Triazol
Mostrando 1-12 de 80 artigos, teses e dissertações.
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1. Synthesis of Eugenol-Fluorinated Triazole Derivatives and Evaluation of Their Fungicidal Activity
Eugenol (C10H12O2, 4-allyl-2-methoxyphenol) is a phenolic natural product that has several biological activities and possibilities of applications. It is herein described the synthesis of eugenol-fluorinated triazole derivatives and evaluation of their fungicidal activity. The reaction of eugenol with epichlorohydrin resulted in the preparation of (±)-2-((4
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Inhibition of Acetylcholinesterase by Coumarin-Linked Amino Acids Synthetized via Triazole Associated with Molecule Partition Coefficient
A previous study for the identification of acetylcholinesterase (AChE) inhibitors demonstrated that the hybrid between tyrosol, the 1,2,3-triazole nucleus, and the coumarin group, namely 7-({1-[2-(4-hydroxyphenyl)ethyl]-1H-1,2,3-triazol-4-yl}methoxy)-4-methyl-2H-chromen-2-one (10), has a high enzyme inhibitory activity. Here, we synthesized analogues of 10 v
J. Braz. Chem. Soc.. Publicado em: 2021-03
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3. Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity
Carpotroche brasiliensis is a tree native to Brazil, belonging to the family Flacurtiaceae, whose seeds contain a group of cyclopentenyl fatty acids: gorlic (12%), chaulmugric (27%), and hydnocarpic (48.7%). These compounds are considered the main therapeutic agents in the treatment of leprosy. In the present study, a series of novel triazole compounds were
J. Braz. Chem. Soc.. Publicado em: 2020-12
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4. Performance of fungicides on the control of fusarium head blight (Triticum aestivum L.) and deoxynivalenol contamination in wheat grains
RESUMO A giberela é considerada uma doença de difícil controle, num cenário de dificuldades no seu controle químico e pela agressividade do patógeno em produzir toxinas. Diante disso, o objetivo do estudo foi verificar se fungicidas de distintos grupos químicos, isolados ou em mistura são eficazes no controle de giberela e na redução da contaminaç
Summa phytopathol.. Publicado em: 17/01/2020
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5. Morphology of yellow passion fruit seedlings submitted to triazole induced growth inhibition
RESUMO A restrição do vigor vegetativo de mudas pode ser uma estratégia para otimização da modulação frente à estresses bióticos e abióticos após o transplantio. O objetivo desse estudo foi verificar se os parâmetros morfológicos de mudas de maracujazeiro amarelo (Passiflora edulis) são afetados pela restrição do crescimento com aplicação d
Ciênc. agrotec.. Publicado em: 20/12/2019
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6. Streamlined Synthesis of 6-((1H-1,2,3-Triazol-4-yl)methyl)-1H-pyrrolo [3,4-d]pyridazin-1-one System via Sequential N-Alkylation, CuAAC, and [4 + 2] Cyclization Reactions
An efficient sequential three-step reaction methodology for the synthesis of three new series-1-(prop-2-yn-1-yl)-1H-pyrroles, methyl 4-acetyl-1-((1H-1,2,3-triazol-4-yl)methyl)-1H-pyrrole-3-carboxylates and 6-((1H-1,2,3-triazol-4-yl)methyl)-2,6-dihydro-1H-pyrrolo[3,4-d]pyridazin-1-ones-is reported. The methodology comprises: (i) N-alkylation reactions of poly
J. Braz. Chem. Soc.. Publicado em: 23/05/2019
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7. Synthesis of 1,2,3-Triazole Derivatives of 4,4'-Dihydroxybenzophenone and Evaluation of Their Elastase Inhibitory Activity
The present investigation describes the synthesis of a series of novel triazole derivatives from 4,4'-dihydroxybenzophenone along with their elastase inhibitory activity. The 1,2,3-triazoles were obtained via the copper(I)-catalyzed azide-alkyne cycloaddition reaction (CuAAC), also known as click reaction, between bis(4-(prop-2-yn-1-yloxy))benzophenone and s
J. Braz. Chem. Soc.. Publicado em: 2019-01
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8. Studies on new substituted pyridazinones: synthesis and biological evaluation
We report herein the synthesis and pharmacological evaluation of a new series of 6-aryl-2-(imidazol-1-yl/1,2,4-triazol-1-yl)-2-methyl-4,5-dihydro-(2H)-pyridazin-3-one (3a-j) as potential anticonvulsant and antitubercular agents. The title compounds were prepared by reacting 6-aryl-4,5-dihydro-(2H)-pyridazin-3-one (2a-e) with formaldehyde and secondary cyclic
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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9. Synthesis and Cytotoxic Evaluation of 1H-1,2,3-Triazol-1-ylmethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diones
ABSTRACT The 1,2-naphthoquinone compound was previously considered active against solid tumors. Moreover, glycosidase inhibitors such as 1,2,3-1H triazoles has been pointed out as efficient compounds in anticancer activity studies. Thus, a series of eleven 1,2-naphthoquinones tethered in C2 to 1,2,3-1H-triazoles 9a-k were designed, synthesized and their cyto
An. Acad. Bras. Ciênc.. Publicado em: 15/02/2018
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10. Sensibilidade de raças de Puccinia triticina, a fungicidas determinada em folhas de trigo destacadas
RESUMO Em experimentos conduzidos em câmara climatizada e laboratório, quantificou-se a ação preventiva, curativa e erradicativa dos fungicidas no controle das raças MFT-MT e TFP-HT de Puccinia triticina. Avaliou-se o efeito dos fungicidas tebuconazol (triazol) e azoxistrobina (estrobilurina), isoladamente. As plântulas foram inoculadas com uma suspens
Summa phytopathol.. Publicado em: 2017-09
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11. Strategies for Molecular Diversification of 2-[Aminoalkyl-(1H-1,2,3-triazol-1- yl)]-1,4-naphthoquinones Using Click Chemistry
Click chemistry-based strategies for the synthesis of 2-amino-alkyl-1,2,3-triazole-1,4-naphthoquinone derivatives make it possible to obtain desired products from 1,4-naphthoquinone (1,4-NQ), and bio-based lawsone, nor-lapachol and lapachol. The first route (Strategy A) starting from 1,4-NQ and amino alcohols, then 2-amino-alkyl-1,4-NQ alcohols, were tosylat
J. Braz. Chem. Soc.. Publicado em: 2017-04
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12. Crystal Structures of 1-Aryl-1H- and 2-Aryl-2H-1,2,3-triazolyl Hydrazones. Conformational Consequences of Different Classical Hydrogen Bonds
The crystal structures of (Z)-1-phenyl-4-[((2-phenylhydrazono)methyl)]-1H-1,2,3-triazole, (Z)-4-[(2-(2,4-dimethylphenyl)hydrazono)methyl]-2-phenyl-2H-1,2,3-triazole, (E)-4-[(2-(2,4-dinitrophenyl)hydrazono)methyl]-2-phenyl-2H-1,2,3-triazole, and (E)-N'-((2-phenyl-2H-1,2,3-triazol-4-yl)methylene)isonicotinohydrazide dihydrate are reported. The formations of (Z
J. Braz. Chem. Soc.. Publicado em: 2016-12