Qualitative histologic evaluation of the tissue reaction to the polyurethane resin (ricinus communis - based biopolymer) implantation assessed by light and scanning electron microscopy

The tissue reaction of bone tissue accessed by light microscopy and scanning electron microscopy (SEM) images after polyurethane resin implantation is presented in this study. Twenty four male rabbits were used, divided into two groups of 12 animals each (experimental group and control group) in which full-thickness cranial defect was surgically created. At 30 and 90 days post operation 6 animals of each group were euthanized and bone samples were removed for analysis. The microscopic results indicated no inflammatory foreign body reaction, a perfect union between the polymer and surgical bone...