membranes. We established Hsp47-/- embryonic stem cell lines and examined formation of basement membrane and production of type IV collagen in embryoid bodies, a model
The American Society for Cell Biology.
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3. Related to Ubiquitin 1 and 2 Are Redundant and Essential and Regulate Vegetative Growth, Auxin Signaling, and Ethylene Production in Arabidopsis
Related to Ubiquitin (RUB)/Nedd8 is a ubiquitin-like protein that covalently attaches to cullins, a subunit of the SCF (for Skp, Cdc53p/Cul1, and F-box protein) complex, an E3 ubiquitin ligase, and has been shown to be required for robust function of the complex. The effects of reducing protein levels for two Rub proteins, RUB1 and RUB2, were characterized i
American Society of Plant Biologists.
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4. A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis
In human prostate cancer, the frequent down-regulation of p27kip1 protein expression is correlated with poor clinical outcome, yet p27kip1 rarely undergoes mutational inactivation. Here, we investigate the consequences of reducing or eliminating p27kip1 function for prostate carcinogenesis in the context of a mouse modeling lacking the Nkx3.1 homeobox gene a
National Academy of Sciences.
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5. Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(α1*0101,β1*0401) transgenic mice
Glutamic acid decarboxylase isoform 2 (GAD65; EC 4.1.1.15) has been identified as a key target autoantigen of insulin-dependent diabetes mellitus (IDDM). IDDM is genetically associated with the major histocompatibility complex (MHC), and particular alleles from the HLA-DQ and HLA-DR loci contribute to disease. Among DR4 subtypes, HLA-DRB1*0401, HLA-DRB1*0402
The National Academy of Sciences of the USA.
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6. Arabidopsis Seedling Growth Response and Recovery to Ethylene. A Kinetic Analysis1
Responses to the plant hormone ethylene are mediated by a family of five receptors in Arabidopsis that act in the absence of ethylene as negative regulators of response pathways. In this study, we examined the rapid kinetics of growth inhibition by ethylene and growth recovery after ethylene withdrawal in hypocotyls of etiolated seedlings of wild-type and et
American Society of Plant Biologists.
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7. EBNA3A Association with RBP-Jκ Down-Regulates c-myc and Epstein-Barr Virus-Transformed Lymphoblast Growth
Epstein-Barr virus nuclear antigen protein 3A (EBNA3A) is one of four EBNAs (EBNA-2, EBNALP, EBNA3A, and EBNA3C) through the cellular DNA sequence-specific transcription factor RBP-Jκ/CBF-1/CSL and are essential for conversion of primary B lymphocytes to lymphoblastoid cell lines (LCLs). In the present study, we investigated the effects of EBNA3A on EBNA2 a
American Society for Microbiology.