Thiols
Mostrando 13-24 de 247 artigos, teses e dissertações.
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13. Synthesis and biological activity of sulfur compounds showing structural analogy with combretastatin A-4
We extended our previous exploration of sulfur bridges as bioisosteric replacements for atoms forming the bridge between the aromatic rings of combretastatin A-4. Employing coupling reactions between 5-iodo-1,2,3-trimethoxybenzene and substituted thiols, followed by oxidation to sulfones with m-CPBA, different locations for attaching the sulfur atom to ring
Quím. Nova. Publicado em: 2013
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14. ATIVIDADE DE ECTOENZIMAS E DE COLINESTERASES E BIOMARCADORES DE ESTRESSE OXIDATIVO EM PACIENTES COM CÂNCER DE PULMÃO / ACTIVITY OF ECTOENZIMAS AND CHOLINESTERASES AND OXIDATIVE STRESS BIOMARKERS IN PATIENTS WITH LUNG CANCER
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world population, which is clearly seen in statistics, is closely related to smoking, and smoking is considered one of the main risk factors that le
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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15. PREPARAÇÃO, CARACTERIZAÇÃO E ESTUDOS ELETROQUÍMICOS DE ELETRODOS MODIFICADOS COM DIFERENTES MONOCAMADAS AUTOORGANIZADAS
In this work were studied investigated different types of modifiers for the formation of self-assembled monolayers on the gold surface. The monolayers used were formed by different structural arrangements, alkyl chains and functional groups. The thiols groups used were: 3-mercaptopropionic acid (MPA), thiolactic acid (TLA), cystamine (CYS) and 11-mercaptound
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/03/2011
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16. Estresse oxidativo em trigo causado por diferentes disponibilidade de fósforo em solução hidropônica / Oxidative stress in wheat caused by different availabilities of phosphorus in hidroponics
Phosphorus (P) is one of the most important nutrients for plant growth. However, it is known that its availability is often hampered by the presence of chelating substances in the soil, which turns it unavailable. In order to study the oxidative stress caused by different concentrations of P in two cultivars of wheat, Toropi (tolerant) and Anahuac (sensitive
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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17. Addition of thiols to phenylselenoalkynes using KF/Alumina under solvent-free conditions
Um método simples e eficiente foi desenvolvido para a hidrotiolação de fenilselenoalquinos utilizando KF/Al2O3 em meio livre de solvente. O método é geral e permite a preparação seletiva de (Z)-1-fenilseleno-2-organotio-1-alquenos a partir de tióis aromáticos e alifáticos em rendimentos de razoáveis a bons. A presença do grupamento organosselêni
Journal of the Brazilian Chemical Society. Publicado em: 2010
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18. PhSeBr-catalyzed selective addition of thiols to α,β-unsaturated carbonyl compounds: regioselective synthesis of thioacetals vs. β-mercapto ketones
Apresentamos aqui nossos resultados da adição de tióis, catalisada por PhSeBr, a compostos carbonílicos α,β-insaturados sob condições brandas para obter regiosseletivamente β-mercapto cetonas ou tioacetais com altos rendimentos e seletividade. A reação foi principalmente controlada pela temperatura, na qual os produtos de adição 1,4 foram obtido
Journal of the Brazilian Chemical Society. Publicado em: 2010
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19. Ischemic preconditioning reduces peripheral oxidative damage associated with brain ischemia in rats
Brain ischemia followed by reperfusion causes neuronal death related to oxidative damage. Furthermore, it has been reported that subjects suffering from ischemic cerebrovascular disorders exhibit changes in circulating platelet aggregation, a characteristic that might be important for their clinical outcome. In the present investigation we studied tert-butyl
Publicado em: 2010
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20. EFEITOS BIOQUÍMICOS E FISIOLÓGICOS DO CHUMBO EM PLANTAS DE QUITOCO (Pluchea sagittalis): POSSÍVEL PAPEL FITORREMEDIADOR / EFFECTS OF LEAD ON BIOCHEMICAL AND PHYSIOLOGICAL PARAMETERS IN QUITOC PLANTS (Pluchea sagittalis): POSSIBLE PHYTOREMEDIATOR ROLE
Lead (Pb) is one of the most abundant, globally distributed toxic elements. Soil, water and air contamination by Pb leads to its accumulation in fish, mammals, and plants, and thus to human intoxication through food. Due to the hazardous effects to the ecosystem, it is necessary that contaminated soils be rehabilitated. Phytoremediation is a cheap technique
Publicado em: 2010
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21. BIOCHEMICAL AND PHYSIOLOGICAL RESPONSES OF Cucumis sativus AND Avena sativa TO EXCESS ALUMINUM STRESS. / RESPOSTAS BIOQUÍMICAS E FISIOLÓGICAS DE Cucumis sativus E Avena sativa AO ESTRESSE CAUSADO POR ALUMÍNIO
Aluminum (Al) is the most abundant metal in the Earth s crust, affecting growth and development of plants. The aim of this study was to investigate the effects of Al on seedlings of cucumber (Cucumis sativus L.) and oat (Avena sativa L) through the analysis of biochemical and physiological parameters. Three different genotypes of oat seedlings were studied,
Publicado em: 2010
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22. Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment
Human serum albumin (HSA) is the most abundant protein in the intravascular compartment. It possesses a single thiol, Cys34, which constitutes ~80% of the total thiols in plasma. This thiol is able to scavenge plasma oxidants. A central intermediate in this potential antioxidant activity of human serum albumin is sulfenic acid (HSA-SOH). Work from our labora
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-04
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23. SiO2·p-TSA: a green catalyst for solvent-free tetrahydropyranylation of alcohols and thiols
Foi desenvolvido um procedimento para tetrahidropiranilação de álcoois e tióis em ausência de solvente orgânico, baseado na simples mistura dos reagentes, na presença de sílica gel e quantidade catalítica de p-TSA.
Journal of the Brazilian Chemical Society. Publicado em: 2009
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24. Inhibitory effect of ebselen, diphenyl disselenide, diphenyl diteluride on LDH activity from mammals / Efeito inibitório do Ebselen, do Disseleneto de Difenila e do Ditelureto de Difenila sobre a atividade da LDH de mamíferos
Ebselen is a seleno compound whose antioxidant properties have been attributed to its thiol-peroxidase and thioredoxin-like activity: it decomposes peroxides at the expense of reduced thiols. However, the excessive oxidation of thiols can be potentially toxic when it is not associated with peroxides degradation. Thus, this work investigated if LDH can be a p
Publicado em: 2009