11/08/2015

Tissue apoptosis in mice infected with Leptospira interrogans serovar Icterohaemorrhagiae

AbstractBackground:

This investigation aimed to evaluate the occurrence of some apoptotic features induced by Leptospira interrogans serovar Icterohaemorrhagiae infection in young BALB/c mice during 2, 4, 7, 10, 14 and 21 days post-infection (dpi).

Methods:

The animals were euthanized and lung, liver and kidneys were harvested to histopathology analysis and immunohistochemistry to caspase-3 antigen detection was performed.

Results:

Chromatin condensation in kidney and liver tissu...

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