Selectivity in the extraction of 2- quinolone alkaloids with supercritical CO2

This work describes the conditions for selective extraction of the alkaloids in Andreadoxa flava (Kallunki). The experiments were performed in a pilot plant SFE 500, in the following conditions. Extractor pressures 206.8 x 10(5), 241.3 x 10(5), 275.8 x 10(5) and 310.3 x 10(5) Pascal and pressures of 137.9 x 10(5), 69.0 x 10(5) and 55.2 x 10(5) Pascal for separators 6, 7 and 8 respectively. The temperatures were 40 °C in the extractor and 20 ºC in the separators. The samples, extracted from A. flava leaves, were analysed by ¹H NMR and GC/FID as well as by comparison with standards. This proc...