Toxins
Mostrando 37-48 de 1831 artigos, teses e dissertações.
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37. Isolation and molecular characterization of Bacillus thuringiensis found in soils of the Cerrado region of Brazil, and their toxicity to Aedes aegypti larvae
ABSTRACT This study investigated the potential of Bacillus thuringiensis isolates obtained in the Cerrado region of the Brazilian state of Maranhão for the biological control of Aedes aegypti larvae. The isolates were obtained from soil samples and the identification of the B. thuringiensis colonies was based on morphological characteristics. Bioassays were
Rev. Bras. entomol.. Publicado em: 2018-01
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38. Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions
Abstract Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin. Crotoxin is a non-covalent heterodimeric neurotoxin constituted of two subunits: an active phospholipase A2 and a chaperone p
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/12/2017
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39. Adhesion and invasion of Clostridium perfringens type A into epithelial cells
ABSTRACT Clostridium perfringens is the causative agent for necrotic enteritis. It secretes the major virulence factors, and α- and NetB-toxins that are responsible for intestinal lesions. The TpeL toxin affects cell morphology by producing myonecrosis, but its role in the pathogenesis of necrotic enteritis is unclear. In this study, the presence of netB an
Braz. J. Microbiol.. Publicado em: 2017-12
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40. Increasing rates of Clostridium difficile infection in Mexican hospitals
Abstract Introduction The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. Methods This was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CD
Braz J Infect Dis. Publicado em: 2017-10
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41. Differentiation of Toxic and Non-Toxic Leaves of Jatropha curcas L. Genotypes by Leaf Spray Mass Spectrometry
Jatropha curcas L. is an oil crop that has been studied as a potential source of biodiesel. A high protein pie is produced as a byproduct of the biodiesel production, which could be used as animal feed. However, the pie has toxic compounds, as phorbol esters and other toxins, which prevents the use as animal feed. For this reason, Embrapa (Brazilian Agricult
J. Braz. Chem. Soc.. Publicado em: 2017-08
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42. Long-term response of different Botulinum toxins in refractory neurogenic detrusor overactivity due to spinal cord injury
ABSTRACT Purpose To assess the response in spinal cord injured patients alternatively treated with different types and dosages of Botulinum neurotoxin type A (BoNT/A) over 15 years. Material and methods Patients who underwent first BoNT/A from 1999-2001 and practiced intermittent catheterization were included. Baseline 3-day bladder diary (BD) and urodyn
Int. braz j urol.. Publicado em: 2017-08
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43. Protein-species quantitative venomics: looking through a crystal ball
Abstract In this paper we discuss recent significant developments in the field of venom research, specifically the emergence of top-down proteomic applications that allow achieving compositional resolution at the level of the protein species present in the venom, and the absolute quantification of the venom proteins (the term “protein species” is used he
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/07/2017
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44. Rattlesnake Crotalus molossus nigrescens venom induces oxidative stress on human erythrocytes
Abstract Background Globally, snake envenomation is a well-known cause of death and morbidity. In many cases of snakebite, myonecrosis, dermonecrosis, hemorrhage and neurotoxicity are present. Some of these symptoms may be provoked by the envenomation itself, but others are secondary effects of the produced oxidative stress that enhances the damage produce
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/07/2017
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45. Biological and molecular properties of yellow venom of the Amazonian coral snake Micrurus surinamensis
Abstract INTRODUCTION: The coral snake Micrurus surinamensis, which is widely distributed throughout Amazonia, has a neurotoxic venom. It is important to characterize the biological and molecular properties of this venom in order to develop effective antitoxins. METHODS: Toxins from the venom of M. surinamensis were analyzed by two-dimensional polyacryla
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-06
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46. Alpha-type phospholipase A2 inhibitors from snake blood
Abstract It is of popular and scientific knowledge that toxins from snake venom (among them the PLA2 and myotoxins) are neutralized by various compounds, such as antibodies and proteins purified from animal blood. Venomous and nonvenomous snakes have PLA2 inhibitory proteins, called PLIs, in their blood serum. One hypothesis that could explain the presence o
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
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47. A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom
Abstract Background Envenomation caused by multiple stings from Africanized honeybees Apis mellifera constitutes a public health problem in the Americas. In 2015, the Brazilian Ministry of Health reported 13,597 accidents (incidence of seven cases per 100,000 inhabitants) with 39 deaths (lethality of 0.25%). The toxins present in the venom, which include m
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
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48. MALDI Imaging Mass Spectrometry of Fresh Water Cyanobacteria: Spatial Distribution of Toxins and Other Metabolites
Cyanobacteria are among the most ancient forms of life, yet they are known to synthesize highly sophisticated defense molecules, such as the highly hepatotoxic cyclic peptides microcystins and nodularins produced by the genera Microcystis, Anabaena and Nodularia. These metabolites are released by cyanobacteria to water environments causing episodes of fatali
J. Braz. Chem. Soc.. Publicado em: 2017-04