Use of Direct Aqueous Injection and Solid Phase Extraction Coupled with Hydrophilic Interaction Chromatography to Analyze Haloacetic Acids in Drinking Water Samples

In this study, two analytical methods were evaluated to determine haloacetic acids (HAAs) in drinking water samples. Direct aqueous injection (DAI) and solid phase extraction (SPE) were evaluated and determination was performed by liquid chromatography tandem mass spectrometry (LC-MS/MS) with a hydrophilic interaction chromatography (HILIC) analytical column. Limits of quantification (LOQ) were between 10 and 500 µg L-1 by DAI and, considering a 125-fold pre concentration step, between 0.08 and 2.0 µg L-1 by SPE. Five HAAs exhibited good linear correlation coefficients, accuracy (70-120%) an...

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