Tissue Mechanics
Mostrando 1-12 de 40 artigos, teses e dissertações.
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1. Mecânica respiratória de pacientes com obesidade mórbida
RESUMO Objetivo avaliar os diferentes componentes da resistência do sistema respiratório e a força muscular respiratória, bem como investigar a ocorrência de limitação de fluxo expiratório (LFE) de pacientes obesos mórbidos (OM) na posição sentada. Métodos a amostra foi composta de OM (IMC ≥ 40 kg/m2) e de indivíduos não obesos (NO) com IMC
J. bras. pneumol.. Publicado em: 17/10/2019
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2. Microarchitecture and Radiological Flow Pattern of Cocoon-like Nanocellulose Hydrogels
Abstract This work investigates fluid mechanics and structural properties inside bacterial cellulose hydrogels in from of macroscopic anisotropic ellipsoid body cocoon-like 3D scaffolds. The hydrogels were evaluated by injections of iopamidol, a radiopaque medium used in medical radiological procedures. Results showed that hydromechanical behavior of BC hydr
Mat. Res.. Publicado em: 07/01/2019
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3. Chronic heart failure modifies respiratory mechanics in rats: a randomized controlled trial
ABSTRACT Objective To analyze respiratory mechanics and hemodynamic alterations in an experimental model of chronic heart failure (CHF) following myocardial infarction. Method Twenty-seven male adult Wistar rats were randomized to CHF group (n=12) or Sham group (n=15). Ten weeks after coronary ligation or sham surgery, the animals were anesthetized and sub
Braz. J. Phys. Ther.. Publicado em: 08/04/2016
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4. Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of
Clinics. Publicado em: 2015-08
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5. Assessment of the mechanics of a tissue-engineered rat trachea in an image-processing environment
OBJECTIVES:Despite the recent success regarding the transplantation of tissue-engineered airways, the mechanical properties of these grafts are not well understood. Mechanical assessment of a tissue-engineered airway graft before implantation may be used in the future as a predictor of function. The aim of this preliminary work was to develop a noninvasive i
Clinics. Publicado em: 2014-07
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6. Tratamento com inibidor da Rho quinase em cobais com inflamação pulmonar alérgica crônica: modulação da inflamação eosinofílica, da expressão de citocinas inflamatórias, da matriz extracelular e do estresse oxidativo no parênquima pulmonar / Treatment with Rho-kinase inhibitor in guinea pigs with chronic allergic inflammation: modulation of eosinophilic inflammation, expression of inflammatory cytokines, extracellular matrix and oxidative stress in lung tissue
RATIONALE: Previous studies with Rho-kinase inhibitors suggest a beneficial influence of these drugs in asthma. The relevance of distal lung tissue in functional asthmatic impairment has been intensely emphasized. There have not been any previous studies evaluating the effects of these inhibitors on the modulation of distal lung mechanics and histopathologic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/12/2012
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7. Short-term exposure of mice to cigarette smoke and/or residual oil fly ash produces proximal airspace enlargements and airway epithelium remodeling
Chronic obstructive pulmonary disease (COPD) is associated with inflammatory cell reactions, tissue destruction and lung remodeling. Many signaling pathways for these phenomena are still to be identified. We developed a mouse model of COPD to evaluate some pathophysiological mechanisms acting during the initial stage of the disease. Forty-seven 6- to 8-week-
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-05
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8. Inactivation of capsaicin-sensitive nerves reduces pulmonary remodeling in guinea pigs with chronic allergic pulmonary inflammation
Pulmonary remodeling is an important feature of asthma physiopathology that can contribute to irreversible changes in lung function. Although neurokinins influence lung inflammation, their exact role in the extracellular matrix (ECM) remodeling remains to be determined. Our objective was to investigate whether inactivation of capsaicin-sensitive nerves modul
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-02
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9. Respiratory mechanics do not always mirror pulmonary histological changes in emphysema
OBJECTIVE: To verify the accordance of functional and morphometric parameters during the development of emphysema. METHODS: BALB/c mice received a nasal drop of either papain or saline solution and were studied after 1, 3, 15, 28, and 40 days. Functional parameters, such as airway resistance, tissue damping, and tissue elastance, were analyzed. To evaluate t
Clinics. Publicado em: 2011
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10. Structural model with contact between pulmonary alveolus walls. / Modelo estrutural com contato entre paredes de alvéolo pulmonar.
This work is an important step on the development of a computational model of lung parenchyma capable to simulate mechanical ventilation maneuveres. The lung has a complex and hierarchized structure. Therefore a multidisciplinary literature review was held. The review presents the mechanical properties of the parenchyma, its morphology and the effects of sur
Publicado em: 2010
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11. Estrutura e funcionamento dos espermatóforos de Doryteuthis plei (Mollusca: Cephalopoda) e reavaliação da reação espermatofórica dos cefalópodes / Spermatophore structure and functioning in Doryteuthis plei (Mollusca: Cephalopoda), and a reappraisal of the cephalopod spermatophoric reaction
Male coleoid cephalopods produce elaborate spermatophores, which are transferred to the female during mating. These spermatophores are capable of functioning autonomously and extracorporeally, undergoing complicated changes during the so-called spermatophoric reaction, i.e., a complex process of evagination of the spermatophoric tunics and membranes that, ul
Publicado em: 2010
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12. O estresse físico modula a mecânica de tecido pulmonar periférico, a expressão de citocinas e o estresse oxidativo em cobaias com inflamação alérgica crônica / Physical stress modulates lung tissue mechanics, cytokines and oxidative stress activation in guinea pigs with chronic allergic inflammation
There are evidences showing that stress can worsen asthma symptoms, but the exact mechanisms that link them are not clarified, especially in the distal lung parenchyma. Recently, the importance of the lung parenchyma has been emphasized in the modulations of the functional alterations, inflammatory and remodeling that characterizes asthma. These alterations
Publicado em: 2009