21/10/2019

HDL-PARTICLES SEPARATION EMPLOYING DIFFERENT PRECIPITATING AGENTS: FUNCTIONAL PROPERTIES OF THE IMPACT OF CHEMICAL PRECIPITATION ON LIPOPROTEIN PARTICLE-SIZE AND PARAOXONASE-1-ACTIVITY

First-generation methods used to quantify HDL-cholesterol have been used for decades. Therefore, first-generation precipitatingreagents still in use, the chemical impact on HDL-particles functionality (structure/activity-relationship) is not well-documented. The study aim was to identify the most efficient precipitating-reagent for lipoprotein separation to be used in the HDL functionalevaluation. A cross-sectional design with convenience sampling was conducted. Plasma samples from 40 individuals, both genders, were evaluated. Biochemical analysis was performed after using different chemical p...

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