Topological Sensitivity Analysis
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Topological derivative-based topology optimization of structures subject to multiple load-cases
AbstractThe topological derivative measures the sensitivity of a shape functional with respect to an infinitesimal singular domain perturbation, such as the insertion of holes, inclusions or source-terms. The topological derivative has been successfully applied in obtaining the optimal topology for a large class of physics and engineering problems. In this p
Lat. Am. j. solids struct.. Publicado em: 2015-05
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2. QSAR Study of the Inhibitors of the Acetyl-CoA Carboxylase 1 and 2 using Bayesian Regularized Genetic Neural Networks: A Comparative Study
Linear and non-linear quantitative structure-activity relationship (QSAR) models were presented for modeling and predicting anti-diabetic activities of a set of inhibitors of acetyl-CoA carboxylase 1 and 2 (ACC1 and ACC2). Different algorithms were utilized to choose the best variables among large numbers of descriptors and then these selected descriptors we
J. Braz. Chem. Soc.. Publicado em: 2015-03
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3. Topological sensitivity analysis for a two-parameter Mooney-Rivlin hyperelastic constitutive model
The Topological Sensitivity Analysis (TSA) is represented by a scalar function, called Topological Derivative (TD), that gives for each point of the domain the sensitivity of a given cost function when an infinitesimal hole is created. Applications to the Laplace, Poisson, Helmoltz, Navier, Stokes and Navier-Stokes equations can be found in the literature. I
Latin American Journal of Solids and Structures. Publicado em: 2010
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4. Análise de sensibilidade topológica em modelos constitutivos multi-escalas / Topological Sensitivity Analysis in Constitutive Multi-Scale Models
The purpose of the present work is to carry out a topological sensitivity analysis in constitutive multi-scale models. By making use of the Hill-Mandel Principle of Macro-Homogeneity and the concept of volume average, a variational formulation was established to derive a clearly structured axiomatic framework for constitutive multi-scale models of the presen
Publicado em: 2009
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5. Análise de sensibilidade topológica de segunda ordem / Second order topological sensitivity analysis
The topological derivative provides the sensitivity of a given shape functional with respect to an infinitesimal non-smooth domain pertubation (insertion of hole or inclusion, for instance). Classically, this derivative comes from the second term of the topological asymptotic expansion, dealing only with inifinitesimal pertubations. However, for pratical app
Publicado em: 2008
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6. Topological sensivity analysis in problems with geometric non-linearities and nonlinear nearly-incompressible hiperelasticity / Analise de sensibildade topologica em problemas de não-linearidade geometrica e hiperelasticidade não-linear quasi-incompressivel
The aim of the present work is to optimize the topology of elasticity problems with geometric nonlinearities (large displacement and rotation) and material nonlinearities, in this case, nonlinear nearly-incompressible hyperelasticity applying the concept of Topological Sensitivity Analysis (TSA) and a total Lagrangian formulation. The TSA results in a scalar
Publicado em: 2006
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7. Análise de Sensibilidade Topológica / Topological Sensitivity Analysis
The Topological Sensitivity Analysis results in a scalar function, denoted as Topological Derivative, that supplies for each point of the domain of definition of the problem the sensitivity of a given cost function when a small hole is created. However, when a hole is introduced, it is no longer possible to stablish a homeomorphism between the domains. Due t
Publicado em: 2003
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8. Aplicação do conceito de derivada topologica na otimização estrutural de problemas da elasticidade
This work deals with the application of the topological derivative to obtain the optimal topology of elastic problems. The topological derivative defines the sensitivity of a cost function, defined over the domain, to the creation of a hole. In this work, the topological derivative is obtained based on shape design sensitivity analysis concepts. In this way,
Publicado em: 2002
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9. Coumarin and quinolone action in archaebacteria: evidence for the presence of a DNA gyrase-like enzyme.
The action of novobiocin and coumermycin (two coumarins which interact with the gyrB subunit of eubacterial DNA gyrase) and ciprofloxacin (a fluoroquinolone which interacts with the gyrA subunit of DNA gyrase) was tested on several archaebacteria, including five methanogens, two halobacteria, and a thermoacidophile. Most strains were sensitive to doses of co
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10. Biparental products of bacterial protoplast fusion showing unequal parental chromosome expression.
Efficiently regenerated single colonies from mixed multiply auxotrophic Bacillus subtilis protoplasts, fused with polyethylene glycol, reveal colonies carrying each of the parent types (biparentals) and recombinant colonies. The latter appear in high yields (up to 1% of certain recombinant classes); the yield of biparentals may be as large as 10%, in the ran
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11. Genetic and topological analyses of the bop promoter of Halobacterium halobium: stimulation by DNA supercoiling and non-B-DNA structure.
The bop gene of wild-type Halobacterium halobium NRC-1 is transcriptionally induced more than 20-fold under microaerobic conditions. bop transcription is inhibited by novobiocin, a DNA gyrase inhibitor, at concentrations subinhibitory for growth. The exposure of NRC-1 cultures to novobiocin concentrations inhibiting bop transcription was found to partially r