Tiromimeticos
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Síntese e avaliação farmacológica de derivados fenóxi-acetoacetatos em receptores ativadados por proliferadores peroxissomais e em receptores de hormônio tireoideano
Nuclear receptors (NRs) are of great importance for the worldwide drug market since they are involved in mechanisms which influence several diseases that affect humanity like, for instance, diabetes mellitus (DM2), obesity, dislypemia and atherosclerosis. Peroxisome Proliferator-Activated Receptors (PPAR) and Thyroid Hormone Receptors (TR) control important
Publicado em: 2008
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2. Structural studies of the thyroid receptor (TR) and homology modeling of the thyroxine binding globulin (TBG) / Estudos estruturais do receptor do hormônio tireoidiano (hTR) e modelagem por homologia da globulina de ligação à tiroxina (TBG)
The thyroid hormones are involved in various regulatory effects, on diverse organs. Their fluctuations on the body are related to clinical scenarios of great relevance. This work deals with the study of two proteins which are directly related to the regulatory system associated to these hormones. The first one is the thyroxine-binding globulin (TBG), respons
Publicado em: 2005