Thioredoxin
Mostrando 13-24 de 415 artigos, teses e dissertações.
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13. Analysis of the stress-inducible transcription factor SsNAC23 in sugarcane plants
Stresses such as cold and drought can impair plant yield and induce a highly complex array of responses. Sugarcane (Saccharum spp.) is cultivated in tropical and subtropical areas and is considered a cold-sensitive plant. We previously showed that cold stress induces the expression of several genes in in vitro sugarcane plantlets. Here we characterize one of
Scientia Agricola. Publicado em: 2011-08
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14. Efeito da creatina e do piruvato sobre alguns parâmetros comportamentais e bioquímicos em ratos submetidos à administração intra-hipocampal de fenilalanina
The objective of this work was to investigate the possible preventive effect of pyruvate and creatine (substances with energetic and antioxidant properties) on the behavioral and biochemical alterations caused by intrahippocampal administration of phenylalanine (Phe) in Wistar rats. It was developed a experimental chemical model of phenylketonuria(PKU) by in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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15. Identificação de interatores putativos envolvidos na localização de proteínas de duplo direcionamento em Arabidopsis thaliana / Identification of putative interactors involved in the localization of dual-targeted proteins in Arabidopsis thaliana
Most organellar proteins are nuclear encoded, synthesized in the cytosol and then targeted to their destination. Specific subcellular targeting is conducted by a complex machinery for the specific localization of the proteins, which includes targeting sequences, cytosolic proteins and specific organelar receptors. However, little is known about the process t
Publicado em: 2011
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16. Adaptação oxidativa e funcional progressiva do sistema cardiopulmonar secundária à hipertensão arterial pulmonar em ratos
Pulmonary Arterial Hypertension (PAH) is a disease that affects the pulmonary vessels, essentially pre-capillaries, leading to remodeling of the vascular wall. It is characterized hemodynamic syndrome, which is the increase in pulmonary vascular resistance and right ventricular afterload. A growing body of evidence shows the involvement of oxidative stress i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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17. Clonagem e expressão do gene da tiorredoxina 1 de Paracoccidioides brasiliensis em Pichia pastoris / Cloning and expression of the thioredoxin 1 gene of Paracoccidioides brasiliensis in pichia pastoris
The termodimorphic fungus Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, a human systemic mycosis of high prevalence in Latin America. P. brasiliensis is exposed to oxidative stress (OS) caused by reactive oxygen species (ROS) produced by the defense cells of the human host. When the invasion by pathogens occurs, the host d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/08/2010
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18. Mechanisms of methilmercury toxicity: protective effect of flavonoids / ESTUDO DE MECANISMOS DE TOXICIDADE DO METILMERCÚRIO: PAPEL PROTETOR DE FLAVONÓIDES
O metilmercúrio (MeHg) é um importante agente tóxico ambiental que pode causar desordens neurocomportamentais e neurofisiológicas irreversíveis em humanos e animais experimentais. Os principais mecanismos pelos quais o MeHg induz toxicidade são: a ruptura na homeostase do cálcio intracelular, a indução de estresse oxidativo, a inibição da atividad
Publicado em: 2010
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19. Structural studies of the proteins Q4DV70 from Trypanosoma cruzi and mesothelin from Homo sapiens / Estudos estruturais das proteinas Q4DV70 de Trypanosoma cruzi e mesotelina de Homo sapiens
In this work we carried out studies with two proteins, Q4DV70 from Trypanosoma cruzi and mesothelin from Homo sapiens. The aim was to help the understanding of the function of these proteins which possibly are important to Chagas disease and cancer, respectively. Q4DV70 protein was annotated in T. cruzi genome as a conserved hypothetical protein. In our stud
Publicado em: 2009
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20. Interações de peroxirredoxinas citossólicas da levedura Saccharomyces cerevisiae com peróxidos. Estudos cinéticos e funcionais / Saccharomyces cerevisiae cytosolic peroxiredoxin interactions with peroxides. Kinetics and functional studies
Peroxiredoxins constitute a family of cysteine-based peroxidases that are able to reduce hydrogen peroxide, organic peroxides and peroxinitrite to water, alcohol and nitrite, respectively, through the use of reducing equivalents provided by thioredoxin, thioredoxin reductase and NADPH. Peroxiredoxins are abundant enzymes (correspond to approximately 0.7% of
Publicado em: 2009
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21. Inhibitory effect of ebselen, diphenyl disselenide, diphenyl diteluride on LDH activity from mammals / Efeito inibitório do Ebselen, do Disseleneto de Difenila e do Ditelureto de Difenila sobre a atividade da LDH de mamíferos
Ebselen is a seleno compound whose antioxidant properties have been attributed to its thiol-peroxidase and thioredoxin-like activity: it decomposes peroxides at the expense of reduced thiols. However, the excessive oxidation of thiols can be potentially toxic when it is not associated with peroxides degradation. Thus, this work investigated if LDH can be a p
Publicado em: 2009
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22. Efeitos do chumbo sobre a atividade da tioredoxina redutase citosólica (TrxR1) e parâmetros de estresse oxidativo em rins de ratos. / Effects of lead acetate exposure on renal cytosolic thioredoxin reductase (TrxR1) activity and on indicators of lead exposure.
Lead is a heavy metal that accumulates primarily in kidney, where exerts its nephrotoxic effects. Several studies suggest that the oxidative stress is an important molecular mechanism for the toxic effects of lead in kidney and in other organs. Cytosolic thioredoxin reductase (TrxR1) is a selenoflavoprotein involved in many processes modulating intracellular
Publicado em: 2007
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23. Caracterização Molecular e Expressão Heteróloga de um cDNA Codificante para Tiorredoxina do fungo patogênico humano Paracoccidioides brasiliensis / Cloning expression and insulin reduction activity analysis of a thioredoxin homalogue of human pathologe Paracoccidioides brasiliensis
O fungo termodimórfico, Paracoccidioides brasiliensis, é o agente etiológico da paracoccidioidomicose (PCM), uma micose sistêmica humana, com alta prevalência na América Latina. No hospedeiro humano, o fungo P. brasiliensis está sujeito a vários insultos, tais como o estresse oxidativo causado pelas espécies reativas de oxigênio, que são produzida
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2006
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24. Caracterização Molecular e Expressão Heteróloga de um cDNA Codificante para Tiorredoxina do fungo patogênico humano Paracoccidioides brasiliensis / Cloning expression and insulin reduction activity analysis of a thioredoxin homalogue of human pathologe Paracoccidioides brasiliensis
The temperature-dependent dimorphic fungus Paracoccidioides brasiliensis is the etiological agent of Paracoccidioidomycosis (PCM), a human systemic mycosis highly prevalent in countries of Latin America. P. brasiliensis is subjected to different insults from human host, such as oxidative stress caused by reactive oxygen species produced by the host during th
Publicado em: 2006