2016-06

PROCEDIMENTO AUTOMÁTICO PARA DETERMINAÇÃO ESPECTROFOTOMÉTRICA DE HIDROQUINONA EMPREGANDO MULTICOMUTAÇÃO EM SISTEMA DE ANÁLISE EM FLUXO

This paper describes a procedure based on multicommutation in flow analysis system for photometric determination of hydroquinone in pharmaceutical gel formulations. The procedure involves oxidation of hydroquinone by Fe (III) and subsequent reaction between the generated Fe (II) species with 1,10-phenanthroline, producing a complex detected at 510 nm. Under optimized conditions, the proposed system showed a linear response in the range between 5 to 120 µmol L-1 (r = 0.9995), a limit of detection (3σ) 0.52 µmol L-1 and a relative standard deviation (RSD) of 1.5% for a 80 µmol L-1 hydroquino...

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