2014-12

Metabolic capabilities of Actinobacillus succinogenes for succinic acid production

Attention has been focused on microbial succinic acid production as an alternative for conventional chemical synthesis that is associated with environmental pollution. A metabolic model for Actinobacillus succinogenes 130Z was developed with a mixture of glucose and xylose as substrate. The metabolic fluxes during succinicate production were determined using flux balance analysis by linear programming optimization in the MATLAB environment. Different glucose ratios (0.3, 0.4 and 0.7 mol.mol-1substrate) were used as model assumptions to calculate optimal fluxes, maximum growth and succinate pro...

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