Thioacetamide
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Effect of lesimarin against thioacetamide-induced liver cirrhosis in rat
Liver cirrhosis is one of chronic liver diseases with high disability and mortality accompanying fibrosis, hepatocyte damage, and liver dysfunction. In this study, the hepatoprotective and the antifibrotic properties of lesimarin(lecithin - silymarin - Artemisia messerschmitiana Besser(AMB) extract complex at 11:3:6 ratio) on rat hepatic fibrosis induced by
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Hepatoprotective and antineoplastic potencial of red propolis produced by the bees Apis mellifera in the semiarid of Rio Grande do Norte, Brazil
RESUMO: Este estudo objetivou avaliar o efeito hepatoprotetor do extrato etanólico da própolis vermelha da abelha Apis mellifera, obtido em quatro municípios do semiárido do Rio Grande do Norte, mediante avaliação in vitro do potencial antineoplásico em linhagens de células de carcinoma hepático humano (HepG2) e em linhagens de células normais (L92
Pesq. Vet. Bras.. Publicado em: 04/11/2019
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3. The role of oxymatrine in regulating TGF-β1 in rats with hepatic fibrosis
Abstract Purpose: To investigate whether oxymatrine (OMT) prevents hepatic fibrosis in rats by regulating liver transforming growth factor β1 (TGF-β1) level. Methods: Hepatic fibrosis was induced in rats by thioacetamide (TAA). Blood was collected at the end of week 12 to determine the levels of alanine aminotransferase (ALT), aspartate aminotransferas
Acta Cir. Bras.. Publicado em: 2018-03
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4. Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats
Minimal hepatic encephalopathy is more common than the acute syndrome. Losartan, the first angiotensin-II receptor blocker (ARB), and candesartan, another widely-used ARB, have protected against developing fibrogenesis, but there is no clear data about their curative antifibrotic effects. The current study was designed to examine their effects in an already-
Braz J Med Biol Res. Publicado em: 21/09/2017
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5. Efeito da hepatectomia parcial associada à administração de fatores nutricionais hepatotróficos sobre a morfologia, função e expressão de genes pró-fibróticos na cirrose hepática em ratos Wistar induzida por tiocetamida / Effects of partial hepatectomy associated with administration of nutritional hepatotrophic factors in morphology, function and expression of pro-fibrotic genes in thioacetamide-induced liver cirrhosis in Wistar rats
The current study evaluated the role of parenteral solution of nutritional hepatotrophic factors in animals with cirrhosis undergoing partial hepatectomy. This procedure is fearful in these animals due to the possibility of acute liver failure, since removal of a liver fragment further reduces the functional capacity of an already compromised organ. Moreover
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/12/2011
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6. Evaluation of hepatoprotective activity of aqueous and ethanolic extract of Oxalis corniculata against intoxication of thioacetamide induced rats
The present study was carried out to evaluate the hepatoprotective activity of aqueous and ethanolic leaves extracts of Oxalis corniculata L., Oxalidaceae, against thioacetamide-induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats of either sex by subcutaneous injection of thioacetamide. An aqueous and ethanolic extract of aerial parts of O. cor
Revista Brasileira de Farmacognosia. Publicado em: 14/10/2011
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7. A quercetina protege o fígado na lesão hepática induzida por tiocetamida (TAA) e suas complicações
Drug-induced liver injury is an increasing health problem and a challenge for physicians, regulatory bodies and the pharmaceutical industry, not only because of its potential severity and elusive pathogenesis but also because it is often inaccurately diagnosed, commonly missed entirely and more often not reported. Drug metabolism studies, together with patho
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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8. CGS based solar cells with In2S3 buffer layer deposited by CBD and coevaporation
In this paper we investigated In2S3 as substitute for CdS, which is conventionally used as buffer layer in chalcopyrite based solar cells. In2S3 thin films were deposited by CBD and co-evaporation methods and these were employed as buffer layer in CuGaSe2 based solar cells. Previous to the device fabrication, comparative study was carried out on In2S3 thin f
Brazilian Journal of Physics. Publicado em: 2010-03
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9. Modulation of extracellular matrix by nutritional hepatotrophic factors in thioacetamide-induced liver cirrhosis in the rat
Nutritional substances associated to some hormones enhance liver regeneration when injected intraperitoneally, being denominated hepatotrophic factors (HF). Here we verified if a solution of HF (glucose, vitamins, salts, amino acids, glucagon, insulin, and triiodothyronine) can revert liver cirrhosis and how some extracellular matrices are affected. Cirrhosi
Brazilian Journal of Medical and Biological Research. Publicado em: 25/09/2009
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10. A influência dos pontos de acupuntura Zusanli (E36) e Sanyinjiao (BP6) no desenvolvimento de lesões hepáticas induzidas por Tioacetamida, em ratos Wistar / The influence of the acupuncture points Zusanli (ST36) and Sanyinjiao (SP6) in the development of hepatic lesions induced by thioacetamide in Wistar rats
O fato da acupuntura ser atualmente considerada eficaz no tratamento de muitos processos patológicos e do fígado ser um órgão alvo de muitas enfermidades tanto em animais como em seres humanos, motivou a realização deste estudo que tem por objetivo verificar o efeito da eletroacupuntura durante a progressão de lesões hepáticas e o seu relacionamento
Publicado em: 2009
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11. Hepatic cirrhosis induced by thioacetamide: study of the model of intraperitoneal long term administration in Wistar rats / Cirrose hepática induzida por tioacetamida: estudo do modelo por injeção intraperitonial a longo prazo em ratas Wistar
A baixa sensibilidade dos animais à droga e a função hepática pouco alterada são as principais dificuldades para o desenvolvimento da cirrose hepática experimental. A proposta deste trabalho foi aprimorar o modelo de cirrose por injeção intraperitoneal de tioacetamida (TAA) a fim de reduzir a adaptação dos animais ao fármaco. Foram utilizados 5 gr
Publicado em: 2008
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12. Effect of hepatotrophic factors on thioacetamide-induced cirrhosis in rats / Efeito do tratamento com fatores hepatotróficos em ratas (Wistar) induzidas experimentalmente à cirrose por Tioacetamida
Cirrhosis is characterized by fibrosis and regenerative nodules, which result in the disorganization of the hepatic architecture, being considered an irreversible situation. The administration of exogenous hepatotrophic factors (EHF) could stimulate hepatic regeneration in hepatocytes cells and reduce the cirrhosis induced in rats. The aim of this work was t
Publicado em: 2006