Transgenic Cells
Mostrando 1-12 de 2312 artigos, teses e dissertações.
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1. CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice
Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/delta T cell receptor rearrangement, frequently associated wit
Braz J Med Biol Res. Publicado em: 27/05/2019
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2. Phytoene Synthase Gene ( PSY ) from Sweet Potato ( Ipomoea batatas Lam . ) Enhances Tolerance to Abiotic Stress
ABSTRACT Phytoene synthase (PSY) is the rate-limiting enzyme for carotenoid biosynthesis. To date, several studies focused on PSY genes in the context of abiotic stress responses. In this study, two phytoene synthase encoding genes, IbPSY1 and IbPSY2, were identified from a published transcriptome and bioinformatic analysis showed that they shared conserved
Braz. arch. biol. technol.. Publicado em: 14/11/2018
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3. The role of fetal-maternal microchimerism as a natural-born healer in integrity improvement of maternal damaged kidney
ABSTRACT Purpose: To identify the fetal stem cell (FSC) response to maternal renal injury with emphasis on renal integrity improvement and Y chromosome detection in damaged maternal kidney. Materials and Methods: Eight non-green fluorescent protein (GFP) transgenic Sprague-Dawley rats were mated with GFP-positive transgenic male rats. Renal damage was indu
Int. braz j urol.. Publicado em: 2018-06
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4. Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair
Abstract Background Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve grafting is used. However, these surgical techniques result in nerve regeneration at highly variable degrees. It is thus very importa
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/05/2018
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5. Bone marrow cell migration to the heart in a chimeric mouse model of acute chagasic disease
BACKGROUND Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease. Although there is some evidence for the beneficial effect of bone marrow-derived cells in chagasic disease, the mechanisms underlying their effects in the heart are unknown. Reports have
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-08
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6. microRNAs and the mammary gland: a new understanding of gene expression
MicroRNAs (miRNAs) have been identified in cells as well as in exosomes in biological fluids such as milk. In mammary gland, most of the miRNAs studied have functions related to immunity and show alterations in their pattern of expression during lactation. In mastitis, the inflammatory response caused by Streptococcus uberis alters the expression of miRNAs t
Genet. Mol. Biol.. Publicado em: 25/10/2013
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7. Participação das selectinas nas interações entre células angiogênicas da medula óssea e endotélio de músculos isquêmicos de membros inferiores em modelo murino.
The stimulation of vascular growth by angiogenic stem cells transplantation is a promising alternative for the treatment of PAD. Adhesive mechanisms governing progenitor/stem cell trafficking through the microcirculation of ischemic muscles are broadly unknown. The aim of this work was to evaluate the involvement of selectins on interactions between transpla
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/05/2011
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8. Modelos para a produção de eritropoietina recombinante humana in vivo e in vitro com vetores plasmideais em ovinos / Models for the production of human recombinant erythropoietin in vivo and in vitro with plasmidial vectors in ovine
Some post-translational modifications are necessary for the production of biopharmaceutical proteins, such as recombinant human erythropoietin (rhEPO), with a good specific action and a high biological activity. These modifications are obtained only by bioreactors based on eukaryotic cell as mammary cells. Bioreactors, in vivo or in vitro, with this kind of
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2011
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9. Transformação de plantas.
ABSTRACT: During centuries mankind plants to obtain cultivars with superior characteristics. However, conventional methods of plant breeding present limitations. The development of transformation methods created possibilities of great progresses in plant breeding because it offers the opportunity to introduce exogenous genes into superior cultivars to obtain
Planaltina. Publicado em: 2011
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10. Interação molecular planta-nematóide.
ABSTRACT: The endoparasitic sedentary phytonematodes of genera Heterodera, Globodera (known as cyst nematodes, CN) and Meloidogyne (the root-knot nematodes, RKN) are major crop phytopathogens, causing estimated losses of US$ 125 billion annually in the world. These plant-parasitic nematodes share some parasitism mechanisms, which ensure host-tissue invasion
Planaltina. Publicado em: 2011
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11. Effect of aging and oral tolerance on dendritic cell function
Oral tolerance can be induced in some mouse strains by gavage or spontaneous ingestion of dietary antigens. In the present study, we determined the influence of aging and oral tolerance on the secretion of co-stimulatory molecules by dendritic cells (DC), and on the ability of DC to induce proliferation and cytokine secretion by naive T cells from BALB/c and
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-01
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12. Expressão do growth and differentiation factor 9 (GDF9) e bone morphogenetic protein 15 (BMP15) in vitro e seu efeito no processo de luteinização em células da granulosa bovinas / Expression of growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) and their effect on in vitro luteinization of bovine granulosa cells
Os sistemas de cultivo de células da granulosa vêm se desenvolvendo com o intuito de assemelhar-se às condições esteroidogênicas encontradas in vivo no folículo ovariano. A remoção do ovócito resulta na luteinização espontânea das células somáticas foliculares, com alteração no padrão esteroidogênico, que também acontece quando estas cél
Publicado em: 2010