Transgenic
Mostrando 13-24 de 5875 artigos, teses e dissertações.
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13. [PROVISIONAL] Overexpression of rice F-box protein OsFBX322 confers increased sensitivity to gamma irradiation in Arabidopsis
Abstract Ionizing radiation has a substantial effect on physiological and biochemical processes in plants via induction of transcriptional changes and diverse genetic alterations. Previous microarray analysis showed that rice OsFBX322, which encoded a rice F-box protein, was downregulated in response to three types of ionizing radiation: gamma irradiation, i
Genet. Mol. Biol.. Publicado em: 02/09/2019
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14. Comparison of in vitro callus-cultures from transgenic maize AG-5011YG (MON810) and conventional near-isogenic maize AG-5011
Abstract MON810 is a genetically-modified (GM) maize (Zea mays) event commonly employed in insect-resistant GM maize hybrids. GM events obtained by biolistic transformation methods, such as MON810, are generated by insertion of a recombinant gene expression cassette in a random locus of the plant genome, and this process may cause emergent properties besides
Crop Breed. Appl. Biotechnol.. Publicado em: 01/08/2019
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15. Analysis of the physical quality of genetically modified and conventional maize grains in the drying and wetting processes
RESUMO O objetivo deste trabalho foi avaliar a qualidade física dos grãos de milho geneticamente modificados (Herculex 30S31) em função dos processos de secagem e umedecimento em relação ao milho convencional (AG 1051). O delineamento experimental foi o inteiramente casualizado, com esquema fatorial (7x3x2), sete tempos de secagem ou umedecimento (0, 2
Rev. Ciênc. Agron.. Publicado em: 04/07/2019
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16. Edição genética: riscos e benefícios da modificação do DNA humano
Resumo O artigo analisa discussões sobre edição genética humana encontradas em artigos científicos, declarações institucionais e proferidas no International Summit on Gene Editing realizado em 2015. Objetiva-se explicitar e refletir sobre argumentos favoráveis e contrários à modificação do DNA. A edição genética pode desenvolver novas terapêu
Rev. Bioét.. Publicado em: 01/07/2019
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17. CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice
Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/delta T cell receptor rearrangement, frequently associated wit
Braz J Med Biol Res. Publicado em: 27/05/2019
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18. An update on the tools for creating transgenic animal models of human diseases – focus on atherosclerosis
Animal models of diseases are invaluable tools of modern medicine. More than forty years have passed since the first successful experiments and the spectrum of available models, as well as the list of methods for creating them, have expanded dramatically. The major step forward in creating specific disease models was the development of gene editing technique
Braz J Med Biol Res. Publicado em: 25/04/2019
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19. In vitro organogenesis and genetic transformation of mandarin cultivars
Resumo A organogênese in vitro das tangerinas Fremont (Citrus clementina x Citrus reticulata), Thomas (Citrus reticulata) e Nules (Citrus clementina) foi avaliada visando a otimizar o protocolo de regeneração para aplicação da transformação genética. O uso de explantes derivados de epicótilo resultou em maior número de explantes responsivos e maio
Rev. Bras. Frutic.. Publicado em: 25/04/2019
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20. Protein-protein interactions of the nicotinamide/nicotinate mononucleotide adenylyltransferase of Leishmania braziliensis
BACKGROUND Nicotinamide adenine dinucleotide (NAD) plays a central role in energy metabolism and integrates cellular metabolism with signalling and gene expression. NAD biosynthesis depends on the enzyme nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT; EC: 2.7.7.1/18), in which converge the de novo and salvage pathways. OBJECTIVE The pu
Mem. Inst. Oswaldo Cruz. Publicado em: 21/03/2019
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21. Transgênicos e o princípio de equivalência substancial
RESUMO Objetivamos discutir os principais argumentos que estão envolvidos no debate sobre a cientificidade do Princípio de Equivalência Substancial (PES), que afirma serem os OGM quimicamente equivalentes aos organismos selecionados pelas técnicas tradicionais de melhoramento, não requerendo, portanto, estudos toxicológicos adicionais. Problematizamos
Estud. av.. Publicado em: 2019-01
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22. Protective effect of luteolin on the transgenic Drosophila model of Parkinson’s disease
In the present study we have studied the effect of 25, 50, 75 and 100 µM of luteolin on the transgenic Drosophila expressing human alpha synuclein. The doses of luteolin were established in diet and the PD flies were allowed to feed on it for 24 days. After 24 days of exposure the flies were assayed for climbing assay, oxidative stress markers, caspase-3 &
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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23. Bioenergetics Potential of RR2 PRO Transgenic Soybean Subjected to Application of Herbicides Isolated and in Combination
ABSTRACT In Brazil, there are several crops producing oil for biofuel production, such as canola, sunflower, peanut, cotton, castor bean, soybean, among others. There are parameters that indicate the energetic and economic viability for the production of biofuels, and that can be applied, for example, in transgenic soybeans. The present study aimed to evalua
Braz. arch. biol. technol.. Publicado em: 29/11/2018
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24. Phytoene Synthase Gene ( PSY ) from Sweet Potato ( Ipomoea batatas Lam . ) Enhances Tolerance to Abiotic Stress
ABSTRACT Phytoene synthase (PSY) is the rate-limiting enzyme for carotenoid biosynthesis. To date, several studies focused on PSY genes in the context of abiotic stress responses. In this study, two phytoene synthase encoding genes, IbPSY1 and IbPSY2, were identified from a published transcriptome and bioinformatic analysis showed that they shared conserved
Braz. arch. biol. technol.. Publicado em: 14/11/2018